Ppia (peptidylprolyl isomerase A) - Rat Genome Database

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Gene: Ppia (peptidylprolyl isomerase A) Chinchilla lanigera
Analyze
Symbol: Ppia
Name: peptidylprolyl isomerase A
RGD ID: 8799221
Description: ENCODES a protein that exhibits cyclosporin A binding (ortholog); heparan sulfate binding (ortholog); integrin binding (ortholog); INVOLVED IN apoptotic process (ortholog); cell adhesion molecule production (ortholog); cellular response to oxidative stress (ortholog); ASSOCIATED WITH aggressive periodontitis (ortholog); atopic dermatitis (ortholog); Bell's palsy (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peptidyl-prolyl cis-trans isomerase A; peptidylprolyl isomerase A (cyclophilin A)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554567,381,923 - 7,383,203 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ppia
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554567,381,923 - 7,383,203 (-)NCBIChiLan1.0ChiLan1.0
PPIA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,796,681 - 44,803,117 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,796,680 - 44,824,564 (+)EnsemblGRCh38hg38GRCh38
GRCh37744,836,280 - 44,842,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,802,766 - 44,809,241 (+)NCBINCBI36Build 36hg18NCBI36
Build 34744,609,504 - 44,615,343NCBI
Celera744,935,095 - 44,941,571 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef744,721,292 - 44,727,768 (+)NCBIHuRef
CHM1_1744,840,586 - 44,847,069 (+)NCBICHM1_1
T2T-CHM13v2.0744,957,232 - 44,963,670 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,875,748 - 44,882,224 (+)NCBI
Ppia
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39116,365,867 - 6,369,817 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl116,365,443 - 6,369,817 (+)EnsemblGRCm39 Ensembl
GRCm38116,415,867 - 6,419,817 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl116,415,443 - 6,419,817 (+)EnsemblGRCm38mm10GRCm38
MGSCv37116,315,873 - 6,319,813 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36116,315,873 - 6,319,813 (+)NCBIMGSCv36mm8
Celera116,899,520 - 6,903,460 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.97NCBI
Ppia
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81485,491,223 - 85,496,884 (+)NCBIGRCr8
mRatBN7.21481,279,292 - 81,282,960 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,275,091 - 81,299,601 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,680,216 - 85,683,897 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,920,016 - 86,923,697 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01483,369,616 - 83,373,297 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,673,775 - 86,677,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,673,775 - 86,677,443 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01480,306,923 - 80,310,652 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,165,998 - 87,169,995 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11487,185,142 - 87,189,140 (+)NCBI
Celera1480,161,152 - 80,164,810 (+)NCBICelera
Cytogenetic Map14q21NCBI
PPIA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2649,708,848 - 49,714,864 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,034,551 - 98,039,602 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0745,510,450 - 45,515,448 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1745,578,764 - 45,583,516 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl745,578,765 - 45,605,545 (+)Ensemblpanpan1.1panPan2
LOC403581
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1780,937,433 - 80,938,175 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0781,027,063 - 81,027,805 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1780,741,873 - 80,742,615 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01764,379,529 - 64,380,271 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0781,058,591 - 81,059,333 (-)NCBIUU_Cfam_GSD_1.0
Ppia
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118100,457,966 - 100,461,621 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647819,669,727 - 19,673,355 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPIA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11850,563,130 - 50,566,857 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21855,286,994 - 55,290,557 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPIA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12113,876,099 - 13,883,546 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2113,876,099 - 13,883,462 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660628,652,515 - 8,658,073 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppia
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,447,554 - 7,450,641 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,447,554 - 7,450,707 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005396653   ⟹   XP_005396710
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554567,381,923 - 7,383,203 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396710 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009022
  ENSCLAP00000009022.1
Reference Protein Sequences
RefSeq Acc Id: XP_005396710   ⟸   XM_005396653
- UniProtKB: A0A8C2V1S1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
PPIase cyclophilin-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006301 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009150 ENTREZGENE
  ENSCLAT00000009150.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.100.10 UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
NCBI Gene LOC102016448 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A UniProtKB/TrEMBL
Pfam Pro_isomerase UniProtKB/TrEMBL
PIRSF Peptidylpro_ismrse UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50891 UniProtKB/TrEMBL
UniProt A0A8C2V1S1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ppia  peptidylprolyl isomerase A    peptidylprolyl isomerase A (cyclophilin A)  Symbol and/or name change 5135510 APPROVED
2015-08-25 Ppia  peptidylprolyl isomerase A (cyclophilin A)  LOC102016448  peptidyl-prolyl cis-trans isomerase A-like  Symbol and/or name change 5135510 APPROVED