Jam3 (junctional adhesion molecule 3) - Rat Genome Database

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Gene: Jam3 (junctional adhesion molecule 3) Rattus norvegicus
Analyze
Symbol: Jam3
Name: junctional adhesion molecule 3
RGD ID: 1303248
Description: Predicted to enable cell-cell adhesion mediator activity; identical protein binding activity; and integrin binding activity. Involved in axon regeneration. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; desmosome; and paranodal junction. Predicted to be part of filamentous actin and protein complex involved in cell adhesion. Predicted to be active in cell-cell contact zone. Predicted to colocalize with bicellular tight junction. Biomarker of sciatic neuropathy. Orthologous to human JAM3 (junctional adhesion molecule 3); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: JAM-3; JAM-C; junctional adhesion molecule C; MGC94974
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8833,767,606 - 33,828,451 (-)NCBIGRCr8
mRatBN7.2825,508,461 - 25,569,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx829,550,421 - 29,611,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0827,844,708 - 27,905,552 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0825,724,719 - 25,785,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,147,110 - 28,208,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0828,166,275 - 28,227,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4826,697,127 - 26,758,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1826,697,127 - 26,758,579 (-)NCBI
Celera826,995,820 - 27,056,659 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetohydrazide  (ISO)
aconitine  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
anthracen-2-amine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diethyl maleate  (EXP)
endosulfan  (EXP)
epoxiconazole  (ISO)
fipronil  (EXP)
fonofos  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gemcitabine  (ISO)
Heliotrine  (EXP)
indometacin  (ISO)
Lasiocarpine  (EXP)
lead(0)  (ISO)
methapyrilene  (ISO)
methylmercury(1+)  (ISO)
N(4)-hydroxycytidine  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
senecionine  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The spatiotemporal localization of JAM-C following sciatic nerve crush in adult rats. Avari P, etal., Brain Behav. 2012 Jul;2(4):402-14. doi: 10.1002/brb3.63.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Targeting of junctional adhesion molecule-C inhibits experimental choroidal neovascularization. Hou X, etal., Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1584-91. doi: 10.1167/iovs.11-9005. Print 2012 Mar.
4. Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. Lamagna C, etal., Cancer Res. 2005 Jul 1;65(13):5703-10.
5. Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation. Ludwig RJ, etal., J Invest Dermatol. 2005 Nov;125(5):969-76.
6. Differential expression of junctional adhesion molecules in different stages of systemic sclerosis. Manetti M, etal., Arthritis Rheum. 2013 Jan;65(1):247-57. doi: 10.1002/art.37712.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. The proadhesive phenotype of systemic sclerosis skin promotes myeloid cell adhesion via ICAM-1 and VCAM-1. Rabquer BJ, etal., Rheumatology (Oxford). 2009 Jul;48(7):734-40. doi: 10.1093/rheumatology/kep091. Epub 2009 May 13.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11590146   PMID:11823489   PMID:12208882   PMID:15194813   PMID:15372036   PMID:15489334   PMID:15879142   PMID:16093349   PMID:17099249   PMID:17455169   PMID:17853450   PMID:18048693  
PMID:19060272   PMID:19109565   PMID:19342649   PMID:19461049   PMID:19740376   PMID:20592283   PMID:21097846   PMID:22871113   PMID:24357068   PMID:28196865  


Genomics

Comparative Map Data
Jam3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8833,767,606 - 33,828,451 (-)NCBIGRCr8
mRatBN7.2825,508,461 - 25,569,306 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx829,550,421 - 29,611,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0827,844,708 - 27,905,552 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0825,724,719 - 25,785,571 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0828,147,110 - 28,208,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0828,166,275 - 28,227,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4826,697,127 - 26,758,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1826,697,127 - 26,758,579 (-)NCBI
Celera826,995,820 - 27,056,659 (-)NCBICelera
Cytogenetic Map8q13NCBI
JAM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811134,069,072 - 134,152,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11134,069,071 - 134,152,001 (+)EnsemblGRCh38hg38GRCh38
GRCh3711133,938,967 - 134,021,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611133,444,030 - 133,526,861 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411133,444,029 - 133,526,858NCBI
Celera11131,112,218 - 131,194,832 (+)NCBICelera
Cytogenetic Map11q25NCBI
HuRef11129,893,248 - 129,976,188 (+)NCBIHuRef
CHM1_111133,826,755 - 133,908,474 (+)NCBICHM1_1
T2T-CHM13v2.011134,112,013 - 134,194,140 (+)NCBIT2T-CHM13v2.0
Jam3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39927,008,680 - 27,066,739 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl927,008,680 - 27,066,717 (-)EnsemblGRCm39 Ensembl
GRCm38927,097,384 - 27,155,421 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl927,097,384 - 27,155,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv37926,904,969 - 26,962,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36926,846,830 - 26,904,826 (-)NCBIMGSCv36mm8
Celera924,355,390 - 24,413,352 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map912.27NCBI
Jam3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541234,901,681 - 34,967,394 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541234,901,850 - 34,967,394 (+)NCBIChiLan1.0ChiLan1.0
JAM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29134,787,560 - 134,878,062 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111135,892,480 - 135,977,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011128,916,024 - 129,006,497 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111132,783,580 - 132,864,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11132,783,580 - 132,864,657 (+)Ensemblpanpan1.1panPan2
JAM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.151,082,619 - 1,165,188 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl51,084,560 - 1,165,121 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha51,202,269 - 1,285,185 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.051,038,590 - 1,121,616 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl51,038,594 - 1,121,627 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.151,071,730 - 1,155,064 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.051,072,117 - 1,155,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.051,109,856 - 1,192,622 (-)NCBIUU_Cfam_GSD_1.0
Jam3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947115,840,860 - 115,913,401 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366841,692,089 - 1,762,087 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366841,689,594 - 1,762,066 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JAM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl960,613,400 - 60,738,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1960,629,245 - 60,738,979 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2967,205,386 - 67,284,770 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JAM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11125,136,963 - 125,211,424 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666043831,362 - 904,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jam3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248128,643,921 - 8,707,351 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248128,644,002 - 8,707,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Jam3
124 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:612
Count of miRNA genes:244
Interacting mature miRNAs:301
Transcripts:ENSRNOT00000012247
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
1354595Despr4Despair related QTL 42.160.0036locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)8768895552688955Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)8873663553736635Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat

