Aoc1 (amine oxidase copper containing 1) - Rat Genome Database

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Gene: Aoc1 (amine oxidase copper containing 1) Chinchilla lanigera
Analyze
Symbol: Aoc1
Name: amine oxidase copper containing 1
RGD ID: 8811747
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); copper ion binding (ortholog); diamine oxidase activity (ortholog); INVOLVED IN putrescine metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); Cardiomegaly (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN bicellular tight junction (ortholog); extracellular exosome (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amiloride-sensitive amine oxidase [copper-containing]; amine oxidase, copper containing 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,316,476 - 5,326,305 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,316,482 - 5,326,262 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Aoc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,316,476 - 5,326,305 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,316,482 - 5,326,262 (+)NCBIChiLan1.0ChiLan1.0
AOC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387150,852,120 - 150,861,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7150,824,627 - 150,861,504 (+)EnsemblGRCh38hg38GRCh38
GRCh377150,549,605 - 150,558,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,180,506 - 150,189,312 (+)NCBINCBI36Build 36hg18NCBI36
Build 347149,987,239 - 149,996,025NCBI
Celera7145,106,596 - 145,115,402 (+)NCBICelera
Cytogenetic Map7q36.1ENTREZGENE
HuRef7144,361,610 - 144,370,427 (+)NCBIHuRef
CHM1_17150,557,803 - 150,566,593 (+)NCBICHM1_1
T2T-CHM13v2.07152,025,287 - 152,034,270 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27149,878,851 - 149,887,665 (+)NCBI
Aoc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39648,872,189 - 48,886,122 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl648,849,830 - 48,886,122 (+)EnsemblGRCm39 Ensembl
GRCm38648,895,255 - 48,909,188 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl648,872,896 - 48,909,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv37648,845,254 - 48,859,186 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36648,824,840 - 48,838,774 (+)NCBIMGSCv36mm8
Celera649,405,009 - 49,418,946 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map623.78NCBI
Aoc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,143,126 - 79,162,705 (+)NCBIGRCr8
mRatBN7.2477,812,260 - 77,831,846 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl477,812,260 - 77,831,840 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx483,019,777 - 83,039,389 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0478,795,250 - 78,814,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0477,235,544 - 77,255,152 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0478,496,043 - 78,515,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,496,043 - 78,515,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04143,183,686 - 143,203,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4476,957,477 - 76,977,643 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1477,247,444 - 77,253,779 (+)NCBI
Celera472,749,277 - 72,768,814 (+)NCBICelera
Cytogenetic Map4q24NCBI
AOC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,267,472 - 187,277,116 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,278,074 - 39,286,395 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07142,434,732 - 142,443,050 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17154,586,931 - 154,595,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,563,523 - 154,595,248 (+)Ensemblpanpan1.1panPan2
AOC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11614,955,528 - 14,963,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1614,958,658 - 15,036,651 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,563,706 - 15,571,546 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01616,671,139 - 16,678,130 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11615,049,911 - 15,057,763 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01615,631,448 - 15,639,287 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01615,681,981 - 15,689,844 (+)NCBIUU_Cfam_GSD_1.0
Aoc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,590,547 - 6,597,512 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,308,682 - 6,312,815 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,309,210 - 6,312,869 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AOC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,309,594 - 6,320,974 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,309,583 - 6,321,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,738,053 - 6,749,392 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AOC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,037,498 - 119,046,875 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,038,356 - 119,047,279 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,014,229 - 15,018,767 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aoc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,739,034 - 5,749,608 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248005,739,076 - 5,749,567 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001986   ⟹   ENSCLAP00000001941
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554915,316,476 - 5,326,305 (+)Ensembl
RefSeq Acc Id: XM_005404798   ⟹   XP_005404855
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,316,482 - 5,326,262 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504575   ⟹   XP_013360029
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,316,501 - 5,326,262 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404855 (Get FASTA)   NCBI Sequence Viewer  
  XP_013360029 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001941
  ENSCLAP00000001941.1
Reference Protein Sequences
RefSeq Acc Id: XP_005404855   ⟸   XM_005404798
- UniProtKB: A0A8C2YIV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360029   ⟸   XM_013504575
- UniProtKB: A0A8C2YIV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001941   ⟸   ENSCLAT00000001986
Protein Domains
Copper amine oxidase catalytic   Copper amine oxidase N2-terminal   Copper amine oxidase N3-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001431 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001986 ENTREZGENE
  ENSCLAT00000001986.1 UniProtKB/TrEMBL
Gene3D-CATH 2.70.98.20 UniProtKB/TrEMBL
  3.10.450.40 UniProtKB/TrEMBL
InterPro Cu_amine_oxidase UniProtKB/TrEMBL
  Cu_amine_oxidase_C UniProtKB/TrEMBL
  Cu_amine_oxidase_C_sf UniProtKB/TrEMBL
  Cu_amine_oxidase_N-reg UniProtKB/TrEMBL
  Cu_amine_oxidase_N2 UniProtKB/TrEMBL
  Cu_amine_oxidase_N3 UniProtKB/TrEMBL
NCBI Gene Aoc1 ENTREZGENE
PANTHER AMILORIDE-SENSITIVE AMINE OXIDASE [COPPER-CONTAINING] UniProtKB/TrEMBL
  PTHR10638 UniProtKB/TrEMBL
Pfam Cu_amine_oxid UniProtKB/TrEMBL
  Cu_amine_oxidN2 UniProtKB/TrEMBL
  Cu_amine_oxidN3 UniProtKB/TrEMBL
PRINTS CUDAOXIDASE UniProtKB/TrEMBL
PROSITE COPPER_AMINE_OXID_1 UniProtKB/TrEMBL
  COPPER_AMINE_OXID_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF49998 UniProtKB/TrEMBL
  SSF54416 UniProtKB/TrEMBL
UniProt A0A8C2YIV8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-22 Aoc1  amine oxidase copper containing 1    amine oxidase, copper containing 1  Symbol and/or name change 5135510 APPROVED