Il27ra (interleukin 27 receptor subunit alpha) - Rat Genome Database

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Gene: Il27ra (interleukin 27 receptor subunit alpha) Rattus norvegicus
Analyze
Symbol: Il27ra
Name: interleukin 27 receptor subunit alpha
RGD ID: 1305029
Description: Predicted to enable cytokine binding activity and interleukin-27 receptor activity. Predicted to be involved in several processes, including negative regulation of T cell extravasation; negative regulation of T-helper 17 type immune response; and negative regulation of cytokine production. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of type II interferon production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; LOC288905
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,014,730 - 41,026,740 (+)NCBIGRCr8
mRatBN7.21924,109,963 - 24,121,977 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,109,972 - 24,121,938 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1930,931,218 - 30,943,116 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,585,624 - 31,597,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,808,352 - 33,820,238 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,151,835 - 25,163,995 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,149,897 - 25,164,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,128,834 - 36,140,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,795,355 - 25,807,317 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11925,802,500 - 25,806,104 (+)NCBI
Celera1923,657,895 - 23,669,746 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. Holscher C, etal., J Immunol. 2005 Mar 15;174(6):3534-44.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice. Miyazaki Y, etal., J Immunol. 2005 Aug 15;175(4):2401-7.
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Amelioration of experimental allergic rhinitis with suppression of topical immune responses by lack of IL-27/WSX-1 signaling. Shimanoe Y, etal., Ann Allergy Asthma Immunol. 2009 Mar;102(3):223-32.
10. Elevated serum interleukin-27 levels in patients with systemic sclerosis: association with T cell, B cell and fibroblast activation. Yoshizaki A, etal., Ann Rheum Dis. 2011 Jan;70(1):194-200. Epub 2010 Aug 12.
Additional References at PubMed
PMID:11057672   PMID:12121660   PMID:22927332  


Genomics

Comparative Map Data
Il27ra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81941,014,730 - 41,026,740 (+)NCBIGRCr8
mRatBN7.21924,109,963 - 24,121,977 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1924,109,972 - 24,121,938 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1930,931,218 - 30,943,116 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01931,585,624 - 31,597,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01933,808,352 - 33,820,238 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01925,151,835 - 25,163,995 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1925,149,897 - 25,164,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01936,128,834 - 36,140,875 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,795,355 - 25,807,317 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11925,802,500 - 25,806,104 (+)NCBI
Celera1923,657,895 - 23,669,746 (+)NCBICelera
Cytogenetic Map19q11NCBI
IL27RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,031,762 - 14,053,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,031,762 - 14,053,218 (+)EnsemblGRCh38hg38GRCh38
GRCh371914,142,574 - 14,164,030 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,003,262 - 14,025,026 (+)NCBINCBI36Build 36hg18NCBI36
Build 341914,003,261 - 14,025,026NCBI
Celera1914,036,058 - 14,057,825 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1913,714,538 - 13,735,786 (+)NCBIHuRef
CHM1_11914,143,096 - 14,164,322 (+)NCBICHM1_1
T2T-CHM13v2.01914,158,051 - 14,179,508 (+)NCBIT2T-CHM13v2.0
Il27ra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,756,915 - 84,769,250 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl884,756,923 - 84,769,218 (-)EnsemblGRCm39 Ensembl
GRCm38884,030,286 - 84,042,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl884,030,294 - 84,042,589 (-)EnsemblGRCm38mm10GRCm38
MGSCv37886,554,185 - 86,566,474 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36886,920,423 - 86,932,680 (-)NCBIMGSCv36mm8
Celera888,323,361 - 88,337,096 (-)NCBICelera
Cytogenetic Map8C2NCBI
cM Map840.26NCBI
Il27ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,749,094 - 32,761,882 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541532,749,682 - 32,762,532 (+)NCBIChiLan1.0ChiLan1.0
IL27RA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22018,960,949 - 18,982,615 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11917,961,963 - 17,983,593 (+)NCBINHGRI_mPanPan1
PanPan1.11914,323,618 - 14,343,636 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,323,618 - 14,343,627 (+)Ensemblpanpan1.1panPan2
IL27RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,456,766 - 48,475,414 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,457,134 - 48,472,450 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2048,330,953 - 48,346,665 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02048,974,444 - 48,990,172 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2048,974,445 - 48,990,429 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12048,185,368 - 48,201,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02048,612,194 - 48,627,913 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02048,854,767 - 48,870,725 (-)NCBIUU_Cfam_GSD_1.0
Il27ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,634,220 - 207,649,537 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366592,705,985 - 2,722,748 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366592,706,037 - 2,720,486 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL27RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,127,287 - 65,149,740 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1265,127,278 - 65,149,665 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,401,420 - 65,423,808 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL27RA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1612,679,270 - 12,699,254 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl612,686,838 - 12,701,867 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,950,555 - 6,971,183 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il27ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249011,274,840 - 1,287,861 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249011,274,753 - 1,288,783 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Il27ra
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:71
Interacting mature miRNAs:81
Transcripts:ENSRNOT00000007726
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat

