Psen2 (presenilin 2) - Rat Genome Database

Name: Psen2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Psen2 (presenilin 2) Chinchilla lanigera

Analyze

Symbol:

Psen2

Name:

presenilin 2

RGD ID:

9045523

Description:

ENCODES a protein that exhibits aspartic endopeptidase activity, intramembrane cleaving (ortholog); endopeptidase activity (ortholog); INVOLVED IN amyloid precursor protein catabolic process (ortholog); amyloid-beta formation (ortholog); amyloid-beta metabolic process (ortholog); PARTICIPATES IN altered Notch signaling pathway involving the macromolecules modifying the main players; Alzheimer's disease pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 4 (ortholog); asphyxia neonatorum (ortholog); FOUND IN centrosome (ortholog); ciliary basal body (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

presenilin-2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSEN2 (presenilin 2)	NCBI	Ortholog
Mus musculus (house mouse):	Psen2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Psen2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSEN2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSEN2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psen2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSEN2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSEN2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psen2 (presenilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	5,727,367 - 5,752,234 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	5,727,367 - 5,748,798 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Alzheimer's disease 4 (ISO)

asphyxia neonatorum (ISO)

breast cancer (ISO)

COVID-19 (ISO)

dilated cardiomyopathy (ISO)

dilated cardiomyopathy 1V (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Huntington's Disease-Like Syndrome (ISO)

parathyroid carcinoma (ISO)

Presenile and Senile Dementia (ISO)

pulmonary fibrosis (ISO)

Pulmonary Hemorrhage (ISO)

vascular dementia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amyloid precursor protein catabolic process (ISO)

amyloid-beta formation (ISO)

amyloid-beta metabolic process (ISO)

apoptotic signaling pathway (ISO)

brain morphogenesis (ISO)

calcium ion transport (ISO)

cardiac muscle contraction (ISO)

cell fate specification (ISO)

dorsal/ventral neural tube patterning (ISO)

embryonic limb morphogenesis (ISO)

endoplasmic reticulum calcium ion homeostasis (ISO)

forebrain development (ISO)

hair follicle development (ISO)

hematopoietic progenitor cell differentiation (ISO)

learning or memory (ISO)

locomotion (ISO)

lung alveolus development (ISO)

membrane protein ectodomain proteolysis (ISO)

memory (ISO)

mitochondrion-endoplasmic reticulum membrane tethering (ISO)

myeloid leukocyte differentiation (ISO)

negative regulation of apoptotic signaling pathway (ISO)

negative regulation of protein phosphorylation (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of ubiquitin-dependent protein catabolic process (ISO)

neuroinflammatory response (ISO)

neuron cellular homeostasis (ISO)

Notch signaling pathway (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of coagulation (ISO)

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (ISO)

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO)

positive regulation of receptor recycling (ISO)

protein catabolic process at postsynapse (ISO)

protein maturation (ISO)

protein metabolic process (ISO)

protein processing (ISO)

protein transport (ISO)

regulation of calcium import into the mitochondrion (ISO)

regulation of postsynapse organization (ISO)

regulation of synaptic plasticity (ISO)

response to hypoxia (ISO)

skin morphogenesis (ISO)

somitogenesis (ISO)

T cell activation involved in immune response (ISO)

T cell receptor signaling pathway (ISO)

thymus development (ISO)

Cellular Component

centrosome (ISO)

ciliary basal body (ISO)

cytosol (ISO)

early endosome (ISO)

endoplasmic reticulum (ISO)

gamma-secretase complex (ISO)

glutamatergic synapse (ISO)

Golgi apparatus (ISO)

kinetochore (ISO)

membrane (ISO)

neuronal cell body (ISO)

nuclear inner membrane (ISO)

plasma membrane (ISO)

presynaptic membrane (ISO)

protein-containing complex (ISO)

synaptic membrane (ISO)

synaptic vesicle (ISO)

Z disc (ISO)

Molecular Function

aspartic endopeptidase activity, intramembrane cleaving (ISO)

endopeptidase activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

altered Notch signaling pathway involving the macromolecules modifying the main players (ISO)

Alzheimer's disease pathway (ISO)

Notch signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Psen2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	5,727,367 - 5,752,234 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	5,727,367 - 5,748,798 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSEN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	226,870,616 - 226,903,668 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	226,870,184 - 226,927,726 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	227,058,317 - 227,083,799 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	225,124,896 - 225,150,427 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	223,365,694 - 223,390,532	NCBI
Celera	1	200,249,068 - 200,274,610 (+)	NCBI		Celera
Cytogenetic Map	1	q42.13	NCBI
HuRef	1	197,575,178 - 197,600,711 (+)	NCBI		HuRef
CHM1_1	1	228,331,030 - 228,356,564 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	226,058,503 - 226,091,743 (+)	NCBI		T2T-CHM13v2.0

