Ghr (growth hormone receptor) - Rat Genome Database

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Pathways
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Gene: Ghr (growth hormone receptor) Chinchilla lanigera
Analyze
Symbol: Ghr
Name: growth hormone receptor
RGD ID: 8874749
Description: ENCODES a protein that exhibits growth factor binding (ortholog); growth hormone receptor activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of Janus kinase activity (ortholog); cartilage development involved in endochondral bone morphogenesis (ortholog); cell surface receptor signaling pathway via JAK-STAT (ortholog); PARTICIPATES IN growth hormone signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Brain Hypoxia-Ischemia (ortholog); breast cancer (ortholog); FOUND IN cell surface (ortholog); cytoplasmic ribonucleoprotein granule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542626,689,581 - 26,871,684 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542626,553,509 - 26,873,619 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ghr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542626,689,581 - 26,871,684 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542626,553,509 - 26,873,619 (+)NCBIChiLan1.0ChiLan1.0
GHR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38542,423,439 - 42,721,878 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl542,423,439 - 42,721,878 (+)EnsemblGRCh38hg38GRCh38
GRCh37542,423,541 - 42,721,980 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36542,459,783 - 42,757,683 (+)NCBINCBI36Build 36hg18NCBI36
Build 34542,459,782 - 42,757,682NCBI
Celera542,314,115 - 42,611,474 (+)NCBICelera
Cytogenetic Map5p13.1-p12NCBI
HuRef542,375,464 - 42,673,429 (+)NCBIHuRef
CHM1_1542,425,901 - 42,723,964 (+)NCBICHM1_1
T2T-CHM13v2.0542,678,916 - 42,974,806 (+)NCBIT2T-CHM13v2.0
Ghr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,347,237 - 3,612,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,347,242 - 3,612,974 (-)EnsemblGRCm39 Ensembl
GRCm38153,317,755 - 3,583,352 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,317,760 - 3,583,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37153,267,760 - 3,533,230 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36153,267,774 - 3,533,231 (-)NCBIMGSCv36mm8
Celera153,182,321 - 3,448,882 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.84NCBI
Ghr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8254,269,066 - 54,532,595 (-)NCBIGRCr8
mRatBN7.2252,541,452 - 52,804,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl252,542,594 - 52,804,735 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx259,642,577 - 59,799,676 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0257,701,311 - 57,858,396 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0252,732,297 - 52,881,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0253,149,225 - 53,413,954 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,150,370 - 53,413,638 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0272,265,571 - 72,346,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0272,182,692 - 72,218,250 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4252,496,517 - 52,658,066 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1252,424,749 - 52,586,299 (-)NCBI
Celera248,257,266 - 48,408,640 (-)NCBICelera
RH 3.4 Map2332.2RGD
Cytogenetic Map2q16NCBI
GHR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2467,606,168 - 67,904,442 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1565,759,794 - 66,082,475 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0567,654,326 - 67,953,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1572,700,150 - 72,997,356 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl572,700,150 - 72,871,278 (-)Ensemblpanpan1.1panPan2
GHR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1467,021,821 - 67,245,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl467,022,252 - 67,290,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha466,705,544 - 66,845,096 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0467,531,090 - 67,802,322 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl467,532,966 - 67,802,335 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1467,276,975 - 67,416,597 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0467,407,363 - 67,546,744 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0467,943,814 - 68,083,513 (-)NCBIUU_Cfam_GSD_1.0
Ghr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213230,991,608 - 231,135,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936518235,990 - 380,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936518235,996 - 380,225 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GHR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1627,126,734 - 27,421,449 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11627,126,300 - 27,422,618 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21628,691,739 - 28,855,136 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GHR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1441,171,038 - 41,464,474 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl441,285,712 - 41,464,666 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607131,608,844 - 31,907,481 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ghr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475912,285,594 - 12,570,906 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475912,282,295 - 12,570,106 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013514982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013514983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF332036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF520660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01026786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY701337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBBH01051006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBCE01118144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000021936   ⟹   ENSCLAP00000021733
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542626,689,581 - 26,871,684 (+)Ensembl
RefSeq Acc Id: XM_013514982   ⟹   XP_013370436
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542626,553,509 - 26,873,614 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514983   ⟹   XP_013370437
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542626,674,409 - 26,873,619 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013370436 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370437 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK71912 (Get FASTA)   NCBI Sequence Viewer  
  AAO73203 (Get FASTA)   NCBI Sequence Viewer  
  AAU06306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021733
  ENSCLAP00000021733.1
Reference Protein Sequences
RefSeq Acc Id: XP_013370436   ⟸   XM_013514982
- UniProtKB: A0A8C2W1R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370437   ⟸   XM_013514983
- UniProtKB: A0A8C2W1R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021733   ⟸   ENSCLAT00000021936
Protein Domains
Growth hormone-binding protein   Growth hormone/erythropoietin receptor ligand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014878 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021936 ENTREZGENE
  ENSCLAT00000021936.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  GHBP UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
NCBI Gene Ghr ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  GROWTH HORMONE RECEPTOR UniProtKB/TrEMBL
Pfam EpoR_lig-bind UniProtKB/TrEMBL
  GHBP UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A8C2W1R5 ENTREZGENE, UniProtKB/TrEMBL
  Q66VY2_CHILA UniProtKB/TrEMBL
  Q924F1_CHILA UniProtKB/TrEMBL