Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Ablim2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ABLIM2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABLIM2 mRNA] | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ABLIM2 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of ABLIM2 mRNA | CTD | PMID:20660070 and PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ABLIM2 mRNA | CTD | PMID:32109520 and PMID:33387578 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Ablim2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ABLIM2 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | decreases methylation | ISO | Ablim2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased methylation of ABLIM2 promoter | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABLIM2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ABLIM2 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Ablim2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of ABLIM2 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ABLIM2 mRNA | CTD | PMID:24780913 and PMID:30047161 | 8-Br-cAMP | increases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of ABLIM2 mRNA | CTD | PMID:22079614 | aflatoxin B1 | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ABLIM2 mRNA | CTD | PMID:22100608 | aflatoxin B1 | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ABLIM2 3' UTR more ... | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ABLIM2 3' UTR and aflatoxin B2 results in increased methylation of ABLIM2 intron | CTD | PMID:30157460 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ABLIM2 mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ABLIM2 mRNA | CTD | PMID:24449571 | arsane | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABLIM2 gene | CTD | PMID:25304211 | arsane | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ABLIM2 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ABLIM2 mRNA | CTD | PMID:32525701 | arsenic atom | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABLIM2 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of ABLIM2 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ABLIM2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ABLIM2 3' UTR and Benzo(a)pyrene affects the methylation of ABLIM2 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases expression | ISO | Ablim2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ABLIM2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Ablim2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ABLIM2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ABLIM2 mRNA] and Benzo(a)pyrene promotes the reaction [AHR protein binds to ABLIM2 promoter] | CTD | PMID:19654925 and PMID:22228805 | benzo[e]pyrene | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of ABLIM2 intron | CTD | PMID:30157460 | benzo[e]pyrene | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of ABLIM2 exon | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ABLIM2 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ABLIM2 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABLIM2 mRNA | CTD | PMID:28628672 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of ABLIM2 protein | CTD | PMID:28903499 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of ABLIM2 mRNA | CTD | PMID:19167457 | chlorpyrifos | decreases expression | ISO | Ablim2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ABLIM2 mRNA | CTD | PMID:32715474 | chlorpyrifos | increases expression | ISO | Ablim2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ABLIM2 mRNA | CTD | PMID:37019170 | clozapine | increases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Clozapine results in increased expression of ABLIM2 mRNA | CTD | PMID:17346280 | dexamethasone | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABLIM2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ABLIM2 mRNA | CTD | PMID:28628672 | ethanol | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of ABLIM2 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABLIM2 mRNA] | CTD | PMID:22206623 | indometacin | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABLIM2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ABLIM2 mRNA | CTD | PMID:28628672 | iron dichloride | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of ABLIM2 mRNA | CTD | PMID:35984750 | lead(0) | affects expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Lead affects the expression of ABLIM2 mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of ABLIM2 mRNA | CTD | PMID:35811015 | maneb | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of ABLIM2 mRNA | CTD | PMID:36117858 | methapyrilene | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of ABLIM2 exon | CTD | PMID:30157460 | methapyrilene | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of ABLIM2 intron | CTD | PMID:30157460 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ABLIM2 mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ABLIM2 gene | CTD | PMID:35440735 | mono(2-ethylhexyl) phthalate | increases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of ABLIM2 mRNA | CTD | PMID:36314267 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ABLIM2 gene | CTD | PMID:33148267 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of ABLIM2 protein | CTD | PMID:33146391 | paracetamol | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ABLIM2 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ABLIM2 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of ABLIM2 mRNA | CTD | PMID:32680482 | paraquat | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in increased expression of ABLIM2 mRNA | CTD | PMID:36117858 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ABLIM2 gene | CTD | PMID:33148267 | phenobarbital | affects expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of ABLIM2 mRNA | CTD | PMID:19159669 | pioglitazone | multiple interactions | ISO | Ablim2 (Mus musculus) | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABLIM2 mRNA | CTD | PMID:27935865 | progesterone | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ABLIM2 mRNA | CTD | PMID:20660070 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of ABLIM2 mRNA | CTD | PMID:35811015 | silicon dioxide | affects expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Silicon Dioxide analog affects the expression of ABLIM2 mRNA | CTD | PMID:25895662 | sodium arsenate | multiple interactions | ISO | ABLIM2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ABLIM2 mRNA | CTD | PMID:32525701 | sodium arsenite | affects methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of ABLIM2 gene | CTD | PMID:28589171 | sodium arsenite | increases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ABLIM2 mRNA | CTD | PMID:29301061 | sulforaphane | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of ABLIM2 mRNA | CTD | PMID:31838189 | sunitinib | increases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ABLIM2 mRNA | CTD | PMID:31533062 | toluene | decreases expression | ISO | ABLIM2 (Homo sapiens) | 6480464 | Toluene results in decreased expression of ABLIM2 mRNA | CTD | PMID:26717081 | toluene | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Toluene results in increased methylation of ABLIM2 gene | CTD | PMID:26717081 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ABLIM2 mRNA | CTD | PMID:33387578 | trimellitic anhydride | decreases expression | ISO | Ablim2 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of ABLIM2 mRNA | CTD | PMID:19042947 | triptonide | affects expression | ISO | Ablim2 (Mus musculus) | 6480464 | triptonide affects the expression of ABLIM2 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | ABLIM2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ABLIM2 gene | CTD | PMID:29154799 | |