Kcnb1 (potassium voltage-gated channel subfamily B member 1) - Rat Genome Database

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Gene: Kcnb1 (potassium voltage-gated channel subfamily B member 1) Chinchilla lanigera
Analyze
Symbol: Kcnb1
Name: potassium voltage-gated channel subfamily B member 1
RGD ID: 8768251
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); outward rectifier potassium channel activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN action potential (ortholog); cellular response to calcium ion (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 26 (ortholog); Diaphragmatic Hernia (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel, voltage gated Shab related subfamily B, member 1; potassium voltage-gated channel, Shab-related subfamily, member 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554458,680,965 - 8,774,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554458,680,979 - 8,779,662 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554458,680,965 - 8,774,110 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554458,680,979 - 8,779,662 (+)NCBIChiLan1.0ChiLan1.0
KCNB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382049,363,877 - 49,483,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2049,293,394 - 49,484,297 (-)EnsemblGRCh38hg38GRCh38
GRCh372047,980,414 - 48,099,205 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362047,421,912 - 47,532,588 (-)NCBINCBI36Build 36hg18NCBI36
Build 342047,421,911 - 47,532,588NCBI
Celera2044,693,122 - 44,803,814 (-)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2044,737,067 - 44,847,754 (-)NCBIHuRef
CHM1_12047,892,894 - 48,003,606 (-)NCBICHM1_1
T2T-CHM13v2.02051,133,489 - 51,253,649 (-)NCBIT2T-CHM13v2.0
Kcnb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392166,937,889 - 167,032,088 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2166,937,889 - 167,032,075 (-)EnsemblGRCm39 Ensembl
GRCm382167,095,969 - 167,190,072 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2167,095,969 - 167,190,155 (-)EnsemblGRCm38mm10GRCm38
MGSCv372166,928,878 - 167,014,299 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362166,794,583 - 166,880,004 (-)NCBIMGSCv36mm8
Celera2173,043,474 - 173,128,977 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map287.22NCBI
Kcnb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83176,239,285 - 176,332,408 (-)NCBIGRCr8
mRatBN7.23155,820,255 - 155,913,383 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3155,822,963 - 155,916,194 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3159,621,853 - 159,714,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03168,120,826 - 168,213,919 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03165,862,536 - 165,955,629 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03163,850,785 - 163,935,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3163,850,785 - 163,935,617 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,010,756 - 170,094,507 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43158,250,001 - 158,345,927 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13158,156,036 - 158,248,459 (-)NCBI
Celera3154,408,682 - 154,493,576 (-)NCBICelera
RH 3.4 Map31476.0RGD
Cytogenetic Map3q42NCBI
KCNB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22155,039,862 - 55,225,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12055,032,968 - 55,218,159 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02045,636,371 - 45,821,536 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12046,761,428 - 46,885,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2046,776,274 - 46,885,521 (-)Ensemblpanpan1.1panPan2
KCNB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12436,016,800 - 36,118,873 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2436,025,472 - 36,117,934 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2435,259,329 - 35,359,756 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02436,721,821 - 36,822,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2436,729,609 - 36,823,404 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12435,962,506 - 36,063,208 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02436,096,677 - 36,197,268 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02436,638,300 - 36,739,394 (-)NCBIUU_Cfam_GSD_1.0
Kcnb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640189,373,582 - 189,447,939 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365144,827,127 - 4,900,707 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365144,827,156 - 4,902,271 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1751,039,987 - 51,142,644 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11751,032,163 - 51,152,566 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21757,354,303 - 57,464,782 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1214,510,176 - 14,623,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl214,510,464 - 14,619,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605062,995,224 - 63,111,025 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247905,902,077 - 6,003,591 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247905,901,809 - 6,007,847 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008215   ⟹   ENSCLAP00000008091
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554458,680,965 - 8,774,110 (+)Ensembl
RefSeq Acc Id: XM_005392330   ⟹   XP_005392387
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554458,680,979 - 8,779,662 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005392387 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008091
  ENSCLAP00000008091.1
Reference Protein Sequences
RefSeq Acc Id: XP_005392387   ⟸   XM_005392330
- UniProtKB: A0A8C2V609 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000008091   ⟸   ENSCLAT00000008215
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005669 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008215 ENTREZGENE
  ENSCLAT00000008215.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv2 UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv2.1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcnb1 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY B MEMBER 1 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  Kv2channel UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KV21CHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
  SHABCHANNEL UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C2V609 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Kcnb1  potassium voltage-gated channel subfamily B member 1    potassium channel, voltage gated Shab related subfamily B, member 1  Symbol and/or name change 5135510 APPROVED
2015-08-25 Kcnb1  potassium channel, voltage gated Shab related subfamily B, member 1    potassium voltage-gated channel, Shab-related subfamily, member 1  Symbol and/or name change 5135510 APPROVED