Stk3 (serine/threonine kinase 3) - Rat Genome Database

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Gene: Stk3 (serine/threonine kinase 3) Chinchilla lanigera
Analyze
Symbol: Stk3
Name: serine/threonine kinase 3
RGD ID: 8859285
Description: ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN apoptotic process (ortholog); canonical Wnt signaling pathway (ortholog); cell differentiation involved in embryonic placenta development (ortholog); ASSOCIATED WITH Cohen syndrome (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541714,095,694 - 14,381,607 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541714,098,851 - 14,381,553 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Stk3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541714,095,694 - 14,381,607 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541714,098,851 - 14,381,553 (-)NCBIChiLan1.0ChiLan1.0
STK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38898,343,975 - 98,942,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl898,371,228 - 98,942,827 (-)EnsemblGRCh38hg38GRCh38
GRCh37899,466,861 - 99,954,838 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36899,536,037 - 99,907,085 (-)NCBINCBI36Build 36hg18NCBI36
Build 34899,536,042 - 99,907,085NCBI
Celera895,652,680 - 96,023,711 (-)NCBICelera
Cytogenetic Map8q22.2NCBI
HuRef894,670,086 - 95,157,575 (-)NCBIHuRef
CHM1_1899,507,181 - 99,995,466 (-)NCBICHM1_1
T2T-CHM13v2.0899,469,462 - 100,069,002 (-)NCBIT2T-CHM13v2.0
Stk3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391534,875,645 - 35,155,990 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1534,875,642 - 35,179,067 (-)EnsemblGRCm39 Ensembl
GRCm381534,875,499 - 35,155,882 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1534,875,496 - 35,178,921 (-)EnsemblGRCm38mm10GRCm38
MGSCv371534,805,254 - 35,085,561 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361534,821,196 - 35,100,274 (-)NCBIMGSCv36mm8
Celera1535,503,253 - 35,772,245 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.34NCBI
Stk3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8767,938,341 - 68,208,472 (-)NCBIGRCr8
mRatBN7.2766,053,209 - 66,323,292 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl766,052,345 - 66,323,233 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx767,942,463 - 68,211,608 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0770,144,143 - 70,414,225 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0770,017,776 - 70,274,776 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0773,617,926 - 73,883,896 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl773,618,644 - 73,883,812 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0773,793,705 - 74,055,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4770,308,195 - 70,597,445 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1770,447,334 - 70,618,175 (-)NCBI
Celera763,152,608 - 63,416,831 (-)NCBICelera
Cytogenetic Map7q22NCBI
STK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27115,664,689 - 116,170,207 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1891,344,435 - 91,711,597 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0895,098,185 - 95,465,324 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1897,278,139 - 97,592,727 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl897,355,173 - 97,708,437 (-)Ensemblpanpan1.1panPan2
STK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.113647,363 - 920,887 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl13648,216 - 920,847 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha13640,435 - 1,015,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.013796,957 - 1,172,656 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl13796,966 - 1,070,759 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.113639,257 - 1,015,142 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.013747,613 - 1,123,107 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.013753,947 - 1,129,925 (-)NCBIUU_Cfam_GSD_1.0
Stk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530336,733,336 - 37,010,196 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647044,159,419 - 44,436,330 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647044,159,449 - 44,436,295 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl438,011,814 - 38,306,773 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1438,011,802 - 38,306,777 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2441,016,047 - 41,330,062 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1893,374,528 - 93,698,143 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl893,374,517 - 93,697,758 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603947,027,424 - 47,360,853 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stk3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247635,564,835 - 5,886,769 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247635,568,079 - 5,886,722 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000017673   ⟹   ENSCLAP00000017501
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541714,095,694 - 14,381,607 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000017674   ⟹   ENSCLAP00000017502
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541714,100,032 - 14,381,314 (-)Ensembl
RefSeq Acc Id: XM_005381850   ⟹   XP_005381907
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541714,098,851 - 14,381,553 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005381851   ⟹   XP_005381908
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541714,098,851 - 14,381,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512823   ⟹   XP_013368277
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541714,098,851 - 14,335,914 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381907 (Get FASTA)   NCBI Sequence Viewer  
  XP_005381908 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368277 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017501
  ENSCLAP00000017501.1
  ENSCLAP00000017502.1
RefSeq Acc Id: XP_005381907   ⟸   XM_005381850
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VLW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005381908   ⟸   XM_005381851
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YR99 (UniProtKB/TrEMBL),   A0A8C2VLW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368277   ⟸   XM_013512823
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VLW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017501   ⟸   ENSCLAT00000017673
RefSeq Acc Id: ENSCLAP00000017502   ⟸   ENSCLAT00000017674
Protein Domains
Protein kinase   SARAH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012018 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017673 ENTREZGENE
  ENSCLAT00000017673.1 UniProtKB/TrEMBL
  ENSCLAT00000017674.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.4270 UniProtKB/TrEMBL
  4.10.170.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Mst1_SARAH_domain UniProtKB/TrEMBL
  p53_tetramer_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  SARAH_dom UniProtKB/TrEMBL
NCBI Gene Stk3 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE 3 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TAO UniProtKB/TrEMBL
Pfam Mst1_SARAH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  SARAH UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VLW5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YR99 ENTREZGENE, UniProtKB/TrEMBL