Dguok (deoxyguanosine kinase) - Rat Genome Database

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Gene: Dguok (deoxyguanosine kinase) Chinchilla lanigera
Analyze
Symbol: Dguok
Name: deoxyguanosine kinase
RGD ID: 8894547
Description: ENCODES a protein that exhibits deoxyadenosine kinase activity (ortholog); deoxyguanosine kinase activity (ortholog); deoxynucleoside kinase activity (ortholog); INVOLVED IN dAMP salvage (ortholog); deoxyribonucleoside monophosphate biosynthetic process (ortholog); dGTP metabolic process (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 4 (ortholog); Cognitive Dysfunction (ortholog); congenital disorder of glycosylation type IIb (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: deoxyguanosine kinase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,738,859 - 11,773,902 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,739,904 - 11,773,884 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
mitochondrion  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dguok
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,738,859 - 11,773,902 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,739,904 - 11,773,884 (-)NCBIChiLan1.0ChiLan1.0
DGUOK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38273,926,880 - 73,958,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl273,926,826 - 73,958,961 (+)EnsemblGRCh38hg38GRCh38
GRCh37274,154,007 - 74,186,073 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,007,461 - 74,039,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 34274,065,607 - 74,097,743NCBI
Celera273,985,216 - 74,017,351 (+)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef273,889,617 - 73,921,742 (+)NCBIHuRef
CHM1_1274,083,278 - 74,115,396 (+)NCBICHM1_1
T2T-CHM13v2.0273,935,347 - 73,967,403 (+)NCBIT2T-CHM13v2.0
Dguok
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,457,199 - 83,483,887 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,457,199 - 83,483,951 (-)EnsemblGRCm39 Ensembl
GRCm38683,480,214 - 83,506,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,480,217 - 83,506,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,430,208 - 83,456,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,445,875 - 83,472,552 (-)NCBIMGSCv36mm8
Celera685,461,324 - 85,488,129 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Dguok
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,544,784 - 117,572,414 (-)NCBIGRCr8
mRatBN7.24115,987,101 - 116,014,733 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,979,094 - 116,014,733 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,465,198 - 121,493,156 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04117,240,371 - 117,268,329 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,854,010 - 115,881,956 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04115,180,433 - 115,208,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4115,180,433 - 115,208,061 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,770,727 - 179,798,683 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,697,251 - 117,725,383 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14117,942,451 - 117,969,809 (-)NCBI
Celera4104,980,935 - 105,008,470 (-)NCBICelera
Cytogenetic Map4q34NCBI
DGUOK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21252,424,898 - 52,456,909 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A52,427,652 - 52,459,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A74,000,969 - 74,032,993 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,510,768 - 75,542,563 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,510,768 - 75,542,563 (+)Ensemblpanpan1.1panPan2
DGUOK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,107,085 - 49,139,366 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,104,546 - 49,168,782 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,747,777 - 48,780,029 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01749,966,601 - 49,998,895 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1749,966,603 - 49,999,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11748,982,805 - 49,015,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01749,049,971 - 49,082,509 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,608,020 - 49,640,318 (-)NCBIUU_Cfam_GSD_1.0
Dguok
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,474,072 - 10,511,248 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936556226,627 - 264,905 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936556226,643 - 263,517 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DGUOK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,054,761 - 69,091,341 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,054,749 - 69,091,366 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2372,209,549 - 72,245,858 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DGUOK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11433,320,957 - 33,356,088 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1433,320,969 - 33,356,093 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604578,811,375 - 78,845,097 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dguok
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474929,516,229 - 29,561,220 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474929,494,866 - 29,560,887 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000017712   ⟹   ENSCLAP00000017540
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542411,738,859 - 11,773,902 (-)Ensembl
RefSeq Acc Id: XM_005385533   ⟹   XP_005385590
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542411,739,904 - 11,773,880 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005385534   ⟹   XP_005385591
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542411,739,904 - 11,773,884 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005385590 (Get FASTA)   NCBI Sequence Viewer  
  XP_005385591 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017540
  ENSCLAP00000017540.1
RefSeq Acc Id: XP_005385591   ⟸   XM_005385534
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005385590   ⟸   XM_005385533
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VNY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017540   ⟸   ENSCLAT00000017712
Protein Domains
Deoxynucleoside kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012038 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017712 ENTREZGENE
  ENSCLAT00000017712.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DCK/DGK UniProtKB/TrEMBL
  DNK_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Dguok ENTREZGENE
PANTHER DEOXYGUANOSINE KINASE, MITOCHONDRIAL UniProtKB/TrEMBL
  DEOXYNUCLEOSIDE KINASE UniProtKB/TrEMBL
Pfam dNK UniProtKB/TrEMBL
PIRSF DNK UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VNY9 ENTREZGENE, UniProtKB/TrEMBL