Psen2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	180,054,569 - 180,091,030 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	180,054,569 - 180,091,003 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	180,227,004 - 180,263,467 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	180,227,004 - 180,263,438 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	182,157,135 - 182,186,431 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	182,063,681 - 182,082,576 (-)	NCBI		MGSCv36	mm8
Celera	1	187,291,668 - 187,320,266 (-)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	84.19	NCBI

Psen2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	94,499,451 - 94,528,419 (-)	NCBI		GRCr8
mRatBN7.2	13	91,967,506 - 91,993,240 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	91,967,983 - 91,993,174 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	94,473,112 - 94,489,800 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,873,282 - 95,889,973 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	93,047,983 - 93,064,680 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	98,513,600 - 98,539,347 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	98,513,570 - 98,530,724 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	103,521,460 - 103,547,174 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	95,934,674 - 95,951,836 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	96,123,177 - 96,145,989 (-)	NCBI
Celera	13	91,515,731 - 91,532,398 (-)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

PSEN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	22,644,288 - 22,669,733 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	22,592,732 - 22,618,185 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	202,328,987 - 202,354,440 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	207,320,937 - 207,346,295 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	207,320,937 - 207,346,295 (+)	Ensembl	panpan1.1		panPan2

PSEN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	38,147,157 - 38,163,023 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	38,147,173 - 38,166,722 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	37,629,753 - 37,654,335 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	37,981,322 - 38,006,377 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	37,980,700 - 38,006,369 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	37,820,678 - 37,845,261 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	37,827,826 - 37,852,402 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	38,098,241 - 38,122,853 (-)	NCBI		UU_Cfam_GSD_1.0

Psen2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	51,135,578 - 51,163,137 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	3,584,188 - 3,614,074 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	3,584,194 - 3,611,719 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSEN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	14,532,767 - 14,577,251 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	14,532,556 - 14,561,862 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	16,862,708 - 16,891,775 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	10	p16-p11	NCBI

PSEN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	2,862,354 - 2,888,735 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	2,862,251 - 2,877,386 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	2,849,316 - 2,875,698 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psen2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	17,183,447 - 17,224,188 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624771	17,183,538 - 17,205,460 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005374755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01005739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01041147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01074852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000020319 ⟹ ENSCLAP00000020124

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955406	5,727,367 - 5,752,234 (+)	Ensembl

RefSeq Acc Id:

XM_005374755 ⟹ XP_005374812

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955406	5,727,367 - 5,748,798 (+)	NCBI

Sequence:

