Usp7 (ubiquitin specific peptidase 7) - Rat Genome Database

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Gene: Usp7 (ubiquitin specific peptidase 7) Chinchilla lanigera
Analyze
Symbol: Usp7
Name: ubiquitin specific peptidase 7
RGD ID: 8775227
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN DNA alkylation repair (ortholog); monoubiquitinated protein deubiquitination (ortholog); negative regulation of gene expression via chromosomal CpG island methylation (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 1C (ortholog); GABA aminotransferase deficiency (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7 (herpes virus-associated)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554429,315,225 - 9,356,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554429,316,022 - 9,355,751 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Usp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554429,315,225 - 9,356,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554429,316,022 - 9,355,751 (+)NCBIChiLan1.0ChiLan1.0
USP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38168,892,097 - 8,963,906 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl168,892,097 - 8,975,328 (-)EnsemblGRCh38hg38GRCh38
GRCh37168,985,954 - 9,057,763 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,893,452 - 8,964,842 (-)NCBINCBI36Build 36hg18NCBI36
Build 34168,894,850 - 8,964,842NCBI
Celera169,152,724 - 9,223,882 (-)NCBICelera
Cytogenetic Map16p13.2NCBI
HuRef168,907,081 - 8,945,418 (-)NCBIHuRef
CHM1_1168,985,936 - 9,057,340 (-)NCBICHM1_1
T2T-CHM13v2.0168,924,836 - 8,996,578 (-)NCBIT2T-CHM13v2.0
Usp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39168,506,586 - 8,574,931 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl168,507,459 - 8,610,172 (-)EnsemblGRCm39 Ensembl
GRCm38168,688,722 - 8,757,067 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl168,689,595 - 8,792,308 (-)EnsemblGRCm38mm10GRCm38
MGSCv37168,688,815 - 8,738,435 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36168,606,101 - 8,653,606 (-)NCBIMGSCv36mm8
Celera169,334,440 - 9,362,384 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map164.28NCBI
Usp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8107,335,508 - 7,432,018 (+)NCBIGRCr8
mRatBN7.2106,880,684 - 6,925,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl106,828,795 - 6,925,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1011,588,325 - 11,631,578 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01011,084,682 - 11,128,048 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0106,735,783 - 6,779,154 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0106,930,462 - 7,019,910 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl106,975,244 - 7,018,930 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0105,752,834 - 5,822,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4106,917,612 - 6,963,452 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1106,917,611 - 6,963,451 (+)NCBI
Celera105,876,459 - 5,919,649 (+)NCBICelera
Cytogenetic Map10q12NCBI
USP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,431,901 - 9,501,001 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11613,210,502 - 13,278,888 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0167,825,332 - 7,895,095 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1169,065,366 - 9,106,406 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl169,065,858 - 9,106,146 (-)Ensemblpanpan1.1panPan2
USP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1633,277,328 - 33,315,601 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl633,277,444 - 33,314,491 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha634,641,327 - 34,706,509 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0633,449,047 - 33,514,314 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl633,448,218 - 33,514,312 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1633,251,796 - 33,316,926 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0633,121,375 - 33,186,820 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0633,570,486 - 33,608,545 (+)NCBIUU_Cfam_GSD_1.0
Usp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344109,848,236 - 109,882,862 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365307,694,379 - 7,724,684 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365307,693,681 - 7,724,215 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl333,775,829 - 33,810,465 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1333,754,357 - 33,810,480 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2334,686,115 - 34,742,973 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.158,470,137 - 8,540,736 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl58,469,230 - 8,540,770 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606821,677,314 - 21,749,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248246,276,354 - 6,338,227 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248246,277,111 - 6,338,051 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018900   ⟹   ENSCLAP00000018715
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554429,315,225 - 9,356,393 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000018901   ⟹   ENSCLAP00000018716
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554429,320,749 - 9,354,567 (+)Ensembl
RefSeq Acc Id: XM_005391205   ⟹   XP_005391262
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554429,316,022 - 9,355,751 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005391206   ⟹   XP_005391263
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554429,316,928 - 9,355,751 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005391207   ⟹   XP_005391264
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554429,316,928 - 9,355,751 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013517899   ⟹   XP_013373353
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554429,316,928 - 9,355,751 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391262 (Get FASTA)   NCBI Sequence Viewer  
  XP_005391263 (Get FASTA)   NCBI Sequence Viewer  
  XP_005391264 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373353 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018715
  ENSCLAP00000018715.1
  ENSCLAP00000018716.1
Reference Protein Sequences
RefSeq Acc Id: XP_005391262   ⟸   XM_005391205
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VPR2 (UniProtKB/TrEMBL),   A0A8C2VWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005391264   ⟸   XM_005391207
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005391263   ⟸   XM_005391206
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373353   ⟸   XM_013517899
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VWY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018715   ⟸   ENSCLAT00000018900
RefSeq Acc Id: ENSCLAP00000018716   ⟸   ENSCLAT00000018901
Protein Domains
MATH   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012834 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018900 ENTREZGENE
  ENSCLAT00000018900.1 UniProtKB/TrEMBL
  ENSCLAT00000018901.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro MATH/TRAF_dom UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
  USP7_ICP0-binding_dom UniProtKB/TrEMBL
  USP_C UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
NCBI Gene Usp7 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 UniProtKB/TrEMBL
Pfam MATH UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  USP7_C2 UniProtKB/TrEMBL
  USP7_ICP0_bdg UniProtKB/TrEMBL
PROSITE MATH UniProtKB/TrEMBL
  USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
SMART MATH UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/TrEMBL
UniProt A0A8C2VPR2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VWY0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Usp7  ubiquitin specific peptidase 7    ubiquitin specific peptidase 7 (herpes virus-associated)  Symbol and/or name change 5135510 APPROVED