Chit1 (chitinase 1) - Rat Genome Database

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Gene: Chit1 (chitinase 1) Rattus norvegicus
Analyze
Symbol: Chit1
Name: chitinase 1
RGD ID: 1305646
Description: Predicted to enable chitin binding activity and endochitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Orthologous to human CHIT1 (chitinase 1); PARTICIPATES IN amino sugar metabolic pathway; french type sialuria pathway; sialic acid storage disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chitinase 1 (chitotriosidase); chitotriosidase variant 1; chitotriosidase variant 2; chitotriosidase variant 3; chitotriosidase variant 4; chitotriosidase variant 5; chitotriosidase-1; LOC289032
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Candidate Gene For: Bp395
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,117,886 - 48,165,645 (+)NCBIGRCr8
mRatBN7.21345,565,841 - 45,613,593 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,593,845 - 45,613,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,174,113 - 48,221,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01349,462,167 - 49,509,762 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01346,726,964 - 46,774,804 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01350,947,020 - 50,994,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,974,872 - 50,994,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,000,134 - 56,046,972 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,095,240 - 47,109,367 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,059,518 - 47,123,204 (+)NCBI
Celera1345,894,357 - 45,941,716 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Congenic mapping and sequence analysis of the Renin locus. Flister MJ, etal., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11085997   PMID:17852345   PMID:19725875   PMID:23558346   PMID:24155872   PMID:35094663  


Genomics

Comparative Map Data
Chit1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,117,886 - 48,165,645 (+)NCBIGRCr8
mRatBN7.21345,565,841 - 45,613,593 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,593,845 - 45,613,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,174,113 - 48,221,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01349,462,167 - 49,509,762 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01346,726,964 - 46,774,804 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01350,947,020 - 50,994,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,974,872 - 50,994,643 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,000,134 - 56,046,972 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,095,240 - 47,109,367 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,059,518 - 47,123,204 (+)NCBI
Celera1345,894,357 - 45,941,716 (+)NCBICelera
Cytogenetic Map13q13NCBI
CHIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,216,079 - 203,230,099 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1203,212,827 - 203,273,641 (-)EnsemblGRCh38hg38GRCh38
GRCh371203,185,207 - 203,198,801 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,452,418 - 201,465,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 341199,917,451 - 199,930,433NCBI
Celera1176,314,462 - 176,328,121 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1174,350,361 - 174,364,019 (-)NCBIHuRef
CHM1_11204,607,543 - 204,621,196 (-)NCBICHM1_1
T2T-CHM13v2.01202,478,845 - 202,492,868 (-)NCBIT2T-CHM13v2.0
Chit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,038,980 - 134,079,279 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,038,980 - 134,079,278 (+)EnsemblGRCm39 Ensembl
GRCm381134,111,242 - 134,151,541 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,111,242 - 134,151,540 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,007,819 - 136,048,013 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,927,653 - 135,967,847 (+)NCBIMGSCv36mm8
Celera1136,728,484 - 136,764,033 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.12NCBI
Chit1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,229,356 - 39,241,540 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,229,161 - 39,253,328 (-)NCBIChiLan1.0ChiLan1.0
CHIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,148,307 - 46,167,361 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,115,349 - 46,134,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01178,816,396 - 178,875,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11183,112,412 - 183,126,052 (-)NCBIpanpan1.1PanPan1.1panPan2
Chit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,138,798 - 72,151,126 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,376,768 - 1,385,616 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,373,727 - 1,385,694 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHIT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,927,720 - 113,941,433 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,927,715 - 113,941,445 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,386,204 - 125,431,735 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,120,089 - 26,133,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605526,896,486 - 26,909,524 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chit1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248077,612,293 - 7,625,535 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248077,612,263 - 7,625,782 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chit1
456 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:210
Count of miRNA genes:128
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000035658
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134343790447841255Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134372077062022792Rat
12879436Bp395Blood pressure QTL 395arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134463918245700190Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134522835847841255Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat

Markers in Region
AW531798  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,613,356 - 45,613,561 (+)MAPPERmRatBN7.2
Rnor_6.01350,994,408 - 50,994,612NCBIRnor6.0
Rnor_5.01356,046,736 - 56,046,940UniSTSRnor5.0
RGSC_v3.41347,109,132 - 47,109,336UniSTSRGSC3.4
Celera1345,941,481 - 45,941,685UniSTS
RH 3.4 Map13183.9UniSTS
Cytogenetic Map13q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5 6 11
Low 3 35 45 29 14 29 8 11 59 35 35 8
Below cutoff 8 8 8 8 15

