Adcy4 (adenylate cyclase 4) - Rat Genome Database

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Gene: Adcy4 (adenylate cyclase 4) Chinchilla lanigera
Analyze
Symbol: Adcy4
Name: adenylate cyclase 4
RGD ID: 9056035
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); protein kinase C binding (ortholog); INVOLVED IN adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cAMP biosynthetic process (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; protein kinase A (PKA) signaling pathway; ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); lysinuric protein intolerance (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate cyclase type 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540935,966,332 - 35,982,218 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540935,966,529 - 35,982,839 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adcy4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540935,966,332 - 35,982,218 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540935,966,529 - 35,982,839 (+)NCBIChiLan1.0ChiLan1.0
ADCY4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,318,359 - 24,335,071 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,318,349 - 24,335,093 (-)EnsemblGRCh38hg38GRCh38
GRCh371424,787,565 - 24,804,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,857,410 - 23,873,704 (-)NCBINCBI36Build 36hg18NCBI36
Build 341423,857,410 - 23,873,704NCBI
Celera144,652,191 - 4,668,489 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,902,443 - 4,919,171 (-)NCBIHuRef
CHM1_11424,786,147 - 24,802,872 (-)NCBICHM1_1
T2T-CHM13v2.01418,516,694 - 18,533,416 (-)NCBIT2T-CHM13v2.0
Adcy4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391456,006,513 - 56,021,552 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1456,006,514 - 56,021,552 (-)EnsemblGRCm39 Ensembl
GRCm381455,769,056 - 55,784,095 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,769,057 - 55,784,095 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,387,929 - 56,402,856 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,723,163 - 54,738,090 (-)NCBIMGSCv36mm8
Celera1453,574,126 - 53,589,052 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Adcy4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81533,236,201 - 33,252,070 (-)NCBIGRCr8
mRatBN7.21529,266,280 - 29,282,153 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,266,287 - 29,282,108 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1531,111,969 - 31,127,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01532,259,179 - 32,274,998 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,501,528 - 30,517,347 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,453,917 - 34,469,779 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,453,915 - 34,469,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,342,429 - 38,358,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,930,531 - 33,946,352 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,946,233 - 33,962,015 (-)NCBI
Celera1528,841,216 - 28,857,037 (-)NCBICelera
Cytogenetic Map15p13NCBI
ADCY4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,673,520 - 25,690,270 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,890,012 - 24,906,738 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,094,899 - 5,111,603 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11423,218,178 - 23,234,861 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,218,178 - 23,234,861 (-)Ensemblpanpan1.1panPan2
ADCY4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,288,708 - 4,304,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,288,714 - 4,304,589 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,210,485 - 4,226,167 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,399,506 - 4,415,189 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,399,531 - 4,415,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.184,089,855 - 4,105,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.084,151,682 - 4,167,531 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,414,264 - 4,429,941 (-)NCBIUU_Cfam_GSD_1.0
Adcy4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,158,190 - 36,175,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722213,916 - 230,906 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722213,916 - 230,802 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl774,956,220 - 74,972,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1774,955,410 - 74,972,440 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,226,295 - 80,243,376 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,301,445 - 1,318,171 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,301,506 - 1,316,868 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,985,965 - 13,001,961 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,169,816 - 8,189,168 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,170,258 - 8,186,214 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022530   ⟹   ENSCLAP00000022325
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540935,966,332 - 35,982,218 (+)Ensembl
RefSeq Acc Id: XM_005377013   ⟹   XP_005377070
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540935,966,529 - 35,982,839 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377070 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022325
  ENSCLAP00000022325.1
Reference Protein Sequences
RefSeq Acc Id: XP_005377070   ⟸   XM_005377013
- UniProtKB: A0A8C2YTK7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022325   ⟸   ENSCLAT00000022530
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022530 ENTREZGENE
  ENSCLAT00000022530.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1230 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  AC_N UniProtKB/TrEMBL
  Adcy UniProtKB/TrEMBL
  Adcy_conserved_dom UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Adcy4 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
  ADENYLATE CYCLASE TYPE 4 UniProtKB/TrEMBL
Pfam AC_N UniProtKB/TrEMBL
  DUF1053 UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/TrEMBL
PIRSF Ade_cyc UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF55073 UniProtKB/TrEMBL
UniProt A0A8C2YTK7 ENTREZGENE, UniProtKB/TrEMBL