Gstm4 (glutathione S-transferase mu 4)

Gene: Gstm4 (glutathione S-transferase mu 4) Chinchilla lanigera

Analyze

Symbol:

Gstm4 (Ensembl: GSTM2)

Name:

glutathione S-transferase mu 4

RGD ID:

8809774

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); glutathione binding (ortholog); glutathione transferase activity (ortholog); INVOLVED IN glutathione metabolic process (ortholog); long-chain fatty acid biosynthetic process (ortholog); nitrobenzene metabolic process (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); intercellular bridge (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,210,264 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	13,064,691 - 13,069,734 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Chemical and Drug Induced Liver Injury (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 63 (ISO)

neurodegenerative disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutathione metabolic process (ISO)

long-chain fatty acid biosynthetic process (ISO)

nitrobenzene metabolic process (ISO)

xenobiotic catabolic process (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

intercellular bridge (ISO)

Molecular Function

enzyme binding (ISO)

glutathione binding (ISO)

glutathione transferase activity (ISO)

leukotriene-C4 synthase activity (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Gstm4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,210,264 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	13,064,691 - 13,069,734 (+)	NCBI	ChiLan1.0	ChiLan1.0

GSTM4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	109,656,099 - 109,667,727 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	109,656,099 - 109,665,496 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	110,198,721 - 110,208,119 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	110,000,226 - 110,009,648 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	108,463,772 - 108,473,180 (+)	NCBI		Celera
Cytogenetic Map	1	p13.3	NCBI
HuRef	1	108,086,984 - 108,096,416 (+)	NCBI		HuRef
CHM1_1	1	110,313,519 - 110,322,944 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	109,684,537 - 109,696,166 (+)	NCBI		T2T-CHM13v2.0

Gstm4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	107,937,887 - 107,952,495 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	107,947,724 - 107,952,210 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	108,030,571 - 108,045,179 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	108,040,408 - 108,044,894 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	107,843,326 - 107,847,777 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	108,168,464 - 108,172,845 (-)	NCBI		MGSCv36	mm8
Celera	3	110,373,991 - 110,378,442 (-)	NCBI		Celera
Cytogenetic Map	3	F2.3	NCBI
cM Map	3	46.83	NCBI

Gstm4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	198,356,114 - 198,373,487 (-)	NCBI		GRCr8
mRatBN7.2	2	195,667,940 - 195,685,315 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	195,680,004 - 195,685,323 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	203,322,478 - 203,327,732 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	201,204,594 - 201,209,850 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	196,021,555 - 196,026,811 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	210,834,013 - 210,839,242 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	210,833,884 - 210,839,295 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	230,302,889 - 230,308,113 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	203,605,593 - 203,610,817 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	188,325,385 - 188,330,613 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

GSTM4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	117,629,559 - 117,648,713 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	116,774,969 - 116,808,377 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	112,033,462 - 112,337,606 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	111,261,585 - 111,270,912 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	111,261,585 - 111,270,919 (+)	Ensembl	panpan1.1		panPan2

LOC479912
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	42,201,697 - 42,207,886 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	44,977,327 - 44,983,514 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	42,533,367 - 42,539,560 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	42,534,290 - 42,539,704 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	42,266,138 - 42,272,342 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	42,223,891 - 42,230,078 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	42,658,872 - 42,665,063 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101958900
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	18,963,655 - 18,971,183 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936704	1,143,010 - 1,148,567 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936704	1,142,990 - 1,150,491 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC106510200
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	4	110,378,016 - 110,413,483 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	120,750,531 - 120,784,580 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005388891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01033177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01012055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000016740 ⟹ ENSCLAP00000016576

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,183,942 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016741 ⟹ ENSCLAP00000016577

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,175,862 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016742 ⟹ ENSCLAP00000016578

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,175,862 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016743 ⟹ ENSCLAP00000016579

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,063,966 - 13,070,414 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016744 ⟹ ENSCLAP00000016580