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001079689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008769542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ286232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000035658   ⟹   ENSRNOP00000036477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1345,604,183 - 45,613,592 (+)Ensembl
Rnor_6.0 Ensembl1350,977,431 - 50,994,643 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080768   ⟹   ENSRNOP00000070204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1345,593,845 - 45,613,592 (+)Ensembl
Rnor_6.0 Ensembl1350,974,872 - 50,994,643 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099352   ⟹   ENSRNOP00000096437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1345,593,845 - 45,613,415 (+)Ensembl
RefSeq Acc Id: NM_001079689   ⟹   NP_001073157
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,145,889 - 48,165,634 (+)NCBI
mRatBN7.21345,593,845 - 45,613,592 (+)NCBI
Rnor_6.01350,974,872 - 50,994,643 (+)NCBI
Rnor_5.01356,000,134 - 56,046,972 (+)NCBI
RGSC_v3.41347,095,240 - 47,109,367 (+)RGD
Celera1345,922,360 - 45,941,716 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270846   ⟹   NP_001257775
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,145,889 - 48,165,634 (+)NCBI
mRatBN7.21345,593,845 - 45,613,592 (+)NCBI
Rnor_6.01350,974,872 - 50,994,643 (+)NCBI
Rnor_5.01356,000,134 - 56,046,972 (+)NCBI
Celera1345,922,360 - 45,941,716 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270847   ⟹   NP_001257776
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,145,889 - 48,165,634 (+)NCBI
mRatBN7.21345,593,845 - 45,613,592 (+)NCBI
Rnor_6.01350,974,872 - 50,994,643 (+)NCBI
Rnor_5.01356,000,134 - 56,046,972 (+)NCBI
Celera1345,922,360 - 45,941,716 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270848   ⟹   NP_001257777
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,117,886 - 48,165,634 (+)NCBI
mRatBN7.21345,565,841 - 45,613,592 (+)NCBI
Rnor_6.01350,947,020 - 50,994,643 (+)NCBI
Rnor_5.01356,000,134 - 56,046,972 (+)NCBI
Celera1345,894,357 - 45,941,716 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090436   ⟹   XP_038946364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,152,126 - 48,165,645 (+)NCBI
mRatBN7.21345,600,095 - 45,613,593 (+)NCBI
RefSeq Acc Id: XM_039090437   ⟹   XP_038946365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81348,152,114 - 48,165,457 (+)NCBI
mRatBN7.21345,600,086 - 45,613,415 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001073157   ⟸   NM_001079689
- Peptide Label: precursor
- UniProtKB: A0S5V8 (UniProtKB/TrEMBL),   A6ICA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257777   ⟸   NM_001270848
- Peptide Label: precursor
- UniProtKB: A0S5V8 (UniProtKB/TrEMBL),   A6ICA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257775   ⟸   NM_001270846
- Peptide Label: precursor
- UniProtKB: A0S5V8 (UniProtKB/TrEMBL),   A6ICA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257776   ⟸   NM_001270847
- Peptide Label: precursor
- UniProtKB: A0S5V8 (UniProtKB/TrEMBL),   A6ICA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070204   ⟸   ENSRNOT00000080768
RefSeq Acc Id: ENSRNOP00000036477   ⟸   ENSRNOT00000035658
RefSeq Acc Id: XP_038946365   ⟸   XM_039090437
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AV32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946364   ⟸   XM_039090436
- Peptide Label: isoform X1
- UniProtKB: F7ER89 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096437   ⟸   ENSRNOT00000099352
Protein Domains
Chitin-binding type-2   GH18

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0S5V8-F1-model_v2 AlphaFold A0S5V8 1-464 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305646 AgrOrtholog
BioCyc Gene G2FUF-18253 BioCyc
Ensembl Genes ENSRNOG00000028072 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035658.6 UniProtKB/TrEMBL
  ENSRNOT00000080768 ENTREZGENE
  ENSRNOT00000080768.2 UniProtKB/TrEMBL
  ENSRNOT00000099352.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.50.10 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
InterPro Chitin-bd_dom_sf UniProtKB/TrEMBL
  Chitin-bd_peritrophin-A UniProtKB/TrEMBL
  Chitinase_II UniProtKB/TrEMBL
  Chitinase_insertion UniProtKB/TrEMBL
  Glyco_hydro18cat UniProtKB/TrEMBL
  Glyco_hydro_18_chit_AS UniProtKB/TrEMBL
  Glyco_hydro_catalytic_core UniProtKB/TrEMBL
KEGG Report rno:289032 UniProtKB/TrEMBL
NCBI Gene 289032 ENTREZGENE
PANTHER CHITINASE UniProtKB/TrEMBL
  CHITOTRIOSIDASE-1 UniProtKB/TrEMBL
Pfam CBM_14 UniProtKB/TrEMBL
  Glyco_hydro_18 UniProtKB/TrEMBL
PhenoGen Chit1 PhenoGen
PROSITE CHIT_BIND_II UniProtKB/TrEMBL
  CHITINASE_18 UniProtKB/TrEMBL
  GH18_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028072 RatGTEx
SMART Glyco_18 UniProtKB/TrEMBL
Superfamily-SCOP Chitin_bind_PerA UniProtKB/TrEMBL
  Glyco_hydro_cat UniProtKB/TrEMBL
  SSF54556 UniProtKB/TrEMBL
UniProt A0A8I6AV32 ENTREZGENE, UniProtKB/TrEMBL
  A0S5V8 ENTREZGENE, UniProtKB/TrEMBL
  A6ICA4 ENTREZGENE, UniProtKB/TrEMBL
  F7ER89 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-09 Chit1  chitinase 1  Chit1  chitinase 1 (chitotriosidase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Chit1  chitinase 1 (chitotriosidase)   Chit1_predicted  chitinase 1 (chitotriosidase) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Chit1_predicted  chitinase 1 (chitotriosidase) (predicted)      Symbol and Name status set to approved 70820 APPROVED