Grm2 (glutamate metabotropic receptor 2) - Rat Genome Database

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Gene: Grm2 (glutamate metabotropic receptor 2) Chinchilla lanigera
Analyze
Symbol: Grm2
Name: glutamate metabotropic receptor 2
RGD ID: 8984079
Description: ENCODES a protein that exhibits calcium channel regulator activity (ortholog); group II metabotropic glutamate receptor activity (ortholog); scaffold protein binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); gene expression (ortholog); glutamate receptor signaling pathway (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); Binge Drinking (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN astrocyte projection (ortholog); axon (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate receptor, metabotropic 2; metabotropic glutamate receptor 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,309,028 - 3,320,966 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,309,034 - 3,320,954 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Grm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,309,028 - 3,320,966 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,309,034 - 3,320,954 (+)NCBIChiLan1.0ChiLan1.0
GRM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,707,068 - 51,718,613 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,707,068 - 51,718,613 (+)EnsemblGRCh38hg38GRCh38
GRCh37351,741,084 - 51,752,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,718,004 - 51,727,669 (+)NCBINCBI36Build 36hg18NCBI36
Build 34351,718,037 - 51,727,168NCBI
Celera351,718,848 - 51,731,506 (+)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef351,802,839 - 51,816,142 (+)NCBIHuRef
CHM1_1351,693,893 - 51,705,447 (+)NCBICHM1_1
T2T-CHM13v2.0351,738,578 - 51,751,605 (+)NCBIT2T-CHM13v2.0
Grm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,521,733 - 106,533,308 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,520,294 - 106,533,281 (-)EnsemblGRCm39 Ensembl
GRCm389106,644,534 - 106,656,109 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,643,095 - 106,656,082 (-)EnsemblGRCm38mm10GRCm38
MGSCv379106,546,865 - 106,558,440 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,546,755 - 106,558,434 (-)NCBIMGSCv36mm8
Celera9106,265,562 - 106,277,130 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.98NCBI
Grm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88116,158,810 - 116,171,857 (-)NCBIGRCr8
mRatBN7.28107,280,099 - 107,293,159 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,280,099 - 107,293,146 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,903,031 - 112,916,129 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08111,102,213 - 111,115,309 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,944,991 - 108,958,085 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,344,999 - 115,358,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,344,999 - 115,358,046 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,705,123 - 114,718,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,837,086 - 111,850,133 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,857,819 - 111,869,581 (-)NCBI
Celera8106,592,051 - 106,605,096 (-)NCBICelera
Cytogenetic Map8q32NCBI
GRM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,694,559 - 51,707,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,699,333 - 51,712,208 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,639,792 - 51,652,779 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1352,873,144 - 52,884,401 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl352,873,144 - 52,884,395 (+)Ensemblpanpan1.1panPan2
GRM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,915,178 - 37,926,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,915,665 - 37,924,296 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,895,193 - 37,906,256 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,264,331 - 38,275,394 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2038,264,304 - 38,275,372 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,627,888 - 37,638,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02038,036,604 - 38,047,669 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,321,755 - 38,332,818 (-)NCBIUU_Cfam_GSD_1.0
Grm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,281,725 - 66,293,182 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,042,248 - 3,053,673 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,042,220 - 3,053,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1333,926,804 - 33,938,269 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11333,924,303 - 33,938,279 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,130,553 - 37,141,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,044,974 - 13,056,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,046,641 - 13,056,453 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,898,374 - 153,910,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,419,896 - 5,431,361 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,419,892 - 5,431,268 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000013739   ⟹   ENSCLAP00000013584
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555323,309,028 - 3,320,966 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000013740   ⟹   ENSCLAP00000013585
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555323,310,319 - 3,320,966 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000013741   ⟹   ENSCLAP00000013586
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555323,310,828 - 3,318,632 (+)Ensembl
RefSeq Acc Id: XM_005410320   ⟹   XP_005410377
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555323,310,319 - 3,320,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005410321   ⟹   XP_005410378
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555323,309,060 - 3,320,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013507564   ⟹   XP_013363018
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555323,309,034 - 3,320,954 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005410377 (Get FASTA)   NCBI Sequence Viewer  
  XP_005410378 (Get FASTA)   NCBI Sequence Viewer  
  XP_013363018 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013584
  ENSCLAP00000013584.1
  ENSCLAP00000013585
  ENSCLAP00000013585.1
  ENSCLAP00000013586.1
Reference Protein Sequences
RefSeq Acc Id: XP_005410378   ⟸   XM_005410321
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YPF1 (UniProtKB/TrEMBL),   A0A8C2VCJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005410377   ⟸   XM_005410320
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VCJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363018   ⟸   XM_013507564
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YPF1 (UniProtKB/TrEMBL),   A0A8C2VCJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000013584   ⟸   ENSCLAT00000013739
RefSeq Acc Id: ENSCLAP00000013586   ⟸   ENSCLAT00000013741
RefSeq Acc Id: ENSCLAP00000013585   ⟸   ENSCLAT00000013740
Protein Domains
G-protein coupled receptors family 3 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009387 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013739 ENTREZGENE
  ENSCLAT00000013739.1 UniProtKB/TrEMBL
  ENSCLAT00000013740 ENTREZGENE
  ENSCLAT00000013740.1 UniProtKB/TrEMBL
  ENSCLAT00000013741.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_CS UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt_2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Grm2 ENTREZGENE
PANTHER METABOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
  METABOTROPIC GLUTAMATE RECEPTOR 2 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PRINTS GPCRMGR UniProtKB/TrEMBL
  MTABOTROPC2R UniProtKB/TrEMBL
  MTABOTROPICR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8C2VCJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YPF0_CHILA UniProtKB/TrEMBL
  A0A8C2YPF1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Grm2  glutamate metabotropic receptor 2    glutamate receptor, metabotropic 2  Symbol and/or name change 5135510 APPROVED