Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1) - Rat Genome Database

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Gene: Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1) Chinchilla lanigera
Analyze
Symbol: Gucy1a1
Name: guanylate cyclase 1 soluble subunit alpha 1
RGD ID: 8911366
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); cytidylate cyclase activity (ortholog); guanylate cyclase activity (ortholog); INVOLVED IN cGMP biosynthetic process (ortholog); nitric oxide mediated signal transduction (ortholog); nitric oxide-cGMP-mediated signaling (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Colonic Neoplasms (ortholog); coronary artery disease (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); guanylate cyclase complex, soluble (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanylate cyclase 1 soluble subunit alpha; guanylate cyclase 1, soluble, alpha 3; guanylate cyclase soluble subunit alpha-3; Gucy1a3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,424,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,367,318 - 11,422,199 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gucy1a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,424,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,367,318 - 11,422,199 (-)NCBIChiLan1.0ChiLan1.0
GUCY1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,666,848 - 155,737,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4155,666,726 - 155,737,059 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,588,000 - 156,658,211 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,807,328 - 156,871,232 (+)NCBINCBI36Build 36hg18NCBI36
Build 344156,945,482 - 157,009,379NCBI
Celera4153,919,477 - 153,989,823 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4152,327,271 - 152,397,264 (+)NCBIHuRef
CHM1_14156,565,607 - 156,635,931 (+)NCBICHM1_1
T2T-CHM13v2.04158,999,647 - 159,069,856 (+)NCBIT2T-CHM13v2.0
Gucy1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39381,999,734 - 82,053,253 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl381,999,734 - 82,053,096 (-)EnsemblGRCm39 Ensembl
GRCm38382,092,427 - 82,145,946 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,092,427 - 82,145,789 (-)EnsemblGRCm38mm10GRCm38
MGSCv37381,896,349 - 81,949,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36382,178,354 - 82,231,000 (-)NCBIMGSCv36mm8
Celera382,117,270 - 82,170,809 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.97NCBI
Gucy1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82169,716,684 - 169,780,360 (-)NCBIGRCr8
mRatBN7.22167,418,615 - 167,482,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2167,418,640 - 167,481,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2174,618,756 - 174,679,844 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02172,639,998 - 172,701,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02167,227,585 - 167,288,671 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,045,703 - 181,102,918 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBICelera
Cytogenetic Map2q34NCBI
GUCY1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23153,578,326 - 153,648,905 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14153,933,876 - 154,004,517 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04148,032,167 - 148,102,757 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14159,850,092 - 159,920,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,850,107 - 159,913,338 (+)Ensemblpanpan1.1panPan2
GUCY1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11553,172,914 - 53,236,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1553,174,157 - 53,234,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,510,720 - 53,570,219 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01553,880,516 - 53,943,086 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1553,881,077 - 53,942,856 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11553,134,895 - 53,194,847 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01553,244,742 - 53,304,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01553,557,797 - 53,618,055 (+)NCBIUU_Cfam_GSD_1.0
Gucy1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,135,116 - 37,192,728 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365762,353,761 - 2,411,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365762,353,874 - 2,411,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl844,449,290 - 44,518,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1844,448,758 - 44,520,737 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2846,457,572 - 46,537,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17102,206,438 - 102,310,535 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7102,238,477 - 102,303,673 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603781,715,008 - 81,968,286 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gucy1a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248482,525,153 - 2,560,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248482,522,935 - 2,588,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016119   ⟹   ENSCLAP00000015955
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,424,273 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000016120   ⟹   ENSCLAP00000015956
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,422,452 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000016121   ⟹   ENSCLAP00000015957
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,396,406 (-)Ensembl
RefSeq Acc Id: XM_005400950   ⟹   XP_005401007
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547111,367,318 - 11,422,199 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401007 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015955.1
  ENSCLAP00000015956
  ENSCLAP00000015956.1
  ENSCLAP00000015957.1
Reference Protein Sequences
RefSeq Acc Id: XP_005401007   ⟸   XM_005400950
- UniProtKB: A0A8C2VKC1 (UniProtKB/TrEMBL),   A0A8C2VM42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015955   ⟸   ENSCLAT00000016119
RefSeq Acc Id: ENSCLAP00000015957   ⟸   ENSCLAT00000016121
RefSeq Acc Id: ENSCLAP00000015956   ⟸   ENSCLAT00000016120
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010980 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016119.1 UniProtKB/TrEMBL
  ENSCLAT00000016120 ENTREZGENE
  ENSCLAT00000016120.1 UniProtKB/TrEMBL
  ENSCLAT00000016121.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.260 UniProtKB/TrEMBL
  3.30.70.1230 UniProtKB/TrEMBL
  3.90.1520.10 UniProtKB/TrEMBL
  6.10.250.780 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  H-NOX_domain_sf UniProtKB/TrEMBL
  Heme_NO-bd UniProtKB/TrEMBL
  HNOB_dom_associated UniProtKB/TrEMBL
  HNOB_dom_associated_sf UniProtKB/TrEMBL
  NO_sig/Golgi_transp_ligand-bd UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Gucy1a3 ENTREZGENE
PANTHER GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-1 UniProtKB/TrEMBL
  GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 UniProtKB/TrEMBL
Pfam Guanylate_cyc UniProtKB/TrEMBL
  HNOB UniProtKB/TrEMBL
  HNOBA UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF111126 UniProtKB/TrEMBL
  SSF55073 UniProtKB/TrEMBL
UniProt A0A8C2VKC1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VM42 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-28 Gucy1a1  guanylate cyclase 1 soluble subunit alpha 1  Gucy1a3  guanylate cyclase 1 soluble subunit alpha  Symbol and/or name change 5135510 APPROVED
2016-08-03 Gucy1a3  guanylate cyclase 1 soluble subunit alpha    guanylate cyclase 1, soluble, alpha 3  Symbol and/or name change 5135510 APPROVED