Wdr87 (WD repeat domain 87) - Rat Genome Database

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Gene: Wdr87 (WD repeat domain 87) Rattus norvegicus
Analyze
Symbol: Wdr87
Name: WD repeat domain 87
RGD ID: 9407641
Description: ASSOCIATED WITH genetic disease (ortholog); INTERACTS WITH atrazine; bisphenol A; (+)-catechin (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NEWGENE_1585333; WD repeat domain 87 like; WD repeat-containing protein 87; Wdr87l
RGD Orthologs
Human
Mouse
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8193,953,766 - 93,972,787 (+)NCBIGRCr8
mRatBN7.2184,826,282 - 84,845,693 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0187,477,200 - 87,479,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Wdr87
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8193,953,766 - 93,972,787 (+)NCBIGRCr8
mRatBN7.2184,826,282 - 84,845,693 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0187,477,200 - 87,479,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Cytogenetic Map1q21NCBI
WDR87
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381937,884,823 - 37,906,697 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1937,884,823 - 37,906,677 (-)EnsemblGRCh38hg38GRCh38
GRCh371938,375,463 - 38,397,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,067,412 - 43,089,157 (-)NCBINCBI36Build 36hg18NCBI36
Celera1935,176,408 - 35,198,258 (-)NCBICelera
Cytogenetic Map19q13.13NCBI
HuRef1934,824,144 - 34,845,978 (-)NCBIHuRef
CHM1_11938,375,845 - 38,397,697 (-)NCBICHM1_1
T2T-CHM13v2.01940,686,877 - 40,708,749 (-)NCBIT2T-CHM13v2.0
Wdr87-ps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,218,688 - 29,237,289 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,223,968 - 29,237,289 (+)EnsemblGRCm39 Ensembl
GRCm38729,519,253 - 29,537,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,524,543 - 29,538,055 (+)EnsemblGRCm38mm10GRCm38
MGSCv37730,309,562 - 30,323,074 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,245,476 - 29,246,815 (+)NCBIMGSCv36mm8
Celera724,095,668 - 24,109,094 (+)NCBICelera
Cytogenetic Map7B1NCBI
WDR87
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl646,889,873 - 46,908,296 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1646,890,026 - 46,901,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
WDR87
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1632,524,249 - 32,548,462 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl632,524,395 - 32,538,379 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607310,465,108 - 10,488,965 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr87
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479411,448,899 - 11,454,270 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wdr87
81 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_063280682   ⟹   XP_063136752
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8193,953,766 - 93,972,787 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063136752 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_063136752   ⟸   XM_063280682


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:9407641 AgrOrtholog
BioCyc Gene G2FUF-60180 BioCyc
NCBI Gene Wdr87 ENTREZGENE
PhenoGen Wdr87 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-04 Wdr87  WD repeat domain 87  Wdr87l  WD repeat domain 87 like  Name and Symbol changed 629549 APPROVED
2018-03-16 Wdr87l  WD repeat domain 87 like  NEWGENE_1585333  WD repeat domain 87  Name and Symbol changed 629549 APPROVED