Markers in Region
D19Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.41925,801,629 - 25,801,740RGDRGSC3.4
RGSC_v3.41925,801,630 - 25,801,740UniSTSRGSC3.4
RGSC_v3.41925,801,630 - 25,801,739UniSTSRGSC3.4
RGSC_v3.11925,806,455 - 25,806,566RGD
Celera1923,664,170 - 23,664,280UniSTS
Celera1923,664,170 - 23,664,279UniSTS
SHRSP x BN Map1916.9499RGD
FHH x ACI Map1921.16RGD
Cytogenetic Map19 RGD
D19Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01936,134,451 - 36,134,560UniSTSRnor5.0
RGSC_v3.41925,801,630 - 25,801,739UniSTSRGSC3.4
Celera1923,664,170 - 23,664,279UniSTS
SHRSP x BN Map1916.9499UniSTS
Cytogenetic Map19q11UniSTS
D19Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01936,134,450 - 36,134,560UniSTSRnor5.0
RGSC_v3.41925,801,630 - 25,801,740UniSTSRGSC3.4
Celera1923,664,170 - 23,664,280UniSTS
Cytogenetic Map19q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2
Low 2 31 14 6 17 6 6 22 27 11
Below cutoff 1 12 41 34 34 4 5 63 13 14 4

Sequence


RefSeq Acc Id: ENSRNOT00000007726   ⟹   ENSRNOP00000007726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1924,109,972 - 24,121,938 (+)Ensembl
Rnor_6.0 Ensembl1925,151,995 - 25,163,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085630   ⟹   ENSRNOP00000069777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1925,149,897 - 25,164,086 (-)Ensembl
RefSeq Acc Id: NM_001395124   ⟹   NP_001382053
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81941,014,730 - 41,026,740 (+)NCBI
mRatBN7.21924,109,963 - 24,121,977 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001382053 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92242 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000007726
  ENSRNOP00000007726.6
RefSeq Acc Id: ENSRNOP00000069777   ⟸   ENSRNOT00000085630
RefSeq Acc Id: ENSRNOP00000007726   ⟸   ENSRNOT00000007726
RefSeq Acc Id: NP_001382053   ⟸   NM_001395124
- Peptide Label: precursor
- UniProtKB: D4A6K5 (UniProtKB/TrEMBL),   A6IYB4 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JW79-F1-model_v2 AlphaFold A0A0G2JW79 1-631 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701011
Promoter ID:EPDNEW_R11534
Type:initiation region
Name:Il27ra_1
Description:interleukin 27 receptor subunit alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01925,163,929 - 25,163,989EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305029 AgrOrtholog
BioCyc Gene G2FUF-6050 BioCyc
Ensembl Genes ENSRNOG00000005747 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007726 ENTREZGENE
  ENSRNOT00000007726.6 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
KEGG Report rno:288905 UniProtKB/TrEMBL
NCBI Gene 288905 ENTREZGENE
PANTHER INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA UniProtKB/TrEMBL
  INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
PhenoGen Il27ra PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005747 RatGTEx
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
UniProt A6IYB4 ENTREZGENE, UniProtKB/TrEMBL
  D4A6K5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-16 Il27ra  interleukin 27 receptor subunit alpha  Il27ra  interleukin 27 receptor, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Il27ra  interleukin 27 receptor, alpha   Il27ra_predicted  interleukin 27 receptor, alpha (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Il27ra_predicted  interleukin 27 receptor, alpha (predicted)      Symbol and Name status set to approved 70820 APPROVED