Ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) - Rat Genome Database

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Gene: Ywhaq (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) Chinchilla lanigera
Analyze
Symbol: Ywhaq
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
RGD ID: 8888436
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of monoatomic ion transmembrane transport (ortholog); protein targeting (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH genetic disease (ortholog); NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, HYPOTONIA, NYSTAGMUS, AND SEIZURES (ortholog); osteoarthritis (ortholog); FOUND IN cytoplasm (ortholog); protein-containing complex (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,230,506 - 5,263,752 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,229,485 - 5,263,749 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ywhaq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,230,506 - 5,263,752 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,229,485 - 5,263,749 (-)NCBIChiLan1.0ChiLan1.0
YWHAQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,583,967 - 9,630,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl29,583,967 - 9,630,997 (-)EnsemblGRCh38hg38GRCh38
GRCh3729,724,096 - 9,771,126 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,641,557 - 9,688,557 (-)NCBINCBI36Build 36hg18NCBI36
Build 3429,674,703 - 9,721,704NCBI
Celera29,635,980 - 9,682,954 (-)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,569,609 - 9,616,664 (-)NCBIHuRef
CHM1_129,653,476 - 9,700,564 (-)NCBICHM1_1
T2T-CHM13v2.029,609,000 - 9,656,011 (-)NCBIT2T-CHM13v2.0
Ywhaq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,440,330 - 21,467,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,440,072 - 21,467,638 (-)EnsemblGRCm39 Ensembl
GRCm381221,390,329 - 21,417,436 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1221,390,071 - 21,417,637 (-)EnsemblGRCm38mm10GRCm38
MGSCv371221,396,190 - 21,423,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361221,636,819 - 21,663,926 (-)NCBIMGSCv36mm8
Celera1219,483,848 - 19,511,370 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.31NCBI
Ywhaq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,664,358 - 46,694,875 (-)NCBIGRCr8
mRatBN7.2640,935,714 - 40,966,240 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,935,949 - 40,966,273 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx641,257,806 - 41,288,261 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0641,572,495 - 41,602,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0641,005,763 - 41,036,210 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0643,463,294 - 43,493,816 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,463,294 - 43,493,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,331,003 - 60,361,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,945,769 - 41,976,123 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,948,894 - 41,979,249 (-)NCBI
Celera640,222,774 - 40,252,668 (-)NCBICelera
Cytogenetic Map6q16NCBI
YWHAQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212116,895,271 - 116,943,104 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A116,899,244 - 116,946,787 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,573,413 - 9,620,495 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A9,735,448 - 9,772,074 (-)NCBIpanpan1.1PanPan1.1panPan2
YWHAQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,660,504 - 6,697,954 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,588,178 - 6,625,624 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0176,759,032 - 6,796,562 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,758,751 - 6,796,522 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,651,427 - 6,688,863 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,653,706 - 6,691,132 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,667,564 - 6,705,013 (-)NCBIUU_Cfam_GSD_1.0
Ywhaq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629251,176,636 - 51,199,301 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365325,931,677 - 5,938,569 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,738,862 - 126,772,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,738,795 - 126,772,784 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,245,481 - 135,278,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAQ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,017,300 - 98,064,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604514,257,939 - 14,305,505 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhaq
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969167,676 - 199,963 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624969167,635 - 199,963 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005130   ⟹   ENSCLAP00000005037
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554875,230,506 - 5,263,752 (-)Ensembl
RefSeq Acc Id: XM_005404398   ⟹   XP_005404455
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554875,229,485 - 5,263,749 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404455 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005037.1
Reference Protein Sequences
RefSeq Acc Id: XP_005404455   ⟸   XM_005404398
- UniProtKB: A0A8C2UTG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005037   ⟸   ENSCLAT00000005130
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003576 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005130.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/TrEMBL
NCBI Gene Ywhaq ENTREZGENE
PANTHER 14-3-3 PROTEIN ZETA UniProtKB/TrEMBL
  PTHR18860 UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/TrEMBL
  1433_2 UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/TrEMBL
UniProt A0A8C2UTG3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ywhaq  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta  Symbol and/or name change 5135510 APPROVED
2015-08-25 Ywhaq  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide  Symbol and/or name change 5135510 APPROVED