Agrn (agrin) - Rat Genome Database

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Gene: Agrn (agrin) Chinchilla lanigera
Analyze
Symbol: Agrn
Name: agrin
RGD ID: 8944397
Description: ENCODES a protein that exhibits acetylcholine receptor regulator activity (ortholog); ATPase inhibitor activity (ortholog); BMP binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); circadian rhythm (ortholog); enzyme-linked receptor protein signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH acute myeloid leukemia (ortholog); chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN basement membrane; axonal growth cone (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,675,214 - 9,704,991 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,674,103 - 9,704,994 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Proteoglycan arrays in the cochlear basement membrane. Tsuprun V and Santi P, Hear Res. 2001 Jul;157(1-2):65-76.
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Agrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,675,214 - 9,704,991 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,674,103 - 9,704,994 (-)NCBIChiLan1.0ChiLan1.0
AGRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,020,120 - 1,056,116 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,020,120 - 1,056,118 (+)EnsemblGRCh38hg38GRCh38
GRCh371955,500 - 991,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,366 - 981,355 (+)NCBINCBI36Build 36hg18NCBI36
Celera11,597,136 - 1,631,462 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1226,888 - 263,237 (+)NCBIHuRef
CHM1_11942,522 - 978,540 (+)NCBICHM1_1
T2T-CHM13v2.01450,247 - 486,181 (+)NCBIT2T-CHM13v2.0
Agrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,249,747 - 156,281,997 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,249,747 - 156,281,945 (-)EnsemblGRCm39 Ensembl
GRCm384156,165,290 - 156,197,533 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,165,290 - 156,197,488 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,539,399 - 155,559,244 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364155,009,090 - 155,028,935 (-)NCBIMGSCv36mm8
Celera4158,419,989 - 158,441,614 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map488.55NCBI
Agrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85172,031,528 - 172,064,429 (-)NCBIGRCr8
mRatBN7.25166,749,306 - 166,782,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,749,310 - 166,786,003 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,451,492 - 169,472,811 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,272,883 - 171,294,202 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,235,444 - 171,256,763 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,589,910 - 173,622,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,589,819 - 173,622,645 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05177,063,797 - 177,096,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,999,420 - 173,020,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15173,009,918 - 173,031,259 (-)NCBI
Celera5164,949,181 - 164,970,209 (-)NCBICelera
Cytogenetic Map5q36NCBI
AGRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,197,744 - 227,232,423 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,893,486 - 225,928,339 (-)NCBINHGRI_mPanPan1
PanPan1.11953,977 - 967,946 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1936,000 - 966,808 (+)Ensemblpanpan1.1panPan2
AGRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,239,621 - 56,273,679 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,239,701 - 56,272,745 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,317,660 - 56,351,511 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,443,168 - 56,477,026 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,443,113 - 56,476,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,434,207 - 56,468,062 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,326,114 - 56,359,961 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,716,182 - 56,750,025 (+)NCBIUU_Cfam_GSD_1.0
Agrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,426,638 - 27,455,302 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367372,011,724 - 2,039,796 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367372,010,647 - 2,041,401 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,365,983 - 63,398,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,366,017 - 63,398,311 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2657,851,241 - 57,880,816 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,383,226 - 130,416,926 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,383,220 - 130,416,933 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,009,405 - 35,044,463 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,476,562 - 8,508,786 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248188,475,453 - 8,508,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000015485   ⟹   ENSCLAP00000015325
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554869,675,214 - 9,704,991 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015486   ⟹   ENSCLAP00000015326
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554869,675,214 - 9,693,627 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015487   ⟹   ENSCLAP00000015327
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554869,677,898 - 9,693,627 (-)Ensembl
RefSeq Acc Id: XM_013504201   ⟹   XP_013359655
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554869,674,103 - 9,704,994 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013359655 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015325
  ENSCLAP00000015325.1
  ENSCLAP00000015326.1
  ENSCLAP00000015327.1
Reference Protein Sequences
RefSeq Acc Id: XP_013359655   ⟸   XM_013504201
- UniProtKB: A0A8C2YQ92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015325   ⟸   ENSCLAT00000015485
RefSeq Acc Id: ENSCLAP00000015327   ⟸   ENSCLAT00000015487
RefSeq Acc Id: ENSCLAP00000015326   ⟸   ENSCLAT00000015486
Protein Domains
EGF-like   Kazal-like   Laminin EGF-like   Laminin G   NtA   SEA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010553 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015485 ENTREZGENE
  ENSCLAT00000015485.1 UniProtKB/TrEMBL
  ENSCLAT00000015486.1 UniProtKB/TrEMBL
  ENSCLAT00000015487.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.120 UniProtKB/TrEMBL
  2.60.120.200 UniProtKB/TrEMBL
  3.30.60.30 UniProtKB/TrEMBL
  3.30.70.960 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  FacI_MAC UniProtKB/TrEMBL
  Fol_N UniProtKB/TrEMBL
  Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  LE_dom UniProtKB/TrEMBL
  NtA_dom UniProtKB/TrEMBL
  SEA_dom UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
NCBI Gene Agrn ENTREZGENE
PANTHER AGRIN UniProtKB/TrEMBL
  AGRIN UniProtKB/TrEMBL
  FOLLISTATIN-RELATED UniProtKB/TrEMBL
  PIKACHURIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  Kazal_1 UniProtKB/TrEMBL
  Kazal_2 UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  NtA UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  NTA UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  FIMAC UniProtKB/TrEMBL
  FOLN UniProtKB/TrEMBL
  KAZAL UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF100895 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF50242 UniProtKB/TrEMBL
  SSF82671 UniProtKB/TrEMBL
UniProt A0A8C2VGY8_CHILA UniProtKB/TrEMBL
  A0A8C2YQ89_CHILA UniProtKB/TrEMBL
  A0A8C2YQ92 ENTREZGENE, UniProtKB/TrEMBL