Adcy1 (adenylate cyclase 1) - Rat Genome Database

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Gene: Adcy1 (adenylate cyclase 1) Chinchilla lanigera
Analyze
Symbol: Adcy1
Name: adenylate cyclase 1
RGD ID: 8950801
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); calcium- and calmodulin-responsive adenylate cyclase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cAMP biosynthetic process (ortholog); circadian rhythm (ortholog); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; protein kinase A (PKA) signaling pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 44 (ortholog); genetic disease (ortholog); Hyperkinesis (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate cyclase 1 (brain); adenylate cyclase type 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,841,637 - 6,930,990 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,833,992 - 6,930,990 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adcy1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,841,637 - 6,930,990 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,833,992 - 6,930,990 (-)NCBIChiLan1.0ChiLan1.0
ADCY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,574,140 - 45,723,116 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,574,140 - 45,723,116 (+)EnsemblGRCh38hg38GRCh38
GRCh37745,613,739 - 45,762,715 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,580,646 - 45,729,237 (+)NCBINCBI36Build 36hg18NCBI36
Build 34745,387,360 - 45,535,952NCBI
Celera745,713,145 - 45,861,628 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef745,497,881 - 45,646,668 (+)NCBIHuRef
CHM1_1745,617,991 - 45,766,937 (+)NCBICHM1_1
T2T-CHM13v2.0745,734,849 - 45,884,850 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,653,346 - 45,802,046 (+)NCBI
Adcy1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,013,433 - 7,128,506 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl117,013,489 - 7,128,506 (+)EnsemblGRCm39 Ensembl
GRCm38117,063,433 - 7,178,506 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,063,489 - 7,178,506 (+)EnsemblGRCm38mm10GRCm38
MGSCv37116,963,492 - 7,078,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,963,492 - 7,078,509 (+)NCBIMGSCv36mm8
Celera117,538,560 - 7,653,962 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.72NCBI
Adcy1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,125,119 - 86,234,459 (+)NCBIGRCr8
mRatBN7.21481,911,240 - 82,020,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,911,099 - 82,028,969 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1486,312,501 - 86,421,804 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,552,335 - 87,661,649 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01484,001,921 - 84,110,208 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01487,311,970 - 87,429,880 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,312,203 - 87,421,659 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,947,153 - 81,055,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,812,256 - 87,923,402 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11487,831,237 - 87,942,547 (+)NCBI
Celera1480,985,818 - 81,095,021 (+)NCBICelera
Cytogenetic Map14q21NCBI
ADCY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2650,488,461 - 50,636,235 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,813,198 - 98,963,382 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0746,289,042 - 46,436,839 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1746,354,645 - 46,501,637 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl746,354,640 - 46,492,549 (+)Ensemblpanpan1.1panPan2
ADCY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,064,644 - 1,166,864 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,037,162 - 1,167,094 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha16484,554 - 595,249 (-)NCBIDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha161,840,487 - 1,857,161 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0161,051,164 - 1,153,484 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl161,023,782 - 1,153,699 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1161,041,775 - 1,139,427 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016977,374 - 1,056,190 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01696,213 - 197,299 (+)NCBIUU_Cfam_GSD_1.0
Adcy1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,098,778 - 101,252,942 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647820,310,503 - 20,456,141 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647820,310,509 - 20,477,506 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,051,364 - 50,143,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,043,572 - 50,143,549 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,887,477 - 54,978,872 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,976,687 - 13,117,876 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2112,979,033 - 13,117,730 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660629,421,819 - 9,563,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247406,922,879 - 7,003,658 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247406,915,445 - 7,003,299 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007904   ⟹   ENSCLAP00000007784
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554566,841,637 - 6,930,990 (-)Ensembl
RefSeq Acc Id: XM_005396644   ⟹   XP_005396701
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554566,833,992 - 6,930,990 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396701 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007784
  ENSCLAP00000007784.1
Reference Protein Sequences
RefSeq Acc Id: XP_005396701   ⟸   XM_005396644
- UniProtKB: A0A8C2UYU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007784   ⟸   ENSCLAT00000007904
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005463 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007904 ENTREZGENE
  ENSCLAT00000007904.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1230 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  AC_N UniProtKB/TrEMBL
  Adcy UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Adcy1 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
  ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
Pfam AC_N UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/TrEMBL
PIRSF Ade_cyc UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF55073 UniProtKB/TrEMBL
UniProt A0A8C2UYU9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Adcy1  adenylate cyclase 1    adenylate cyclase 1 (brain)  Symbol and/or name change 5135510 APPROVED