St8sia5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5) - Rat Genome Database

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Gene: St8sia5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5) Rattus norvegicus
Analyze
Symbol: St8sia5
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
RGD ID: 1302934
Description: Enables sialyltransferase activity. Involved in glycosphingolipid biosynthetic process. Located in Golgi membrane. Orthologous to human ST8SIA5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5); PARTICIPATES IN ganglioside metabolic pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-2,8-sialyltransferase; alpha-2,8-sialyltransferase 8E; SATV; sialyltransferase 8E; sialyltransferase St8Sia V; SIAT8-E; SIAT8E; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5; ST8SiaV
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81873,010,235 - 73,072,984 (+)NCBIGRCr8
mRatBN7.21870,736,395 - 70,802,537 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,736,602 - 70,797,789 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1872,839,313 - 72,900,072 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01873,508,522 - 73,569,285 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01871,365,117 - 71,425,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01873,564,010 - 73,630,256 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,564,247 - 73,625,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01873,242,401 - 73,305,796 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41874,163,989 - 74,224,969 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11874,237,261 - 74,298,242 (+)NCBI
Celera1869,258,554 - 69,319,155 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The c-series gangliosides GT3, GT2 and GP1c are formed in rat liver Golgi by the same set of glycosyltransferases that catalyse the biosynthesis of asialo-, a- and b-series gangliosides. Iber H, etal., Glycobiology. 1992 Apr;2(2):137-42. doi: 10.1093/glycob/2.2.137.
3. Molecular cloning and expression of a fifth type of alpha2,8-sialyltransferase (ST8Sia V). Its substrate specificity is similar to that of SAT-V/III, which synthesize GD1c, GT1a, GQ1b and GT3. Kono M, etal., J Biol Chem 1996 Nov 15;271(46):29366-71.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15843597   PMID:19103603  


Genomics

Comparative Map Data
St8sia5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81873,010,235 - 73,072,984 (+)NCBIGRCr8
mRatBN7.21870,736,395 - 70,802,537 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,736,602 - 70,797,789 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1872,839,313 - 72,900,072 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01873,508,522 - 73,569,285 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01871,365,117 - 71,425,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01873,564,010 - 73,630,256 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,564,247 - 73,625,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01873,242,401 - 73,305,796 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41874,163,989 - 74,224,969 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11874,237,261 - 74,298,242 (+)NCBI
Celera1869,258,554 - 69,319,155 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
ST8SIA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381846,667,821 - 46,757,053 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1846,667,821 - 46,759,257 (-)EnsemblGRCh38hg38GRCh38
GRCh371844,247,784 - 44,337,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,513,079 - 42,591,037 (-)NCBINCBI36Build 36hg18NCBI36
Build 341842,513,078 - 42,591,037NCBI
Celera1841,066,687 - 41,144,720 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1841,116,714 - 41,194,741 (-)NCBIHuRef
CHM1_11844,186,081 - 44,264,162 (-)NCBICHM1_1
T2T-CHM13v2.01846,858,373 - 46,947,691 (-)NCBIT2T-CHM13v2.0
St8sia5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391877,273,529 - 77,343,146 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1877,273,535 - 77,346,467 (+)EnsemblGRCm39 Ensembl
GRCm381877,185,847 - 77,255,450 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1877,185,839 - 77,258,771 (+)EnsemblGRCm38mm10GRCm38
MGSCv371877,424,586 - 77,494,189 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361877,390,303 - 77,459,770 (+)NCBIMGSCv36mm8
MGSCv361877,608,620 - 77,678,315 (+)NCBIMGSCv36mm8
Celera1878,368,567 - 78,438,780 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1852.13NCBI
St8sia5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540232,165,912 - 32,232,674 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540232,165,912 - 32,232,683 (-)NCBIChiLan1.0ChiLan1.0
ST8SIA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21764,081,658 - 64,186,102 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11849,774,259 - 49,878,701 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01839,958,239 - 40,036,282 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11843,492,025 - 43,569,857 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1843,492,025 - 43,569,857 (-)Ensemblpanpan1.1panPan2
ST8SIA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1744,583,638 - 44,656,823 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl744,591,092 - 44,646,048 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha744,075,723 - 44,139,749 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0744,545,565 - 44,602,115 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl744,545,565 - 44,598,988 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1744,245,521 - 44,309,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0744,299,526 - 44,363,613 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0744,583,294 - 44,647,319 (+)NCBIUU_Cfam_GSD_1.0
St8sia5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494440,859,884 - 40,935,220 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936517186,452 - 253,513 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936517186,465 - 262,622 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST8SIA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl196,297,034 - 96,375,868 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1196,291,794 - 96,375,909 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ST8SIA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11834,139,529 - 34,229,582 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1834,140,253 - 34,228,664 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660508,512,190 - 8,600,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St8sia5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477810,305,450 - 10,389,625 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477810,293,685 - 10,390,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in St8sia5
311 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:66
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000035317
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647871893566Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat

