Dek (DEK proto-oncogene) - Rat Genome Database

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Gene: Dek (DEK proto-oncogene) Chinchilla lanigera
Analyze
Symbol: Dek
Name: DEK proto-oncogene
RGD ID: 9025654
Description: ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase III (ortholog); regulation of double-strand break repair (ortholog); regulation of double-strand break repair via nonhomologous end joining (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Breast Neoplasms (ortholog); genetic disease (ortholog); FOUND IN B-WICH complex (ortholog); contractile fiber (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540828,470,207 - 28,472,083 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dek
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540828,470,207 - 28,472,083 (-)NCBIChiLan1.0ChiLan1.0
DEK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38618,223,860 - 18,264,530 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl618,223,860 - 18,264,548 (-)EnsemblGRCh38hg38GRCh38
GRCh37618,224,091 - 18,264,761 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36618,332,379 - 18,372,778 (-)NCBINCBI36Build 36hg18NCBI36
Build 34618,332,391 - 18,372,750NCBI
Celera619,462,368 - 19,502,747 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef618,168,737 - 18,209,264 (-)NCBIHuRef
CHM1_1618,226,996 - 18,267,392 (-)NCBICHM1_1
T2T-CHM13v2.0618,096,002 - 18,136,672 (-)NCBIT2T-CHM13v2.0
Dek
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391347,238,243 - 47,261,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1347,238,251 - 47,259,677 (-)EnsemblGRCm39 Ensembl
GRCm381347,084,767 - 47,107,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1347,084,775 - 47,106,201 (-)EnsemblGRCm38mm10GRCm38
MGSCv371347,180,136 - 47,201,589 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361347,095,757 - 47,117,082 (-)NCBIMGSCv36mm8
Celera1348,169,343 - 48,190,333 (-)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1324.5NCBI
Dek
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81717,786,989 - 17,809,096 (+)NCBIGRCr8
mRatBN7.21717,580,804 - 17,602,825 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1717,580,843 - 17,602,808 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1717,467,321 - 17,488,966 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01719,071,178 - 19,092,823 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01717,394,438 - 17,416,083 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01717,965,872 - 17,987,836 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1717,965,881 - 17,987,834 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01719,948,512 - 19,970,498 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41723,633,551 - 23,655,507 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11723,633,599 - 23,655,553 (+)NCBI
Celera1717,292,456 - 17,314,107 (+)NCBICelera
Cytogenetic Map17p14NCBI
DEK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2532,883,587 - 32,923,584 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1628,868,850 - 28,909,152 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0618,071,928 - 18,112,245 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1618,425,882 - 18,465,828 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl618,427,844 - 18,465,606 (-)Ensemblpanpan1.1panPan2
LOC100688177
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1310,279,204 - 10,280,935 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha311,622,628 - 11,624,150 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0310,169,743 - 10,171,465 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1310,110,427 - 10,111,962 (-)NCBIUMICH_Zoey_3.1
Dek
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049467,737,766 - 7,766,430 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365523,966,198 - 3,993,113 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365523,964,515 - 3,997,318 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl713,872,775 - 13,935,173 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1713,901,562 - 13,935,477 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2714,643,279 - 14,676,979 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DEK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11753,879,902 - 53,919,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604418,447,488 - 18,487,777 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dek
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247568,421,782 - 8,447,452 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247568,421,492 - 8,447,452 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013509494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01008713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_013509494   ⟹   XP_013364948
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540828,470,207 - 28,472,083 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013364948 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021877.1
RefSeq Acc Id: XP_013364948   ⟸   XM_013509494
- Sequence:
Protein Domains
DEK-C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014990 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022081.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro DEK UniProtKB/TrEMBL
  DEK_C UniProtKB/TrEMBL
NCBI Gene LOC102008065 ENTREZGENE
PANTHER PROTEIN DEK UniProtKB/TrEMBL
  PTHR13468 UniProtKB/TrEMBL
Pfam DEK_C UniProtKB/TrEMBL
PROSITE DEK_C UniProtKB/TrEMBL
Superfamily-SCOP DEK C-terminal domain UniProtKB/TrEMBL
UniProt A0A8C2W228_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Dek  DEK proto-oncogene  LOC102008065  protein DEK-like  Symbol and/or name change 5135510 APPROVED