Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in increased expression of TACC1 mRNA | CTD | PMID:27840820 | 17beta-estradiol | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [Cycloheximide co-treated with Estradiol] results in decreased expression of TACC1 mRNA and [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TACC1 mRNA | CTD | PMID:15072547 and PMID:19619570 | 17beta-estradiol | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of TACC1 mRNA | CTD | PMID:15072547 more ... | 17beta-estradiol | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Estradiol affects the expression of TACC1 mRNA | CTD | PMID:14699072 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Metribolone results in increased expression of TACC1 mRNA | CTD | PMID:17010196 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TACC1 mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TACC1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TACC1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tacc1 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of TACC1 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TACC1 mRNA | CTD | PMID:19619570 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TACC1 mRNA | CTD | PMID:21346803 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TACC1 mRNA | CTD | PMID:30071829 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TACC1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TACC1 mRNA | CTD | PMID:36041667 | 5-aza-2'-deoxycytidine | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Decitabine affects the expression of TACC1 mRNA | CTD | PMID:23300844 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TACC1 mRNA | CTD | PMID:31881176 | afimoxifene | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | afimoxifene results in decreased expression of TACC1 mRNA and afimoxifene results in decreased expression of TACC1 protein | CTD | PMID:15072547 and PMID:18984771 | afimoxifene | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of TACC1 mRNA] | CTD | PMID:21233418 | aflatoxin B1 | decreases methylation | ISO | TACC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TACC1 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | TACC1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of TACC1 intron | CTD | PMID:30157460 | Aroclor 1254 | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TACC1 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to TACC1 mRNA] | CTD | PMID:32406909 | arsenous acid | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TACC1 mRNA | CTD | PMID:20458559 | belinostat | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | belinostat results in increased expression of TACC1 mRNA | CTD | PMID:19606018 | benzo[a]pyrene | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TACC1 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | affects methylation | ISO | TACC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TACC1 5' UTR more ... | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | Tacc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of TACC1 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TACC1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | beta-hexachlorocyclohexane | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | beta-hexachlorocyclohexane results in decreased expression of TACC1 mRNA | CTD | PMID:25270620 | bis(2-ethylhexyl) phthalate | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of TACC1 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TACC1 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TACC1 mRNA | CTD | PMID:36041667 | bisphenol A | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TACC1 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of TACC1 mRNA | CTD | PMID:36041667 | caffeine | affects phosphorylation | ISO | TACC1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of TACC1 protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | cisplatin | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of TACC1 mRNA | CTD | PMID:23300844 | cisplatin | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TACC1 mRNA | CTD | PMID:27392435 | clofibrate | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of TACC1 mRNA | CTD | PMID:25270620 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of TACC1 mRNA | CTD | PMID:20187946 | copper(II) sulfate | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TACC1 mRNA | CTD | PMID:19549813 | coumarin | decreases phosphorylation | ISO | TACC1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of TACC1 protein | CTD | PMID:35688186 | cycloheximide | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [Cycloheximide co-treated with Estradiol] results in decreased expression of TACC1 mRNA | CTD | PMID:15072547 | cycloheximide | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Cycloheximide results in increased expression of TACC1 mRNA | CTD | PMID:15072547 | cyclosporin A | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TACC1 mRNA | CTD | PMID:25562108 | cyclosporin A | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TACC1 mRNA | CTD | PMID:27989131 | dexamethasone | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TACC1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TACC1 mRNA | CTD | PMID:20458559 | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of TACC1 mRNA | CTD | PMID:33729688 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of TACC1 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TACC1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | entinostat results in increased expression of TACC1 mRNA | CTD | PMID:26272509 and PMID:27188386 | entinostat | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Ethanol results in increased expression of TACC1 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | Tacc1 (Mus musculus) | 6480464 | Ethanol affects the splicing of TACC1 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Fenthion results in decreased expression of TACC1 mRNA | CTD | PMID:34813904 | FR900359 | affects phosphorylation | ISO | TACC1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TACC1 protein | CTD | PMID:37730182 | fulvestrant | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | fulvestrant results in increased expression of TACC1 mRNA and fulvestrant results in increased expression of TACC1 protein | CTD | PMID:15072547 and PMID:18984771 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of TACC1 mRNA | CTD | PMID:25539665 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TACC1 mRNA | CTD | PMID:27387713 | genistein | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Genistein results in decreased expression of TACC1 mRNA | CTD | PMID:21048042 | hydrogen peroxide | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TACC1 mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TACC1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TACC1 protein | CTD | PMID:32959892 | lead(0) | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Lead results in decreased expression of TACC1 mRNA | CTD | PMID:19921347 | lead(0) | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Lead affects the expression of TACC1 mRNA | CTD | PMID:28903495 | lipopolysaccharide | increases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of TACC1 mRNA | CTD | PMID:25890327 | menadione | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of TACC1 mRNA | CTD | PMID:20044591 | mercury dibromide | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of TACC1 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | methidathion | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | methidathion results in decreased expression of TACC1 mRNA | CTD | PMID:34813904 | methyl methanesulfonate | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TACC1 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TACC1 mRNA | CTD | PMID:28001369 | ozone | multiple interactions | ISO | Tacc1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TACC1 mRNA | CTD | PMID:34911549 | panobinostat | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | panobinostat results in increased expression of TACC1 mRNA | CTD | PMID:26272509 | paracetamol | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TACC1 mRNA | CTD | PMID:29067470 | perfluorooctanoic acid | decreases expression | ISO | TACC1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TACC1 protein | CTD | PMID:26879310 | phenobarbital | multiple interactions | ISO | Tacc1 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of TACC1 mRNA] | CTD | PMID:19482888 | phenobarbital | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of TACC1 mRNA | CTD | PMID:19482888 and PMID:25270620 | phenylmercury acetate | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of TACC1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TACC1 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TACC1 mRNA | CTD | PMID:20813756 and PMID:23811191 | propiconazole | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TACC1 mRNA | CTD | PMID:21278054 | raloxifene | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of TACC1 mRNA | CTD | PMID:14699072 | raloxifene | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA | CTD | PMID:19059307 | SB 431542 | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Silver results in increased expression of TACC1 mRNA | CTD | PMID:26551752 | silver(0) | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Silver results in increased expression of TACC1 mRNA | CTD | PMID:26551752 | sodium arsenate | increases expression | ISO | Tacc1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of TACC1 mRNA | CTD | PMID:21795629 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of TACC1 mRNA | CTD | PMID:22561333 | tamoxifen | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA | CTD | PMID:19059307 | tamoxifen | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Tamoxifen affects the expression of TACC1 mRNA | CTD | PMID:14699072 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TACC1 mRNA | CTD | PMID:34492290 | torcetrapib | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of TACC1 mRNA | CTD | PMID:23228038 | trichostatin A | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TACC1 mRNA | CTD | PMID:19606018 more ... | trichostatin A | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | tungsten | decreases expression | ISO | Tacc1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of TACC1 mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | TACC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TACC1 gene | CTD | PMID:29154799 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of TACC1 mRNA | CTD | PMID:29427782 | valproic acid | affects expression | ISO | TACC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TACC1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | TACC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACC1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TACC1 mRNA | CTD | PMID:23179753 more ... | vorinostat | increases expression | ISO | TACC1 (Homo sapiens) | 6480464 | vorinostat results in increased expression of TACC1 mRNA | CTD | PMID:22083351 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
