Adcy2 (adenylate cyclase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Adcy2 (adenylate cyclase 2) Chinchilla lanigera
Analyze
Symbol: Adcy2
Name: adenylate cyclase 2
RGD ID: 8759254
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); adenylate cyclase binding (ortholog); G-protein beta/gamma-subunit complex binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); cAMP biosynthetic process (ortholog); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; endothelin signaling pathway; ASSOCIATED WITH asthma (ortholog); bipolar disorder (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate cyclase 2 (brain); adenylate cyclase type 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555045,004,903 - 5,376,328 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555044,990,634 - 5,376,990 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adcy2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555045,004,903 - 5,376,328 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555044,990,634 - 5,376,990 (+)NCBIChiLan1.0ChiLan1.0
ADCY2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3857,396,138 - 7,830,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl57,396,138 - 7,830,081 (+)EnsemblGRCh38hg38GRCh38
GRCh3757,396,251 - 7,830,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3657,449,343 - 7,883,194 (+)NCBINCBI36Build 36hg18NCBI36
Build 3457,449,344 - 7,883,194NCBI
Celera57,439,102 - 7,871,262 (+)NCBICelera
Cytogenetic Map5p15.31NCBI
HuRef57,725,521 - 7,811,956 (+)NCBIHuRef
HuRef57,378,757 - 7,709,814 (+)NCBIHuRef
CHM1_157,396,258 - 7,830,278 (+)NCBICHM1_1
T2T-CHM13v2.057,334,987 - 7,769,222 (+)NCBIT2T-CHM13v2.0
Adcy2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391368,768,162 - 69,147,719 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1368,768,162 - 69,147,660 (-)EnsemblGRCm39 Ensembl
GRCm381368,620,043 - 68,999,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1368,620,043 - 68,999,541 (-)EnsemblGRCm38mm10GRCm38
MGSCv371368,758,920 - 69,138,419 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361369,087,431 - 69,466,658 (-)NCBIMGSCv36mm8
Celera1370,976,336 - 71,362,097 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.55NCBI
Adcy2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8136,204,054 - 36,650,645 (+)NCBIGRCr8
mRatBN7.2134,375,639 - 34,822,252 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl134,375,895 - 34,822,236 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx134,237,007 - 34,683,571 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0140,227,844 - 40,674,423 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0134,402,593 - 34,849,151 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0137,043,071 - 37,698,390 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl137,507,276 - 37,698,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0139,075,253 - 39,080,014 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0138,434,800 - 39,001,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4174,543,466 - 5,040,433 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera132,960,049 - 33,391,637 (+)NCBICelera
Cytogenetic Map1p11NCBI
ADCY2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v247,647,272 - 8,082,790 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan155,800,880 - 6,236,399 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v057,718,581 - 8,154,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.157,540,762 - 7,975,853 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl57,540,790 - 7,975,853 (+)Ensemblpanpan1.1panPan2
ADCY2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1346,139,931 - 6,527,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl346,140,276 - 6,527,677 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3410,648,056 - 11,035,866 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0346,045,474 - 6,434,089 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl346,045,476 - 6,434,095 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1346,095,233 - 6,483,250 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0346,075,965 - 6,464,063 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0346,288,901 - 6,677,489 (-)NCBIUU_Cfam_GSD_1.0
Adcy2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213239,063,958 - 239,560,683 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493664347,837 - 339,007 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493664347,830 - 338,891 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1674,305,736 - 74,524,295 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11674,305,729 - 74,729,999 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21680,359,861 - 80,498,999 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.146,989,077 - 7,415,282 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl46,989,169 - 7,414,617 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606421,200,037 - 21,628,571 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247515,004,263 - 5,413,994 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247515,004,186 - 5,409,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005772   ⟹   ENSCLAP00000005671
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555045,004,903 - 5,376,328 (+)Ensembl
RefSeq Acc Id: XM_005407072   ⟹   XP_005407129
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555044,990,634 - 5,376,990 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407129 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005671
  ENSCLAP00000005671.1
Reference Protein Sequences
RefSeq Acc Id: XP_005407129   ⟸   XM_005407072
- UniProtKB: A0A8C2UTQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005671   ⟸   ENSCLAT00000005772
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004022 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005772 ENTREZGENE
  ENSCLAT00000005772.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1230 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  AC_N UniProtKB/TrEMBL
  Adcy UniProtKB/TrEMBL
  Adcy_conserved_dom UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Adcy2 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
  ADENYLATE CYCLASE TYPE 2 UniProtKB/TrEMBL
Pfam AC_N UniProtKB/TrEMBL
  DUF1053 UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/TrEMBL
PIRSF Ade_cyc UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF55073 UniProtKB/TrEMBL
UniProt A0A8C2UTQ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Adcy2  adenylate cyclase 2    adenylate cyclase 2 (brain)  Symbol and/or name change 5135510 APPROVED