Fgf1 (fibroblast growth factor 1) - Rat Genome Database

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Gene: Fgf1 (fibroblast growth factor 1) Chinchilla lanigera
Analyze
Symbol: Fgf1
Name: fibroblast growth factor 1
RGD ID: 8930334
Description: ENCODES a protein that exhibits fibroblast growth factor receptor binding (ortholog); growth factor activity (ortholog); heparin binding (ortholog); INVOLVED IN branch elongation involved in ureteric bud branching (ortholog); cellular response to heat (ortholog); epithelial cell proliferation (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); cleft lip (ortholog); FOUND IN cytosol (ortholog); extracellular matrix (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibroblast growth factor 1 (acidic)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541511,151,266 - 11,247,344 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541511,151,330 - 11,245,554 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fgf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541511,151,266 - 11,247,344 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541511,151,330 - 11,245,554 (+)NCBIChiLan1.0ChiLan1.0
FGF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385142,592,178 - 142,698,070 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5142,592,178 - 142,698,070 (-)EnsemblGRCh38hg38GRCh38
GRCh375141,971,743 - 142,077,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365141,953,306 - 142,045,812 (-)NCBINCBI36Build 36hg18NCBI36
Build 345141,953,306 - 142,045,812NCBI
Celera5138,053,068 - 138,158,948 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5137,119,474 - 137,224,982 (-)NCBIHuRef
CHM1_15141,405,414 - 141,511,305 (-)NCBICHM1_1
T2T-CHM13v2.05143,123,428 - 143,229,306 (-)NCBIT2T-CHM13v2.0
Fgf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391838,971,725 - 39,062,532 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1838,971,726 - 39,062,525 (-)EnsemblGRCm39 Ensembl
GRCm381838,838,672 - 38,929,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1838,838,673 - 38,929,472 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,998,327 - 39,078,353 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361838,965,154 - 39,044,673 (-)NCBIMGSCv36mm8
Celera1840,186,840 - 40,265,902 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1820.74NCBI
Fgf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81830,937,670 - 31,023,786 (-)NCBIGRCr8
mRatBN7.21830,686,555 - 30,772,667 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1830,686,581 - 30,772,357 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1830,793,473 - 30,814,440 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01831,554,441 - 31,575,416 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01830,888,710 - 30,909,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01832,273,830 - 32,359,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1832,273,770 - 32,359,824 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01831,951,411 - 32,037,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41831,785,480 - 31,806,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11831,815,644 - 31,836,615 (-)NCBI
Celera1830,325,334 - 30,346,306 (-)NCBICelera
RH 3.4 Map18442.3RGD
Cytogenetic Map18p11NCBI
FGF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24137,837,020 - 137,929,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15135,976,573 - 136,069,372 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05137,949,100 - 138,054,553 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15144,056,387 - 144,161,906 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5144,056,387 - 144,078,001 (-)Ensemblpanpan1.1panPan2
FGF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1237,467,431 - 37,554,770 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl237,470,985 - 37,554,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha234,520,400 - 34,607,331 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0237,924,029 - 38,010,951 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl237,924,031 - 38,011,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1235,002,929 - 35,089,106 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0235,815,172 - 35,902,044 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,617,132 - 36,703,569 (-)NCBIUU_Cfam_GSD_1.0
Fgf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,016,744 - 150,111,186 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650411,590,637 - 11,685,194 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650411,590,687 - 11,684,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2144,133,392 - 144,241,323 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12144,133,846 - 144,241,345 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22150,317,372 - 150,435,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12345,220,827 - 45,328,387 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2345,220,800 - 45,328,328 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603432,516,959 - 32,624,610 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247741,779,170 - 1,867,300 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247741,779,168 - 1,867,321 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014528   ⟹   ENSCLAP00000014370
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541511,151,266 - 11,247,344 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014529   ⟹   ENSCLAP00000014371
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541511,151,616 - 11,242,564 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014530   ⟹   ENSCLAP00000014372
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541511,198,831 - 11,247,344 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014531   ⟹   ENSCLAP00000014373
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541511,226,358 - 11,242,330 (+)Ensembl
RefSeq Acc Id: XM_005380699   ⟹   XP_005380756
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,151,330 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380701   ⟹   XP_005380758
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,151,330 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380702   ⟹   XP_005380759
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,219,324 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380703   ⟹   XP_005380760
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,213,603 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380707   ⟹   XP_005380764
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,151,330 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512345   ⟹   XP_013367799
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,151,330 - 11,192,446 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512346   ⟹   XP_013367800
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,186,603 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512347   ⟹   XP_013367801
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,160,129 - 11,245,554 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512348   ⟹   XP_013367802
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541511,198,831 - 11,245,554 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005380756   ⟸   XM_005380699
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005380764   ⟸   XM_005380707
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005380758   ⟸   XM_005380701
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005380760   ⟸   XM_005380703
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005380759   ⟸   XM_005380702
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367799   ⟸   XM_013512345
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013367801   ⟸   XM_013512347
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367800   ⟸   XM_013512346
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367802   ⟸   XM_013512348
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000014370   ⟸   ENSCLAT00000014528
RefSeq Acc Id: ENSCLAP00000014371   ⟸   ENSCLAT00000014529
RefSeq Acc Id: ENSCLAP00000014372   ⟸   ENSCLAT00000014530
RefSeq Acc Id: ENSCLAP00000014373   ⟸   ENSCLAT00000014531


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009907 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014528.1 UniProtKB/TrEMBL
  ENSCLAT00000014529 ENTREZGENE
  ENSCLAT00000014529.1 UniProtKB/TrEMBL
  ENSCLAT00000014530 ENTREZGENE
  ENSCLAT00000014530.1 UniProtKB/TrEMBL
  ENSCLAT00000014531.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
  6.20.90.30 UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
NCBI Gene Fgf1 ENTREZGENE
PANTHER PTHR11486 UniProtKB/TrEMBL
  PTHR11486:SF86 UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PRINTS HBGFFGF UniProtKB/TrEMBL
  IL1HBGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/TrEMBL
UniProt A0A8C2VIC0_CHILA UniProtKB/TrEMBL
  A0A8C2VJW7_CHILA UniProtKB/TrEMBL
  A0A8C2VKZ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Fgf1  fibroblast growth factor 1    fibroblast growth factor 1 (acidic)  Symbol and/or name change 5135510 APPROVED