Kcnc2 (potassium voltage-gated channel subfamily C member 2) - Rat Genome Database

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Gene: Kcnc2 (potassium voltage-gated channel subfamily C member 2) Chinchilla lanigera
Analyze
Symbol: Kcnc2
Name: potassium voltage-gated channel subfamily C member 2
RGD ID: 8767252
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); transmembrane transporter binding (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN action potential (ortholog); cellular response to ammonium ion (ortholog); cellular response to nitric oxide (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 103 (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN apical plasma membrane (ortholog); axolemma (ortholog); axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel, voltage gated Shaw related subfamily C, member 2; potassium voltage-gated channel, Shaw-related subfamily, member 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540514,422,396 - 14,600,341 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540514,420,447 - 14,599,780 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540514,422,396 - 14,600,341 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540514,420,447 - 14,599,780 (-)NCBIChiLan1.0ChiLan1.0
KCNC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381275,040,078 - 75,209,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1275,040,077 - 75,209,839 (-)EnsemblGRCh38hg38GRCh38
GRCh371275,433,858 - 75,603,619 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361273,720,163 - 73,889,778 (-)NCBINCBI36Build 36hg18NCBI36
Build 341273,720,162 - 73,889,778NCBI
Celera1275,101,336 - 75,270,876 (-)NCBICelera
Cytogenetic Map12q21.1NCBI
HuRef1272,483,472 - 72,653,079 (-)NCBIHuRef
CHM1_11275,399,235 - 75,568,820 (-)NCBICHM1_1
T2T-CHM13v2.01275,014,738 - 75,184,480 (-)NCBIT2T-CHM13v2.0
Kcnc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910112,105,803 - 112,302,209 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10112,107,026 - 112,302,929 (+)EnsemblGRCm39 Ensembl
GRCm3810112,269,898 - 112,466,304 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10112,271,121 - 112,467,024 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710111,708,179 - 111,903,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610111,675,233 - 111,870,414 (+)NCBIMGSCv36mm8
Celera10114,210,354 - 114,400,944 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1060.3NCBI
Kcnc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8749,586,274 - 49,770,212 (+)NCBIGRCr8
mRatBN7.2747,700,035 - 47,883,979 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl747,700,288 - 47,883,968 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx749,609,550 - 49,792,283 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0751,812,632 - 51,995,385 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0751,590,463 - 51,773,199 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0754,978,453 - 55,159,362 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl754,980,120 - 55,159,351 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0754,998,077 - 55,177,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4751,326,602 - 51,487,958 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1751,347,043 - 51,508,400 (+)NCBI
Celera744,495,328 - 44,675,986 (+)NCBICelera
Cytogenetic Map7q22NCBI
KCNC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21083,082,905 - 83,251,756 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11283,079,301 - 83,248,152 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01272,566,924 - 72,736,270 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11275,419,465 - 75,588,535 (-)NCBIpanpan1.1PanPan1.1panPan2
KCNC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11015,599,428 - 15,822,579 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1015,643,962 - 15,818,097 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1015,541,357 - 15,767,201 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01015,785,996 - 16,011,988 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1015,789,212 - 16,007,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11015,595,746 - 15,821,564 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01015,848,484 - 16,075,795 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01015,974,622 - 16,200,463 (-)NCBIUU_Cfam_GSD_1.0
Kcnc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494542,033,763 - 42,220,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365683,511,244 - 3,694,781 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365683,508,212 - 3,694,459 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl538,326,414 - 38,533,110 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1538,326,408 - 38,535,826 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2541,759,389 - 41,781,754 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11170,603,034 - 70,770,625 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1170,603,003 - 70,768,859 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037174,772,549 - 174,940,514 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475022,807,370 - 22,996,753 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475022,807,234 - 22,996,614 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000013574   ⟹   ENSCLAP00000013421
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540514,422,396 - 14,600,341 (-)Ensembl
RefSeq Acc Id: XM_013517673   ⟹   XP_013373127
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540514,420,447 - 14,599,780 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013373127 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013421
  ENSCLAP00000013421.1
RefSeq Acc Id: XP_013373127   ⟸   XM_013517673
- UniProtKB: A0A8C2VDV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000013421   ⟸   ENSCLAT00000013574
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009275 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013574 ENTREZGENE
  ENSCLAT00000013574.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv3 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcnc2 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
  SHAWCHANNEL UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C2VDV7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Kcnc2  potassium voltage-gated channel subfamily C member 2    potassium channel, voltage gated Shaw related subfamily C, member 2  Symbol and/or name change 5135510 APPROVED
2015-08-25 Kcnc2  potassium channel, voltage gated Shaw related subfamily C, member 2    potassium voltage-gated channel, Shaw-related subfamily, member 2  Symbol and/or name change 5135510 APPROVED