Reep1 (receptor accessory protein 1) - Rat Genome Database

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Gene: Reep1 (receptor accessory protein 1) Rattus norvegicus
Analyze
Symbol: Reep1
Name: receptor accessory protein 1
RGD ID: 1305230
Description: Predicted to enable microtubule binding activity and olfactory receptor binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization; protein insertion into membrane; and regulation of intracellular transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Human ortholog(s) of this gene implicated in autosomal dominant distal hereditary motor neuronopathy 12; autosomal recessive distal hereditary motor neuronopathy 6; and hereditary spastic paraplegia 31. Orthologous to human REEP1 (receptor accessory protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362384; receptor expression-enhancing protein 1; RGD1305230; similar to hypothetical protein FLJ13110
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,303,974 - 105,420,611 (+)NCBIGRCr8
mRatBN7.24103,746,004 - 103,862,347 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,745,633 - 103,862,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,126,200 - 109,242,259 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,901,318 - 105,017,375 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,516,012 - 103,632,244 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,618,622 - 99,735,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,618,622 - 99,735,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04164,396,429 - 164,513,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,982,925 - 105,099,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14105,227,462 - 105,342,336 (+)NCBI
Celera492,903,130 - 93,018,649 (+)NCBICelera
Cytogenetic Map4q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
chrysene  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
hexane  (EXP)
isoprenaline  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylseleninic acid  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
pravastatin  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15550249   PMID:20200447   PMID:24098485   PMID:24668814  


Genomics

Comparative Map Data
Reep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,303,974 - 105,420,611 (+)NCBIGRCr8
mRatBN7.24103,746,004 - 103,862,347 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,745,633 - 103,862,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,126,200 - 109,242,259 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,901,318 - 105,017,375 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,516,012 - 103,632,244 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,618,622 - 99,735,329 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,618,622 - 99,735,319 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04164,396,429 - 164,513,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,982,925 - 105,099,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14105,227,462 - 105,342,336 (+)NCBI
Celera492,903,130 - 93,018,649 (+)NCBICelera
Cytogenetic Map4q32NCBI
REEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38286,213,993 - 86,338,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl286,213,993 - 86,338,083 (-)EnsemblGRCh38hg38GRCh38
GRCh37286,441,116 - 86,565,206 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,294,633 - 86,418,288 (-)NCBINCBI36Build 36hg18NCBI36
Build 34286,352,779 - 86,476,435NCBI
Celera286,269,251 - 86,393,245 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef286,338,580 - 86,462,643 (-)NCBIHuRef
CHM1_1286,370,561 - 86,495,314 (-)NCBICHM1_1
T2T-CHM13v2.0286,216,087 - 86,340,099 (-)NCBIT2T-CHM13v2.0
Reep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,684,413 - 71,787,694 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,684,545 - 71,787,694 (+)EnsemblGRCm39 Ensembl
GRCm38671,707,429 - 71,810,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,707,561 - 71,810,710 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,657,854 - 71,760,696 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,637,369 - 71,740,211 (+)NCBIMGSCv36mm8
Celera673,791,587 - 73,894,394 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.2NCBI
Reep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554241,369,490 - 1,425,605 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554241,369,490 - 1,425,611 (+)NCBIChiLan1.0ChiLan1.0
REEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21240,044,484 - 40,168,054 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A40,047,245 - 40,170,815 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A86,268,147 - 86,391,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A87,814,041 - 87,881,687 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A87,814,047 - 87,936,984 (-)Ensemblpanpan1.1panPan2
REEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,807,217 - 38,908,434 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1738,807,014 - 38,906,196 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,493,572 - 38,594,217 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,540,817 - 39,641,510 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,540,187 - 39,642,151 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,706,876 - 38,807,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,743,145 - 38,843,963 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01739,129,124 - 39,230,115 (+)NCBIUU_Cfam_GSD_1.0
Reep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,614,597 - 79,696,048 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,206,276 - 1,241,301 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,186,565 - 1,241,829 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
REEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl358,436,324 - 58,558,934 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1358,436,319 - 58,558,943 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2361,264,880 - 61,327,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
REEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11420,819,318 - 20,924,484 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1420,820,275 - 20,940,683 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,546,477 - 91,668,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Reep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474916,933,576 - 17,043,753 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474916,933,575 - 17,042,017 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Reep1
447 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:356
Count of miRNA genes:223
Interacting mature miRNAs:274
Transcripts:ENSRNOT00000064772
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
8662350Eae35Experimental allergic encephalomyelitis QTL 356.2blood tumor necrosis factor amount (VT:0008552)inflammatory exudate tumor necrosis factor level (CMO:0001435)4100834579103761084Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4103194805112478794Rat

