Abcd2 (ATP binding cassette subfamily D member 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Abcd2 (ATP binding cassette subfamily D member 2) Chinchilla lanigera
Analyze
Symbol: Abcd2
Name: ATP binding cassette subfamily D member 2
RGD ID: 8798051
Description: ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); ATPase-coupled transmembrane transporter activity (ortholog); fatty acyl-CoA hydrolase activity (ortholog); INVOLVED IN fatty acid beta-oxidation (ortholog); myelin maintenance (ortholog); negative regulation of cytokine production involved in inflammatory response (ortholog); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylcarnitine translocase deficiency; fatty acid beta degradation pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); hypothyroidism (ortholog); FOUND IN peroxisomal membrane (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955505721,222 - 798,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955505717,800 - 769,702 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Abcd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955505721,222 - 798,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955505717,800 - 769,702 (+)NCBIChiLan1.0ChiLan1.0
ABCD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381239,531,025 - 39,619,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1239,550,033 - 39,619,803 (-)EnsemblGRCh38hg38GRCh38
GRCh371239,943,835 - 40,013,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361238,232,813 - 38,300,237 (-)NCBINCBI36Build 36hg18NCBI36
Build 341238,232,813 - 38,300,237NCBI
Celera1238,749,047 - 38,818,059 (-)NCBICelera
Cytogenetic Map12q12ENTREZGENE
HuRef1236,971,383 - 37,040,198 (-)NCBIHuRef
CHM1_11239,911,021 - 39,979,850 (-)NCBICHM1_1
T2T-CHM13v2.01239,480,907 - 39,601,214 (-)NCBIT2T-CHM13v2.0
Abcd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391591,029,874 - 91,076,013 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1591,030,074 - 91,076,002 (-)EnsemblGRCm39 Ensembl
GRCm381591,145,871 - 91,192,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1591,145,871 - 91,191,799 (-)EnsemblGRCm38mm10GRCm38
MGSCv371590,976,302 - 91,022,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361590,973,638 - 91,019,574 (-)NCBIMGSCv36mm8
Celera1593,253,156 - 93,299,066 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1546.0NCBI
Abcd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87124,142,597 - 124,191,202 (-)NCBIGRCr8
mRatBN7.27122,263,034 - 122,311,642 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7122,263,032 - 122,311,642 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7124,054,640 - 124,103,336 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07126,280,755 - 126,329,211 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07126,207,915 - 126,256,642 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07132,294,564 - 132,343,169 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7132,294,562 - 132,343,169 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07131,968,475 - 132,017,044 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47129,542,758 - 129,591,363 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17129,577,902 - 129,626,508 (-)NCBI
Celera7118,713,620 - 118,762,172 (-)NCBICelera
Cytogenetic Map7q35NCBI
ABCD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21054,525,947 - 54,601,622 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11254,522,683 - 54,598,358 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01249,082,122 - 49,158,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11249,941,914 - 50,011,140 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1249,941,914 - 50,011,140 (+)Ensemblpanpan1.1panPan2
ABCD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12714,015,093 - 14,084,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2714,015,091 - 14,163,312 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2732,351,661 - 32,426,133 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02714,182,734 - 14,251,081 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2714,187,982 - 14,251,183 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12713,992,155 - 14,060,013 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02714,030,140 - 14,098,038 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02732,500,349 - 32,568,488 (-)NCBIUU_Cfam_GSD_1.0
Abcd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494574,459,561 - 74,544,026 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366071,292,888 - 1,343,334 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366071,292,964 - 1,345,671 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl571,122,325 - 71,180,723 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1571,123,187 - 71,180,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2573,679,380 - 73,746,350 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11135,818,451 - 35,884,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037210,906,997 - 210,973,843 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624778847,879 - 909,727 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624778854,297 - 912,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000000826   ⟹   ENSCLAP00000000789
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955505721,222 - 769,702 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000000827   ⟹   ENSCLAP00000000790
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955505721,381 - 798,470 (+)Ensembl
RefSeq Acc Id: XM_005407101   ⟹   XP_005407158
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955505717,800 - 769,702 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407158 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000000789
  ENSCLAP00000000789.1
  ENSCLAP00000000790.1
Reference Protein Sequences
RefSeq Acc Id: XP_005407158   ⟸   XM_005407101
- UniProtKB: A0A8C2YIC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000000789   ⟸   ENSCLAT00000000826
RefSeq Acc Id: ENSCLAP00000000790   ⟸   ENSCLAT00000000827
Protein Domains
ABC transmembrane type-1   ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000619 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000000826 ENTREZGENE
  ENSCLAT00000000826.1 UniProtKB/TrEMBL
  ENSCLAT00000000827.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Abcd2 ENTREZGENE
PANTHER ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER UniProtKB/TrEMBL
  PTHR11384:SF24 UniProtKB/TrEMBL
Pfam ABC_membrane_2 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A8C2YIC1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Abcd2  ATP binding cassette subfamily D member 2    ATP-binding cassette, sub-family D (ALD), member 2  Symbol and/or name change 5135510 APPROVED