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,090,255 - 13,183,942 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016745 ⟹ ENSCLAP00000016581

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,090,255 - 13,175,862 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016746 ⟹ ENSCLAP00000016582

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,099,364 - 13,210,264 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016747 ⟹ ENSCLAP00000016583

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,099,364 - 13,210,264 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016748 ⟹ ENSCLAP00000016584

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,099,364 - 13,183,942 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000016749 ⟹ ENSCLAP00000016585

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955435	13,200,085 - 13,210,264 (+)	Ensembl

RefSeq Acc Id:

XM_005388891 ⟹ XP_005388948

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955435	13,064,691 - 13,069,734 (+)	NCBI

Sequence:

show sequence

GTTGGAGCTAAGCAGTTCTGGCCTCCGGGTGAGGCTCTCCAGGCCTCGCCCAGCGCTCTTGGGC
CCCGAGGGTGAAGTCACAGCTTAGTGCTGCTGAGGGCATTTGGCTCAGGTCACAGCACGAGTAC
CATGCCCGTGACGCTGGGTTACTGGGACATCCGCGGGCTGGCCCATGCCATCCGCCTGCTCCTG
GAGTACACAGACACCAGCTATGAGGAGAAGAGATACACCATGGGGGACGCTCCCGACTATGACA
GAAGCCAGTGGCTGAATGAGAAGTTCAAGCTGGGCCTGGACTTTCCCAATCTGCCCTACTTAAT
TGATGGGACTCACAAGCTCACCCAGAGCAACGCCATCCTGCGCTACATTGCCCGCAAGCACAGC
ATGTGTGGGGAGACAGAAGAGGAGAAGATTCGTGCGGACATTTTGGAGAACCAGGCTATGGACA
TCTCCAATCAGCTGGCCACAGTCTGCTACAGCCCAAACTTTGAGAAACTGAGGCCAGAGTACTT
GGAAGAACTCCCTGGGAAGATGAAGCTCTTCTCTGACTTCCTGGGGAAACGGCAGTGGTTTGTT
GGTAACAAGATCACCTATGTGGATTTCCTCGCTTATGATATACTTGACCTGCACCGTATATTTG
ACCCCAAGTGCCTGGAGGCGTTCCCTAACCTGAAGGACTTCATTTCTCGTTTTGAGGGCTTGAA
GAAGATCTCTGCCTACATGAAGTCCAGCCGCTTCCTCCCAACACCTTTATATACAAAGGTGGCC
ACATGGGGCAACAAGTAGGGCCTTGAAAGGGCAGGAGATGAGAGTGAGGAGCTCATTCTCTTCT
TGCTGCCCAGGGCCCAGCCTGACTATCCTGCCTGTTGGTGGCTGTGTCTGCTTTGAAGAGCAGG
GTCAGCACCCTCTCCTTGAAGCTTGGCACACCCCAGTCCCAACCCCAGGGGTGCCTGGAAGACC
AGTTTTGCGTGGTGGGTAACCCTGTGCCCCTGTGAGATCCCTGCCCCAGTCCTGTGTGATCTGA
GTAAAGTCCGAACCACACTTGCTCTATTTTTGTCTTTCTGTATCTGGCTGCACTTGACAGCTGG
TACTGCTACTTCCAAGGAACTGGGGGGTGGCTGGCTTCACGGAGGGAAGGAAGGGTTTTGAGAG
TTCCTGGTCCCGCGTTTGATACCCTTAGATTATGCAGCCCCGTGAGAGATCCTGTAGACAATAA
AAGATCTCTTTCTGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005388948	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000016576.1
	ENSCLAP00000016577.1
	ENSCLAP00000016578.1
	ENSCLAP00000016579
	ENSCLAP00000016579.1
	ENSCLAP00000016580.1
	ENSCLAP00000016582.1
	ENSCLAP00000016583.1
	ENSCLAP00000016584.1

RefSeq Acc Id:

XP_005388948 ⟸ XM_005388891

- UniProtKB:

A0A8C2VLL7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPVTLGYWDIRGLAHAIRLLLEYTDTSYEEKRYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI
DGTHKLTQSNAILRYIARKHSMCGETEEEKIRADILENQAMDISNQLATVCYSPNFEKLRPEYL
EELPGKMKLFSDFLGKRQWFVGNKITYVDFLAYDILDLHRIFDPKCLEAFPNLKDFISRFEGLK
KISAYMKSSRFLPTPLYTKVATWGNK

hide sequence

RefSeq Acc Id:

ENSCLAP00000016581 ⟸ ENSCLAT00000016745

RefSeq Acc Id:

ENSCLAP00000016580 ⟸ ENSCLAT00000016744

RefSeq Acc Id:

ENSCLAP00000016583 ⟸ ENSCLAT00000016747

RefSeq Acc Id:

ENSCLAP00000016582 ⟸ ENSCLAT00000016746

RefSeq Acc Id:

ENSCLAP00000016577 ⟸ ENSCLAT00000016741

RefSeq Acc Id:

ENSCLAP00000016576 ⟸ ENSCLAT00000016740

RefSeq Acc Id:

ENSCLAP00000016579 ⟸ ENSCLAT00000016743

RefSeq Acc Id:

ENSCLAP00000016578 ⟸ ENSCLAT00000016742

RefSeq Acc Id:

ENSCLAP00000016585 ⟸ ENSCLAT00000016749

RefSeq Acc Id:

ENSCLAP00000016584 ⟸ ENSCLAT00000016748

Protein Domains

GST C-terminal GST N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011395	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016740.1	UniProtKB/TrEMBL
	ENSCLAT00000016741.1	UniProtKB/TrEMBL
	ENSCLAT00000016742.1	UniProtKB/TrEMBL
	ENSCLAT00000016743	ENTREZGENE
	ENSCLAT00000016743.1	UniProtKB/TrEMBL
	ENSCLAT00000016744.1	UniProtKB/TrEMBL
	ENSCLAT00000016746.1	UniProtKB/TrEMBL
	ENSCLAT00000016747.1	UniProtKB/TrEMBL
	ENSCLAT00000016748.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1050.10	UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/TrEMBL
InterPro	Glutathione-S-Trfase_C-like	UniProtKB/TrEMBL
	Glutathione-S-Trfase_C_sf	UniProtKB/TrEMBL
	Glutathione_S-Trfase	UniProtKB/TrEMBL
	Glutathione_S-Trfase_N	UniProtKB/TrEMBL
	GST_C	UniProtKB/TrEMBL
	GST_mu	UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/TrEMBL
NCBI Gene	LOC102008976	ENTREZGENE
PANTHER	GLUTATHIONE S-TRANSFERASE	UniProtKB/TrEMBL
	GLUTATHIONE S-TRANSFERASE MU 1	UniProtKB/TrEMBL
	GLUTATHIONE S-TRANSFERASE MU 2	UniProtKB/TrEMBL
	GLUTATHIONE S-TRANSFERASE MU 4	UniProtKB/TrEMBL
Pfam	GST_C	UniProtKB/TrEMBL
	GST_N	UniProtKB/TrEMBL
PRINTS	GSTRNSFRASEM	UniProtKB/TrEMBL
PROSITE	GST_CTER	UniProtKB/TrEMBL
	GST_NTER	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47616	UniProtKB/TrEMBL
	SSF52833	UniProtKB/TrEMBL
UniProt	A0A8C2VJK4_CHILA	UniProtKB/TrEMBL
	A0A8C2VLL7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VLT9_CHILA	UniProtKB/TrEMBL
	A0A8C2VNL8_CHILA	UniProtKB/TrEMBL
	A0A8C2VPY7_CHILA	UniProtKB/TrEMBL
	A0A8C2VRT6_CHILA	UniProtKB/TrEMBL
	A0A8C2YQU7_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Gstm4	glutathione S-transferase mu 4	LOC102008976	glutathione S-transferase Mu 1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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