Markers in Region
D18Got76  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,752,029 - 70,752,174 (+)MAPPERmRatBN7.2
Rnor_6.01873,579,677 - 73,579,821NCBIRnor6.0
Rnor_5.01873,258,033 - 73,258,177UniSTSRnor5.0
RGSC_v3.41874,179,366 - 74,179,511RGDRGSC3.4
RGSC_v3.41874,179,367 - 74,179,511UniSTSRGSC3.4
RGSC_v3.11874,252,640 - 74,252,784RGD
Celera1869,273,968 - 69,274,112UniSTS
RH 3.4 Map18755.8UniSTS
RH 3.4 Map18755.8RGD
RH 2.0 Map18164.4RGD
Cytogenetic Map18q12.3UniSTS
X98014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,797,582 - 70,797,704 (+)MAPPERmRatBN7.2
Rnor_6.01873,625,218 - 73,625,339NCBIRnor6.0
Rnor_5.01873,303,102 - 73,303,223UniSTSRnor5.0
RGSC_v3.41874,225,246 - 74,225,367UniSTSRGSC3.4
Celera1869,319,432 - 69,319,553UniSTS
Cytogenetic Map18q12.3UniSTS
RH139949  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,797,324 - 70,797,538 (+)MAPPERmRatBN7.2
Rnor_6.01873,624,960 - 73,625,173NCBIRnor6.0
Rnor_5.01873,302,844 - 73,303,057UniSTSRnor5.0
RGSC_v3.41874,224,988 - 74,225,201UniSTSRGSC3.4
Celera1869,319,174 - 69,319,387UniSTS
RH 3.4 Map18747.0UniSTS
Cytogenetic Map18q12.3UniSTS
BF416672  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,771,601 - 70,771,851 (+)MAPPERmRatBN7.2
Rnor_6.01873,599,245 - 73,599,494NCBIRnor6.0
Rnor_5.01873,277,807 - 73,278,056UniSTSRnor5.0
RGSC_v3.41874,198,935 - 74,199,184UniSTSRGSC3.4
Celera1869,293,515 - 69,293,764UniSTS
RH 3.4 Map18745.3UniSTS
Cytogenetic Map18q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 25 2
Low 36 8 8 8 31 24 1 8
Below cutoff 1 7 11 8 7 8 18 27 15 10

