Akap13 (A-kinase anchoring protein 13) - Rat Genome Database

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Gene: Akap13 (A-kinase anchoring protein 13) Chinchilla lanigera
Analyze
Symbol: Akap13
Name: A-kinase anchoring protein 13
RGD ID: 8822607
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); MAP-kinase scaffold activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (ortholog); adrenergic receptor signaling pathway (ortholog); bone development (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Esophageal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); actin filament (ortholog); cell cortex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A kinase (PRKA) anchor protein 13; A-kinase anchor protein 13
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,247,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Akap13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,247,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBIChiLan1.0ChiLan1.0
AKAP13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381585,380,603 - 85,749,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1585,380,571 - 85,749,358 (+)EnsemblGRCh38hg38GRCh38
GRCh371585,923,834 - 86,292,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361583,724,875 - 84,093,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341584,021,271 - 84,093,590NCBI
Celera1562,323,846 - 62,692,414 (+)NCBICelera
Cytogenetic Map15q25.3NCBI
HuRef1561,986,401 - 62,354,887 (+)NCBIHuRef
CHM1_11585,765,298 - 86,134,016 (+)NCBICHM1_1
T2T-CHM13v2.01583,132,647 - 83,501,376 (+)NCBIT2T-CHM13v2.0
Akap13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39775,105,271 - 75,404,357 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl775,105,282 - 75,404,357 (+)EnsemblGRCm39 Ensembl
GRCm38775,455,526 - 75,754,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl775,455,534 - 75,754,609 (+)EnsemblGRCm38mm10GRCm38
MGSCv37782,600,420 - 82,899,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36775,328,812 - 75,628,122 (+)NCBIMGSCv36mm8
Celera772,913,871 - 73,205,960 (+)NCBICelera
Cytogenetic Map7D1NCBI
cM Map743.76NCBI
Akap13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81138,722,445 - 139,029,401 (+)NCBIGRCr8
mRatBN7.21129,313,183 - 129,619,647 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1129,314,402 - 129,619,646 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1137,232,876 - 137,538,333 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01144,403,105 - 144,708,592 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,289,702 - 137,597,080 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,089,558 - 137,315,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,014,272 - 137,315,272 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,007,112 - 138,312,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,052,674 - 131,360,512 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,302,912 - 131,380,987 (+)NCBI
Celera1121,422,303 - 121,727,463 (+)NCBICelera
Cytogenetic Map1q31NCBI
AKAP13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21674,930,726 - 75,292,650 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11578,635,626 - 78,997,324 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01564,076,422 - 64,438,109 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11583,289,867 - 83,651,362 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1583,387,667 - 83,651,362 (+)Ensemblpanpan1.1panPan2
AKAP13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1349,076,313 - 49,310,564 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl349,076,642 - 49,308,221 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha351,631,494 - 51,952,108 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0349,413,000 - 49,733,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl349,412,925 - 49,729,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1348,911,383 - 49,227,381 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0349,139,636 - 49,460,216 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0349,485,435 - 49,806,458 (+)NCBIUU_Cfam_GSD_1.0
Akap13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640134,357,191 - 134,672,629 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648311,661,862 - 11,977,292 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1787,889,384 - 88,222,854 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2794,486,955 - 94,583,014 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AKAP13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1294,009,921 - 4,364,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl294,106,732 - 4,359,516 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605942,653,071 - 43,006,115 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476812,765,723 - 13,095,136 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476812,767,120 - 13,099,288 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005381591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013512530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013512531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013512532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013512533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013512534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01017414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01017422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBCE01117069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000013347   ⟹   ENSCLAP00000013196
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,247,626 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000013348   ⟹   ENSCLAP00000013197
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,247,626 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000013349   ⟹   ENSCLAP00000013198
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541619,009,485 - 19,115,489 (-)Ensembl
RefSeq Acc Id: XM_005381591   ⟹   XP_005381648
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512530   ⟹   XP_013367984
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512531   ⟹   XP_013367985
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512532   ⟹   XP_013367986
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512533   ⟹   XP_013367987
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,327,523 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512534   ⟹   XP_013367988
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541619,006,206 - 19,116,136 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005381648   ⟸   XM_005381591
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VH11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367987   ⟸   XM_013512533
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013367986   ⟸   XM_013512532
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013367985   ⟸   XM_013512531
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013367984   ⟸   XM_013512530
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VDX4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367988   ⟸   XM_013512534
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VBP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000013196   ⟸   ENSCLAT00000013347
RefSeq Acc Id: ENSCLAP00000013197   ⟸   ENSCLAT00000013348
RefSeq Acc Id: ENSCLAP00000013198   ⟸   ENSCLAT00000013349
Protein Domains
DH   PH   Phorbol-ester/DAG-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009112 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013347 ENTREZGENE
  ENSCLAT00000013347.1 UniProtKB/TrEMBL
  ENSCLAT00000013348 ENTREZGENE
  ENSCLAT00000013348.1 UniProtKB/TrEMBL
  ENSCLAT00000013349 ENTREZGENE
  ENSCLAT00000013349.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_16 UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Akap13 ENTREZGENE
PANTHER AGAP007712-PA UniProtKB/TrEMBL
  PTHR13944:SF18 UniProtKB/TrEMBL
Pfam PH_16 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A8C2VBP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VDX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VH11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Akap13  A-kinase anchoring protein 13    A kinase (PRKA) anchor protein 13  Symbol and/or name change 5135510 APPROVED