Mrpl42l1 (mitochondrial ribosomal protein L42 like 1) - Rat Genome Database

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Gene: Mrpl42l1 (mitochondrial ribosomal protein L42 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mrpl42l1 (Ensembl: LOC103691922)
Name: mitochondrial ribosomal protein L42 like 1 (Ensembl:28S ribosomal protein L42, mitochondrial)
RGD ID: 9333559
Description: Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Orthologous to human MRPL42 (mitochondrial ribosomal protein L42).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: 28S ribosomal protein L42, mitochondrial; 28S ribosomal protein S32, mitochondrial; L42mt; large ribosomal subunit protein mL42; LOC103691922; MRP-L42; MRP-S32; Mrpl42; S32mt
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81350,195,710 - 50,196,366 (+)NCBIGRCr8
mRatBN7.21347,644,007 - 47,644,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl730,117,977 - 30,141,639 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1347,644,118 - 47,644,543 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01353,067,440 - 53,067,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1353,067,484 - 53,067,909 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1347,956,559 - 47,957,068 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:9857009   PMID:15057822  


Genomics

Variants

.
Variants in Mrpl42l1
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000011332
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134343790447841255Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134372077062022792Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134522835847841255Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 2 1 1 1
Low 1 2 2 1 2 1 5 1
Below cutoff 5 7 4 3 4 3 3 11 7 11 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1347,644,118 - 47,644,543 (+)Ensembl
Rnor_6.0 Ensembl1353,067,484 - 53,067,909 (+)Ensembl
RefSeq Acc Id: NM_001409050   ⟹   NP_001395979
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81350,195,710 - 50,196,366 (+)NCBI
mRatBN7.21347,644,007 - 47,644,663 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001395979 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089606.1
  ENSRNOP00000089938
  ENSRNOP00000089938.1
  ENSRNOP00000097581.1
GenBank Protein P0C2B9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001395979   ⟸   NM_001409050
- UniProtKB: P0C2B9 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C2B9-F1-model_v2 AlphaFold P0C2B9 1-141 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:9333559 AgrOrtholog
BioCyc Gene G2FUF-18181 BioCyc
Ensembl Genes ENSRNOG00000025964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000042740 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011332 ENTREZGENE
  ENSRNOT00000011332.7 UniProtKB/Swiss-Prot
  ENSRNOT00000102630.1 UniProtKB/TrEMBL
  ENSRNOT00000118711.1 UniProtKB/TrEMBL
InterPro MRPL42 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene LOC103691922 ENTREZGENE
PANTHER 39S RIBOSOMAL PROTEIN L42, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam MRP-S32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mrpl42l1 PhenoGen
RatGTEx ENSRNOG00000025964 RatGTEx
  ENSRNOG00000042740 RatGTEx
UniProt A0A8I6A7N4_RAT UniProtKB/TrEMBL
  A0A8I6AV60_RAT UniProtKB/TrEMBL
  P0C2B9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Mrpl42l1  mitochondrial ribosomal protein L42 like 1  LOC103691922  28S ribosomal protein L42, mitochondrial  Symbol and Name Changed 1299863 APPROVED
2014-08-25 LOC103691922  28S ribosomal protein L42, mitochondrial      Symbol and Name status set to provisional 70820 PROVISIONAL