Thpo (thrombopoietin) - Rat Genome Database

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Gene: Thpo (thrombopoietin) Chinchilla lanigera
Analyze
Symbol: Thpo
Name: thrombopoietin
RGD ID: 9060925
Description: INVOLVED IN cell surface receptor signaling pathway via STAT (ortholog); megakaryocyte development (ortholog); megakaryocyte differentiation (ortholog); ASSOCIATED WITH 3-Methylcrotonyl-CoA carboxylase 1 deficiency (ortholog); aplastic anemia (ortholog); arteriosclerosis obliterans (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,123,637 - 23,129,198 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Thpo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,123,637 - 23,129,198 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBIChiLan1.0ChiLan1.0
THPO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,371,935 - 184,379,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3184,371,935 - 184,381,968 (-)EnsemblGRCh38hg38GRCh38
GRCh373184,089,723 - 184,097,476 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,572,467 - 185,578,626 (-)NCBINCBI36Build 36hg18NCBI36
Build 343185,572,474 - 185,578,634NCBI
Celera3182,530,743 - 182,536,902 (-)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,496,308 - 181,502,467 (-)NCBIHuRef
CHM1_13184,054,230 - 184,060,389 (-)NCBICHM1_1
T2T-CHM13v2.03187,181,188 - 187,188,943 (-)NCBIT2T-CHM13v2.0
Thpo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,543,204 - 20,553,261 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,543,204 - 20,553,261 (-)EnsemblGRCm39 Ensembl
GRCm381620,724,454 - 20,734,511 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,724,454 - 20,734,511 (-)EnsemblGRCm38mm10GRCm38
MGSCv371620,724,527 - 20,734,584 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,637,997 - 20,648,054 (-)NCBIMGSCv36mm8
Celera1621,289,807 - 21,299,861 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1612.51NCBI
Thpo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2 Ensembl1180,182,820 - 80,188,167 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01182,845,676 - 82,853,439 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,848,853 - 82,852,425 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,868,655 - 83,873,910 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,925,385 - 85,932,532 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,412,552 - 82,417,807NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1179,022,653 - 79,027,908 (+)NCBICelera
RH 3.4 Map11 RGD
Cytogenetic Map11q23NCBI
THPO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22182,243,453 - 182,252,794 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13182,246,427 - 182,257,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,409,038 - 181,416,986 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,891,025 - 189,897,429 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,891,025 - 189,897,429 (-)Ensemblpanpan1.1panPan2
THPO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,245,006 - 17,255,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,247,731 - 17,253,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3421,330,370 - 21,340,784 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03417,152,310 - 17,162,724 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,155,818 - 17,159,897 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13417,189,183 - 17,199,597 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03417,185,251 - 17,195,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03417,414,218 - 17,424,632 (-)NCBIUU_Cfam_GSD_1.0
Thpo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602119,414,449 - 119,423,408 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365785,509,111 - 5,515,103 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365785,508,669 - 5,515,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THPO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,260,215 - 122,267,860 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113122,259,654 - 122,267,860 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,750,641 - 131,757,108 (-)NCBISscrofa10.2Sscrofa10.2susScr3
THPO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,040,684 - 5,048,387 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606313,818,626 - 13,825,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Thpo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473072,212,423 - 72,219,485 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473072,210,880 - 72,218,615 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000019922   ⟹   ENSCLAP00000019729
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542023,123,637 - 23,129,198 (+)Ensembl
RefSeq Acc Id: XM_005383308   ⟹   XP_005383365
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005383309   ⟹   XP_005383366
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005383310   ⟹   XP_005383367
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513327   ⟹   XP_013368781
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513328   ⟹   XP_013368782
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513329   ⟹   XP_013368783
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542023,120,828 - 23,128,894 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005383365   ⟸   XM_005383308
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VX50 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383366   ⟸   XM_005383309
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005383367   ⟸   XM_005383310
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013368781   ⟸   XM_013513327
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013368782   ⟸   XM_013513328
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013368783   ⟸   XM_013513329
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000019729   ⟸   ENSCLAT00000019922


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013534 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019922 ENTREZGENE
  ENSCLAT00000019922.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  EPO_TPO UniProtKB/TrEMBL
  Thrombopoietin UniProtKB/TrEMBL
NCBI Gene Thpo ENTREZGENE
PANTHER PTHR10560 UniProtKB/TrEMBL
  THROMBOPOIETIN UniProtKB/TrEMBL
Pfam EPO_TPO UniProtKB/TrEMBL
PRINTS THROMBOPTN UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A8C2VX50 ENTREZGENE, UniProtKB/TrEMBL