Markers in Region
RH143914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2825,508,834 - 25,508,991 (+)MAPPERmRatBN7.2
Rnor_6.0828,147,484 - 28,147,640NCBIRnor6.0
Rnor_5.0828,166,649 - 28,166,805UniSTSRnor5.0
RGSC_v3.4826,697,501 - 26,697,657UniSTSRGSC3.4
Celera826,996,194 - 26,996,350UniSTS
RH 3.4 Map8220.2UniSTS
Cytogenetic Map8q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 18 10 11 10 3 3 74 34 41 11 3
Low 3 39 31 8 31 5 8 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012247   ⟹   ENSRNOP00000012247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,508,473 - 25,569,303 (-)Ensembl
Rnor_6.0 Ensembl828,147,111 - 28,208,466 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100354   ⟹   ENSRNOP00000087591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,508,473 - 25,569,303 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100661   ⟹   ENSRNOP00000094560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,508,473 - 25,569,306 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101760   ⟹   ENSRNOP00000078492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,507,057 - 25,569,355 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110398   ⟹   ENSRNOP00000088272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl825,508,473 - 25,553,573 (-)Ensembl
RefSeq Acc Id: NM_001004269   ⟹   NP_001004269
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8833,767,606 - 33,828,451 (-)NCBI
mRatBN7.2825,508,461 - 25,569,306 (-)NCBI
Rnor_6.0828,147,110 - 28,208,466 (-)NCBI
Rnor_5.0828,166,275 - 28,227,631 (-)NCBI
RGSC_v3.4826,697,127 - 26,758,579 (-)RGD
Celera826,995,820 - 27,056,659 (-)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001004269   ⟸   NM_001004269
- Peptide Label: precursor
- UniProtKB: Q68FQ2 (UniProtKB/Swiss-Prot),   A6JYE0 (UniProtKB/TrEMBL),   A0A8I6ANI6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012247   ⟸   ENSRNOT00000012247
RefSeq Acc Id: ENSRNOP00000094560   ⟸   ENSRNOT00000100661
RefSeq Acc Id: ENSRNOP00000088272   ⟸   ENSRNOT00000110398
RefSeq Acc Id: ENSRNOP00000078492   ⟸   ENSRNOT00000101760
RefSeq Acc Id: ENSRNOP00000087591   ⟸   ENSRNOT00000100354
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FQ2-F1-model_v2 AlphaFold Q68FQ2 1-310 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695820
Promoter ID:EPDNEW_R6345
Type:initiation region
Name:Jam3_1
Description:junctional adhesion molecule 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0828,208,462 - 28,208,522EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303248 AgrOrtholog
BioCyc Gene G2FUF-31304 BioCyc
Ensembl Genes ENSRNOG00000009149 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055012390 UniProtKB/Swiss-Prot
  ENSRNOG00060026930 UniProtKB/Swiss-Prot
  ENSRNOG00065015326 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012247 ENTREZGENE
  ENSRNOT00000012247.5 UniProtKB/Swiss-Prot
  ENSRNOT00000100354.1 UniProtKB/TrEMBL
  ENSRNOT00000100661.1 UniProtKB/TrEMBL
  ENSRNOT00000101760.1 UniProtKB/TrEMBL
  ENSRNOT00000110398.1 UniProtKB/TrEMBL
  ENSRNOT00055021148 UniProtKB/Swiss-Prot
  ENSRNOT00060046883 UniProtKB/Swiss-Prot
  ENSRNOT00065025504 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114667 IMAGE-MGC_LOAD
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JAM-C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:315509 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94974 IMAGE-MGC_LOAD
NCBI Gene 315509 ENTREZGENE
PANTHER JUNCTIONAL ADHESION MOLECULE C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR44598 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Jam3 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009149 RatGTEx
  ENSRNOG00055012390 RatGTEx
  ENSRNOG00060026930 RatGTEx
  ENSRNOG00065015326 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZL08_RAT UniProtKB/TrEMBL
  A0A8I6AGV1_RAT UniProtKB/TrEMBL
  A0A8I6AII5_RAT UniProtKB/TrEMBL
  A0A8I6ANI6 ENTREZGENE, UniProtKB/TrEMBL
  A6JYE0 ENTREZGENE, UniProtKB/TrEMBL
  JAM3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Jam3  junctional adhesion molecule 3      Symbol and Name status set to approved 1299863 APPROVED
2005-09-30 Jam3        Symbol and Name status set to provisional 70820 PROVISIONAL