Markers in Region
D4Rat232  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24103,760,884 - 103,761,084 (+)MAPPERmRatBN7.2
Rnor_6.0499,633,759 - 99,633,958NCBIRnor6.0
Rnor_5.04164,411,665 - 164,411,864UniSTSRnor5.0
RGSC_v3.44104,998,051 - 104,998,251RGDRGSC3.4
RGSC_v3.44104,998,052 - 104,998,251UniSTSRGSC3.4
RGSC_v3.14105,242,532 - 105,242,732RGD
Celera492,917,864 - 92,918,063UniSTS
SHRSP x BN Map448.75UniSTS
SHRSP x BN Map448.75RGD
Cytogenetic Map4q33UniSTS
AI175348  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24103,862,098 - 103,862,266 (+)MAPPERmRatBN7.2
Rnor_6.0499,735,081 - 99,735,248NCBIRnor6.0
Rnor_5.04164,513,222 - 164,513,389UniSTSRnor5.0
RGSC_v3.44105,099,614 - 105,099,781UniSTSRGSC3.4
Celera493,018,411 - 93,018,578UniSTS
RH 3.4 Map4628.44UniSTS
Cytogenetic Map4q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 31 8 11 74 2 32 7 8
Low 3 12 56 40 19 40 28 9 4
Below cutoff 1 1 1 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064772   ⟹   ENSRNOP00000061062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4103,746,142 - 103,862,338 (+)Ensembl
Rnor_6.0 Ensembl499,618,622 - 99,735,319 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095632   ⟹   ENSRNOP00000087200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4103,746,100 - 103,862,337 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095813   ⟹   ENSRNOP00000085476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4103,776,615 - 103,862,337 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106214   ⟹   ENSRNOP00000082389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4103,746,142 - 103,862,338 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111989   ⟹   ENSRNOP00000090724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4103,745,633 - 103,862,337 (+)Ensembl
RefSeq Acc Id: NM_001108633   ⟹   NP_001102103
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,382 - 105,420,601 (+)NCBI
mRatBN7.24103,746,100 - 103,862,337 (+)NCBI
Rnor_6.0499,618,622 - 99,735,319 (+)NCBI
Rnor_5.04164,396,429 - 164,513,470 (+)NCBI
RGSC_v3.44104,982,925 - 105,099,852 (+)RGD
Celera492,903,130 - 93,018,649 (+)RGD
Sequence:
RefSeq Acc Id: XM_008762992   ⟹   XP_008761214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,317 - 105,420,611 (+)NCBI
mRatBN7.24103,746,035 - 103,862,347 (+)NCBI
Rnor_6.0499,618,637 - 99,735,329 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107807   ⟹   XP_038963735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,289 - 105,420,611 (+)NCBI
mRatBN7.24103,746,006 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_039107809   ⟹   XP_038963737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,309 - 105,420,611 (+)NCBI
mRatBN7.24103,746,027 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_039107810   ⟹   XP_038963738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,290 - 105,420,611 (+)NCBI
mRatBN7.24103,746,006 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_039107812   ⟹   XP_038963740
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,306 - 105,420,611 (+)NCBI
mRatBN7.24103,746,023 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_039107813   ⟹   XP_038963741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,332 - 105,420,611 (+)NCBI
mRatBN7.24103,746,048 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_039107814   ⟹   XP_038963742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,288 - 105,420,611 (+)NCBI
mRatBN7.24103,746,005 - 103,862,347 (+)NCBI
RefSeq Acc Id: XM_063286282   ⟹   XP_063142352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,303,974 - 105,420,611 (+)NCBI
RefSeq Acc Id: XR_005503256
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84105,304,289 - 105,415,291 (+)NCBI
mRatBN7.24103,746,006 - 103,857,012 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102103   ⟸   NM_001108633
- UniProtKB: A6IA87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761214   ⟸   XM_008762992
- Peptide Label: isoform X3
- UniProtKB: D4A193 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061062   ⟸   ENSRNOT00000064772
RefSeq Acc Id: XP_038963742   ⟸   XM_039107814
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZTG4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963735   ⟸   XM_039107807
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963738   ⟸   XM_039107810
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963740   ⟸   XM_039107812
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963737   ⟸   XM_039107809
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038963741   ⟸   XM_039107813
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GDV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090724   ⟸   ENSRNOT00000111989
RefSeq Acc Id: ENSRNOP00000087200   ⟸   ENSRNOT00000095632
RefSeq Acc Id: ENSRNOP00000082389   ⟸   ENSRNOT00000106214
RefSeq Acc Id: ENSRNOP00000085476   ⟸   ENSRNOT00000095813
RefSeq Acc Id: XP_063142352   ⟸   XM_063286282
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AD43 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A193-F1-model_v2 AlphaFold D4A193 1-201 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693116
Promoter ID:EPDNEW_R3641
Type:single initiation site
Name:Reep1_1
Description:receptor accessory protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0499,618,664 - 99,618,724EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305230 AgrOrtholog
BioCyc Gene G2FUF-44178 BioCyc
Ensembl Genes ENSRNOG00000008481 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064772 ENTREZGENE
  ENSRNOT00000064772.2 UniProtKB/TrEMBL
  ENSRNOT00000095632.1 UniProtKB/TrEMBL
  ENSRNOT00000095813.1 UniProtKB/TrEMBL
  ENSRNOT00000106214.1 UniProtKB/TrEMBL
  ENSRNOT00000111989 ENTREZGENE
  ENSRNOT00000111989.1 UniProtKB/TrEMBL
InterPro TB2_DP1_HVA22 UniProtKB/TrEMBL
KEGG Report rno:362384 UniProtKB/TrEMBL
NCBI Gene 362384 ENTREZGENE
PANTHER RECEPTOR EXPRESSION-ENHANCING PROTEIN 1 UniProtKB/TrEMBL
  TB2_DP1_HVA22 UniProtKB/TrEMBL
Pfam TB2_DP1_HVA22 UniProtKB/TrEMBL
PhenoGen Reep1 PhenoGen
RatGTEx ENSRNOG00000008481 RatGTEx
UniProt A0A8I5ZTG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AD43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AG42_RAT UniProtKB/TrEMBL
  A0A8I6GDV4 ENTREZGENE, UniProtKB/TrEMBL
  A6IA87 ENTREZGENE, UniProtKB/TrEMBL
  D4A193 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Reep1  receptor accessory protein 1   Reep1_predicted  receptor accessory protein 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Reep1_predicted  receptor accessory protein 1 (predicted)  RGD1305230_predicted  similar to hypothetical protein FLJ13110 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305230_predicted  similar to hypothetical protein FLJ13110 (predicted)  LOC362384_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362384_predicted  similar to hypothetical protein FLJ13110 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL