Kcnj10 (potassium inwardly rectifying channel subfamily J member 10) - Rat Genome Database

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Gene: Kcnj10 (potassium inwardly rectifying channel subfamily J member 10) Chinchilla lanigera
Analyze
Symbol: Kcnj10
Name: potassium inwardly rectifying channel subfamily J member 10
RGD ID: 8782144
Description: ENCODES a protein that exhibits identical protein binding (ortholog); inward rectifier potassium channel activity (ortholog); potassium channel activity (ortholog); INVOLVED IN adult walking behavior (ortholog); cellular response to potassium ion (ortholog); central nervous system myelination (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); amyotrophic lateral sclerosis (ortholog); autistic disorder (ortholog); FOUND IN apical plasma membrane (ortholog); astrocyte projection (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-sensitive inward rectifier potassium channel 10; potassium channel, inwardly rectifying subfamily J, member 10; potassium inwardly-rectifying channel, subfamily J, member 10; potassium voltage-gated channel subfamily J member 10
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,828,525 - 11,860,365 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546811,828,525 - 11,860,365 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnj10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546811,828,525 - 11,860,365 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546811,828,525 - 11,860,365 (-)NCBIChiLan1.0ChiLan1.0
KCNJ10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381160,037,467 - 160,070,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1159,998,651 - 160,070,160 (-)EnsemblGRCh38hg38GRCh38
GRCh371160,007,257 - 160,039,950 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361158,274,657 - 158,306,585 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,821,107 - 156,853,111NCBI
Celera1133,075,700 - 133,108,518 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,363,984 - 131,396,837 (-)NCBIHuRef
CHM1_11161,402,581 - 161,435,439 (-)NCBICHM1_1
T2T-CHM13v2.01159,174,545 - 159,207,239 (-)NCBIT2T-CHM13v2.0
Kcnj10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,168,777 - 172,201,652 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,168,777 - 172,201,652 (+)EnsemblGRCm39 Ensembl
GRCm381172,341,210 - 172,374,085 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,341,210 - 172,374,085 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,271,341 - 174,304,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,630,700 - 173,663,577 (+)NCBIMGSCv36mm8
MGSCv361174,177,885 - 174,210,760 (+)NCBIMGSCv36mm8
Celera1175,194,717 - 175,227,512 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.69NCBI
Kcnj10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,334,510 - 87,367,747 (+)NCBIGRCr8
mRatBN7.21384,802,026 - 84,835,383 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1384,802,009 - 84,835,461 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,305,458 - 87,334,963 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01388,705,734 - 88,735,235 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01385,890,102 - 85,919,618 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01390,722,945 - 90,753,338 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1390,723,092 - 90,752,581 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,245,046 - 95,274,535 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,341,102 - 88,370,591 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11388,529,985 - 88,559,475 (+)NCBI
Celera1384,412,223 - 84,441,711 (+)NCBICelera
Cytogenetic Map13q24NCBI
KCNJ10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,781,939 - 89,814,731 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,521,944 - 89,554,744 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,391,321 - 135,424,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11139,312,371 - 139,345,145 (-)NCBIpanpan1.1PanPan1.1panPan2
KCNJ10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,114,718 - 22,143,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,130,508 - 22,140,813 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,189,839 - 22,218,736 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,234,321 - 22,263,231 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,233,505 - 22,263,228 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,138,483 - 22,167,351 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,534,821 - 22,563,698 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,944,114 - 22,972,999 (+)NCBIUU_Cfam_GSD_1.0
Kcnj10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050586,165,284 - 6,198,606 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740555,998 - 586,353 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936740555,948 - 589,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,422,025 - 90,457,406 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,421,956 - 90,457,406 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,438,760 - 98,443,881 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNJ10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1203,873,915 - 3,907,587 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl203,902,513 - 3,903,652 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660382,932,155 - 2,964,080 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,180,834 - 1,212,456 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247941,180,822 - 1,211,781 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000025453   ⟹   ENSCLAP00000025207
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546811,828,525 - 11,860,365 (-)Ensembl
RefSeq Acc Id: XM_005400189   ⟹   XP_005400246
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546811,828,525 - 11,860,365 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400246 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025207
  ENSCLAP00000025207.1
Reference Protein Sequences
RefSeq Acc Id: XP_005400246   ⟸   XM_005400189
- UniProtKB: A0A8C2YUY9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000025207   ⟸   ENSCLAT00000025453
Protein Domains
Inward rectifier potassium channel C-terminal   Potassium channel inwardly rectifying transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017311 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000025453 ENTREZGENE
  ENSCLAT00000025453.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir1.2 UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/TrEMBL
  Kir_TM UniProtKB/TrEMBL
NCBI Gene Kcnj10 ENTREZGENE
PANTHER PTHR11767 UniProtKB/TrEMBL
  PTHR11767:SF21 UniProtKB/TrEMBL
Pfam IRK UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
PIRSF GIRK_kir UniProtKB/TrEMBL
PRINTS KIR12CHANNEL UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C2YUY9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 Kcnj10  potassium inwardly rectifying channel subfamily J member 10  Kcnj10  potassium voltage-gated channel subfamily J member 10  Symbol and/or name change 5135510 APPROVED
2016-08-03 Kcnj10  potassium voltage-gated channel subfamily J member 10    potassium channel, inwardly rectifying subfamily J, member 10  Symbol and/or name change 5135510 APPROVED
2015-08-25 Kcnj10  potassium channel, inwardly rectifying subfamily J, member 10    potassium inwardly-rectifying channel, subfamily J, member 10  Symbol and/or name change 5135510 APPROVED