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000035317   ⟹   ENSRNOP00000033363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,736,602 - 70,797,789 (+)Ensembl
Rnor_6.0 Ensembl1873,564,312 - 73,624,941 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077679   ⟹   ENSRNOP00000069340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,736,602 - 70,797,789 (+)Ensembl
Rnor_6.0 Ensembl1873,564,247 - 73,625,137 (+)Ensembl
RefSeq Acc Id: NM_001413108   ⟹   NP_001400037
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,011,587 - 73,072,984 (+)NCBI
mRatBN7.21870,736,395 - 70,797,802 (+)NCBI
RefSeq Acc Id: NM_213628   ⟹   NP_998793
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,011,587 - 73,072,984 (+)NCBI
mRatBN7.21870,736,395 - 70,797,802 (+)NCBI
Rnor_6.01873,564,312 - 73,624,941 (+)NCBI
Rnor_5.01873,242,401 - 73,305,796 (+)NCBI
RGSC_v3.41874,163,989 - 74,224,969 (+)RGD
Celera1869,258,554 - 69,319,155 (+)RGD
Sequence:
RefSeq Acc Id: XM_039097011   ⟹   XP_038952939
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,011,856 - 73,072,984 (+)NCBI
mRatBN7.21870,736,632 - 70,800,277 (+)NCBI
RefSeq Acc Id: XM_039097012   ⟹   XP_038952940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,010,235 - 73,072,984 (+)NCBI
mRatBN7.21870,736,636 - 70,800,277 (+)NCBI
RefSeq Acc Id: XM_039097013   ⟹   XP_038952941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,038,219 - 73,072,984 (+)NCBI
mRatBN7.21870,757,715 - 70,802,537 (+)NCBI
RefSeq Acc Id: XM_039097015   ⟹   XP_038952943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,038,223 - 73,072,984 (+)NCBI
mRatBN7.21870,757,716 - 70,802,537 (+)NCBI
RefSeq Acc Id: XM_063277495   ⟹   XP_063133565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,032,885 - 73,072,984 (+)NCBI
RefSeq Acc Id: XM_063277496   ⟹   XP_063133566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,032,888 - 73,072,984 (+)NCBI
RefSeq Acc Id: XM_063277497   ⟹   XP_063133567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81873,032,888 - 73,072,984 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_998793   ⟸   NM_213628
- Peptide Label: isoform 2
- UniProtKB: Q6ZXC8 (UniProtKB/Swiss-Prot),   A0A0G2JV41 (UniProtKB/Swiss-Prot),   E9PU47 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069340   ⟸   ENSRNOT00000077679
RefSeq Acc Id: ENSRNOP00000033363   ⟸   ENSRNOT00000035317
RefSeq Acc Id: XP_038952939   ⟸   XM_039097011
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952940   ⟸   XM_039097012
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952941   ⟸   XM_039097013
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038952943   ⟸   XM_039097015
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001400037   ⟸   NM_001413108
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063133565   ⟸   XM_063277495
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133566   ⟸   XM_063277496
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063133567   ⟸   XM_063277497
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6ZXC8-F1-model_v2 AlphaFold Q6ZXC8 1-376 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1302934 AgrOrtholog
BioCyc Gene G2FUF-6944 BioCyc
Ensembl Genes ENSRNOG00000022691 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055013714 UniProtKB/Swiss-Prot
  ENSRNOG00060014815 UniProtKB/Swiss-Prot
  ENSRNOG00065023541 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000035317 ENTREZGENE
  ENSRNOT00000035317.2 UniProtKB/Swiss-Prot
  ENSRNOT00000077679 ENTREZGENE
  ENSRNOT00000077679.2 UniProtKB/Swiss-Prot
  ENSRNOT00055023570 UniProtKB/Swiss-Prot
  ENSRNOT00060025340 UniProtKB/Swiss-Prot
  ENSRNOT00065040296 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.1480.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/Swiss-Prot
KEGG Report rno:364901 UniProtKB/Swiss-Prot
NCBI Gene 364901 ENTREZGENE
PANTHER ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALPHA-2,8-SIALYLTRANSFERASE 8E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen St8sia5 PhenoGen
PIRSF Sialyl_trans UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000022691 RatGTEx
  ENSRNOG00055013714 RatGTEx
  ENSRNOG00060014815 RatGTEx
  ENSRNOG00065023541 RatGTEx
UniProt A0A0G2JV41 ENTREZGENE
  A6KMU7_RAT UniProtKB/TrEMBL
  A6KMU9_RAT UniProtKB/TrEMBL
  E9PU47 ENTREZGENE
  Q6ZXC8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A0G2JV41 UniProtKB/Swiss-Prot
  E9PU47 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-05 St8sia5  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5  St8sia5  ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-15 St8sia5  ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 5  St8sia5  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 St8sia5  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5  SIAT8E  alpha-2,8-sialyltransferase  Symbol and Name updated 1299863 APPROVED
2005-02-14 SIAT8E  alpha-2,8-sialyltransferase      Symbol and Name status set to provisional 70820 PROVISIONAL