Ldhb (lactate dehydrogenase B) - Rat Genome Database

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Gene: Ldhb (lactate dehydrogenase B) Chinchilla lanigera
Analyze
Symbol: Ldhb
Name: lactate dehydrogenase B
RGD ID: 8995948
Description: ENCODES a protein that exhibits identical protein binding (ortholog); kinase binding (ortholog); L-lactate dehydrogenase activity (ortholog); INVOLVED IN lactate metabolic process (ortholog); NAD metabolic process (ortholog); pyruvate metabolic process (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Breast Neoplasms (ortholog); dilated cardiomyopathy 1O (ortholog); FOUND IN cytosol (ortholog); membrane raft (ortholog); mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: L-lactate dehydrogenase B chain
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,261,118 - 17,283,593 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541317,264,337 - 17,283,530 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ldhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,261,118 - 17,283,593 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541317,264,337 - 17,283,530 (-)NCBIChiLan1.0ChiLan1.0
LDHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,635,342 - 21,657,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,635,342 - 21,757,857 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,788,276 - 21,810,776 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,679,543 - 21,702,043 (-)NCBINCBI36Build 36hg18NCBI36
Build 341221,679,544 - 21,702,042NCBI
Celera1226,943,264 - 26,965,789 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,561,869 - 21,584,405 (-)NCBIHuRef
CHM1_11221,753,523 - 21,776,056 (-)NCBICHM1_1
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBIT2T-CHM13v2.0
Ldhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,435,975 - 142,453,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,435,975 - 142,453,683 (-)EnsemblGRCm39 Ensembl
GRCm386142,490,249 - 142,507,957 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,490,249 - 142,507,957 (-)EnsemblGRCm38mm10GRCm38
MGSCv376142,438,769 - 142,456,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366142,447,471 - 142,465,165 (-)NCBIMGSCv36mm8
Celera6145,551,908 - 145,569,602 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map674.17NCBI
Ldhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,159,389 - 177,177,408 (-)NCBIGRCr8
mRatBN7.24175,428,382 - 175,446,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,428,385 - 175,446,403 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4181,723,217 - 181,741,234 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,507,488 - 177,525,505 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,128,058 - 176,146,075 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,701,980 - 176,719,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,701,983 - 176,720,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,918,027 - 240,936,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44180,061,567 - 180,079,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14180,306,690 - 180,322,406 (-)NCBI
Celera4163,963,498 - 163,981,517 (-)NCBICelera
Cytogenetic Map4q44NCBI
LDHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21075,145,106 - 75,167,533 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11275,141,504 - 75,163,931 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01264,640,994 - 64,663,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11267,245,012 - 67,267,487 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1267,245,130 - 67,267,487 (+)Ensemblpanpan1.1panPan2
LDHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12725,470,666 - 25,493,114 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2725,470,665 - 25,492,920 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2720,864,321 - 20,886,793 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02725,693,648 - 25,716,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,693,609 - 25,716,160 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12725,492,290 - 25,514,750 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02725,515,724 - 25,538,195 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02721,035,083 - 21,057,566 (-)NCBIUU_Cfam_GSD_1.0
Ldhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,301,989 - 87,321,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365485,227,666 - 5,244,525 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365485,224,905 - 5,244,708 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1551,810,932 - 51,831,218 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2555,086,895 - 55,106,892 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LDHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,489,815 - 21,511,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,488,814 - 21,511,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606913,631,514 - 13,654,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ldhb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475217,049,296 - 17,069,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475217,046,640 - 17,065,910 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000023922   ⟹   ENSCLAP00000023696
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541317,261,118 - 17,283,593 (-)Ensembl
RefSeq Acc Id: XM_005379063   ⟹   XP_005379120
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541317,264,337 - 17,283,530 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005379120 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000023696
  ENSCLAP00000023696.1
RefSeq Acc Id: XP_005379120   ⟸   XM_005379063
- UniProtKB: A0A8C2YU82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000023696   ⟸   ENSCLAT00000023922

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016258 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023922 ENTREZGENE
  ENSCLAT00000023922.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.110.10 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro L-lactate/malate_DH UniProtKB/TrEMBL
  L-lactate_DH UniProtKB/TrEMBL
  L-lactate_DH_AS UniProtKB/TrEMBL
  Lactate/malate_DH_C UniProtKB/TrEMBL
  Lactate/malate_DH_N UniProtKB/TrEMBL
  Lactate_DH/Glyco_Ohase_4_C UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Ldhb ENTREZGENE
PANTHER L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) UniProtKB/TrEMBL
  L-LACTATE DEHYDROGENASE B CHAIN UniProtKB/TrEMBL
Pfam Ldh_1_C UniProtKB/TrEMBL
  Ldh_1_N UniProtKB/TrEMBL
PIRSF Lac_mal_DH UniProtKB/TrEMBL
PRINTS LLDHDRGNASE UniProtKB/TrEMBL
PROSITE L_LDH UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
  SSF56327 UniProtKB/TrEMBL
UniProt A0A8C2YU82 ENTREZGENE, UniProtKB/TrEMBL