Parp14 (poly(ADP-ribose) polymerase family member 14) - Rat Genome Database

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Gene: Parp14 (poly(ADP-ribose) polymerase family member 14) Chinchilla lanigera
Analyze
Symbol: Parp14
Name: poly(ADP-ribose) polymerase family member 14
RGD ID: 8901449
Description: ENCODES a protein that exhibits enzyme binding (ortholog); NAD+ ADP-ribosyltransferase activity (ortholog); NAD+ binding (ortholog); INVOLVED IN negative regulation of gene expression (ortholog); negative regulation of type II interferon-mediated signaling pathway (ortholog); negative regulation of tyrosine phosphorylation of STAT protein (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; interleukin-4 signaling pathway; ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly (ADP-ribose) polymerase family, member 14; poly [ADP-ribose] polymerase 14
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,879,740 - 21,927,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,878,980 - 21,929,097 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
plasma membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Parp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,879,740 - 21,927,883 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,878,980 - 21,929,097 (+)NCBIChiLan1.0ChiLan1.0
PARP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,680,839 - 122,730,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,680,839 - 122,730,840 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,399,686 - 122,449,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,882,362 - 123,932,377 (+)NCBINCBI36Build 36hg18NCBI36
Build 343123,900,859 - 123,932,376NCBI
Celera3120,809,505 - 120,859,520 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3119,772,932 - 119,822,958 (+)NCBIHuRef
CHM1_13122,363,227 - 122,413,244 (+)NCBICHM1_1
T2T-CHM13v2.03125,400,088 - 125,450,091 (+)NCBIT2T-CHM13v2.0
Parp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,652,262 - 35,691,904 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,653,244 - 35,691,914 (-)EnsemblGRCm39 Ensembl
GRCm381635,831,892 - 35,871,518 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,832,874 - 35,871,544 (-)EnsemblGRCm38mm10GRCm38
MGSCv371635,832,964 - 35,871,468 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,752,625 - 35,791,247 (-)NCBIMGSCv36mm8
Celera1636,312,784 - 36,351,557 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.43NCBI
Parp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,408,134 - 78,440,201 (+)NCBIGRCr8
mRatBN7.21164,902,848 - 64,934,916 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,902,785 - 64,934,916 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,724,829 - 73,756,951 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,387,099 - 66,419,216 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,418,357 - 65,450,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,105,442 - 68,137,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,105,369 - 68,137,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,194,913 - 71,226,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,736,902 - 66,768,977 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,800,714 - 66,824,843 (+)NCBI
Celera1164,365,191 - 64,397,200 (+)NCBICelera
Cytogenetic Map11q22NCBI
PARP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,630,429 - 120,680,952 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,635,379 - 120,685,731 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,773,334 - 119,823,732 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,677,868 - 126,728,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,677,868 - 126,728,256 (+)Ensemblpanpan1.1panPan2
PARP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,763,282 - 25,798,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,763,255 - 25,798,198 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,787,251 - 25,824,358 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,996,942 - 26,033,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,996,843 - 26,031,731 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,794,923 - 25,831,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,836,951 - 25,874,257 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,396,287 - 26,433,388 (+)NCBIUU_Cfam_GSD_1.0
LOC101962583
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,548,280 - 128,598,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,923,411 - 8,974,283 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,923,398 - 8,976,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,809,510 - 137,865,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,809,499 - 137,865,383 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213147,430,086 - 147,483,561 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PARP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,135,092 - 58,185,988 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,134,973 - 58,185,521 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,163,757 - 108,215,859 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912969,236 - 1,023,564 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912969,144 - 1,022,506 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014466   ⟹   ENSCLAP00000014308
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542721,879,740 - 21,927,883 (+)Ensembl
RefSeq Acc Id: XM_005386519   ⟹   XP_005386576
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,878,980 - 21,929,097 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515129   ⟹   XP_013370583
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542721,887,203 - 21,929,097 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386576 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370583 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000014308
  ENSCLAP00000014308.1
Reference Protein Sequences
RefSeq Acc Id: XP_005386576   ⟸   XM_005386519
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VLE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370583   ⟸   XM_013515129
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000014308   ⟸   ENSCLAT00000014466
Protein Domains
Macro   PARP catalytic   WWE


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009862 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014466 ENTREZGENE
  ENSCLAT00000014466.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  3.30.720.50 UniProtKB/TrEMBL
  3.40.220.10 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
InterPro Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
NCBI Gene Parp14 ENTREZGENE
PANTHER PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14 UniProtKB/TrEMBL
Pfam Macro UniProtKB/TrEMBL
  PARP UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/TrEMBL
  PARP_CATALYTIC UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
SMART A1pp UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF117839 UniProtKB/TrEMBL
  SSF52949 UniProtKB/TrEMBL
UniProt A0A8C2VLE0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Parp14  poly(ADP-ribose) polymerase family member 14    poly (ADP-ribose) polymerase family, member 14  Symbol and/or name change 5135510 APPROVED