show sequence

GGAGCGGCAAGGCGTCGCCGCGGAGCAGGCGGGCGGGCGGGGCGGCGGCGGGGGGCGGGGCGCG
GGCGGGCCGGCAAGGCGGCGCACGCGCTCTCGGGGCCGAGCGGAGCCTCGCGGGCGCCCGCCGC
CTGCGCCGAGCCGAGGGGAGCCGGGCCTGCTGCCGGCCGCGCTCGCCGCCCAGGTTGCCTGTTT
TATCTGGGCTTTGCAGCCGTGCGGAGACGCCCCGACCGCAGCGTTGGACGCTGAAGGAGCCCGA
AAACACAAGCGGGTCCCCCTTCTGCATTTGACTGATGAAGAAACTGAGCCCACAGAGCTAAAGT
GACACAGCCCAAGGTCGCCCAGGTACACCCCCTTCCTGAGAGGGCCATGCTGACGTTCATGGCC
TCTGACAGCGAGGAGGAAGCGTGCGACGAGCGGACGTCCCTGATGTCGGCCGAGAGCCCCTCGC
CGCGCTCCTGCCAGGAGGCCCGGCAGGGCGAGGAGGACGGGGACAGCGCTTCGCAGTGGAGGAG
CCAGGAGAGCGAGGAGGACTTCGAGGATGACCCTGACCGCTACATCTGCAGTGGGGTCCCTGGG
CGGCCACCAGGCCTGGAGGAGGAGCTGACCCTGAAGTACGGGGCGAAGCACGTGATCATGCTGT
TCGTGCCCGTCACGCTGTGCATGATTGTGGTGGTGGCCACCATCAAGTCCGTGCGCTTCTACAC
CGAGAAGAATGGTCAGCTCATCTACACGCCATTCACCGAGGACACGCCCTCCGTGGGCCAGCGC
CTCCTCAACTCCGTGCTGAACACCCTCATCATGATCAGCGTCATCGTGGTCATGACCATCTTCC
TGGTGGTGCTGTACAAGTACCGCTGCTACAAGTTCATCCACGGCTGGCTGATCGTGTCCTCCCT
GATGCTGCTGTTCCTGTTCACCTACGTCTACCTCGGGGAAGTGCTCAAGACCTACAACGTGGCC
ATGGACTACCCCACGCTCTTCCTGACCGTGTGGAACTTCGGGGCGGTGGGCATGGTGTGCATCC
ACTGGAAGGGCCCCCTGGTGCTGCAGCAGGCCTACCTCATCATGATCAGCGCCCTCATGGCCCT
GGTGTTCATCAAGTACCTCCCAGAGTGGTCCGCGTGGGTCATCCTGGGCGCCATCTCCGTGTAT
GATCTCGTGGCGGTGCTGTGCCCCAAAGGGCCTCTGAGGATGCTGGTGGAGACCGCCCAGGAGA
GGAACGAGCCCATCTTTCCTGCCCTGATATACTCCTCTGCCATGGTGTGGACAGTGGGCATGGC
AAAGCTGGACCCGTCCTCACAGGGCGCCCTGCAGCTCCCCTATGACCCGGAGATGGAAGAAGAC
TCCTATGACAGTTTTGGGGAGCCCTCGTACCCTGATGTCTTCGAGCCCCCCATGCCTGGCTACC
CCGGGGAAGAGCTGGAGGAAGAGGAGGAAAGGGGCGTGAAGCTCGGCCTGGGCGACTTCATCTT
TTACAGCGTGCTGGTGGGCAAGGCGGCGGCCACGGGCAGCGGGGACTGGAACACCACGCTGGCC
TGCTTCGTGGCCATCCTCATCGGCCTGTGTCTGACCCTCCTGCTGCTCGCCGTGTTCAAGAAAG
CGCTGCCTGCCCTGCCCATCTCTATCACCTTCGGGCTCATCTTCTACTTCTCCACCGACAACCT
GGTGCGGCCCTTCATGGATACCCTGGCCTCCCACCAGCTCTACATCTGACCGGCCGCTTCCCGG
GACGCAGCTGTGTAGTTTTACACTCTAGTGCCATATATTTTTAAGACTTTCCTTTCCTTACAAA
AATAAACAGATACTGTGTTTACTTCGTGACGAGGAAGCAGGAGCCGCTTTTTGGTGCTAGCTGT
TTTGTCACCAGACTCTGCCTCACCCGCGTGTGCACCTTGCGTCACCGACAGGATACGGCAGGCT
CATCCGAGTGAACGGGAGAGGTCACGTGGTGTGCGGGCCTGGAGGAGAATGCCCGTTCCCCTCC
TGTCCCGGACCGGAAACCTCGAGGGCACAGGAGGGAGGTGGTCCACAGTGGCGCTGGGGAGAAG
CCCCAGGCACCGCTGGCTCTGGCCGAGAAGAAATCCAGGTGCCTGTCAGGAGTGTGTTCAGTGC
GTTCTCTGTGGTGTCCTTGTTGTTTTATTCCCTTTAGACACAGTCCTGTTTTTCCTGCTGGGGC
GTGGCTTAATGTGAACATCAGTAAATCGATGCCTCCTGTCTCGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005374812	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000020124
	ENSCLAP00000020124.1

RefSeq Acc Id:

XP_005374812 ⟸ XM_005374755

- UniProtKB:

A0A8C2VVG0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLTFMASDSEEEACDERTSLMSAESPSPRSCQEARQGEEDGDSASQWRSQESEEDFEDDPDRYI
CSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDT
PSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIVSSLMLLFLFTYVYLGEVL
KTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVIL
GAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYD
PEMEEDSYDSFGEPSYPDVFEPPMPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGD
WNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI

hide sequence

RefSeq Acc Id:

ENSCLAP00000020124 ⟸ ENSCLAT00000020319

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013788	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000020319	ENTREZGENE
	ENSCLAT00000020319.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.472.100	UniProtKB/TrEMBL
InterPro	Pept_A22A_PS2	UniProtKB/TrEMBL
	Peptidase_A22A	UniProtKB/TrEMBL
	Preselin/SPP	UniProtKB/TrEMBL
	Presenilin_C	UniProtKB/TrEMBL
NCBI Gene	LOC102025650	ENTREZGENE
PANTHER	PRESENILIN-2	UniProtKB/TrEMBL
	PTHR10202	UniProtKB/TrEMBL
Pfam	Presenilin	UniProtKB/TrEMBL
PRINTS	PRESENILIN	UniProtKB/TrEMBL
	PRESENILIN2	UniProtKB/TrEMBL
SMART	PSN	UniProtKB/TrEMBL
UniProt	A0A8C2VVG0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Psen2	presenilin 2	LOC102025650	presenilin-2-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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