Hpse2 (heparanase 2 (inactive)) - Rat Genome Database

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Gene: Hpse2 (heparanase 2 (inactive)) Chinchilla lanigera
Analyze
Symbol: Hpse2
Name: heparanase 2 (inactive)
RGD ID: 8745555
Description: ENCODES a protein that exhibits heparan sulfate proteoglycan binding (ortholog); heparanase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); extracellular matrix organization (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH CAKUT (ortholog); genetic disease (ortholog); urofacial syndrome (ortholog); FOUND IN extracellular matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive heparanase-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555074,445,772 - 5,205,957 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555074,442,677 - 5,205,976 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hpse2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555074,445,772 - 5,205,957 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555074,442,677 - 5,205,976 (-)NCBIChiLan1.0ChiLan1.0
HPSE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381098,457,077 - 99,315,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1098,457,077 - 99,235,862 (-)EnsemblGRCh38hg38GRCh38
GRCh3710100,216,834 - 100,995,632 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610100,208,867 - 100,985,609 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410100,208,864 - 100,985,609NCBI
Celera1093,953,460 - 94,732,450 (-)NCBICelera
Cytogenetic Map10q24.2NCBI
HuRef1094,130,091 - 94,622,164 (-)NCBIHuRef
HuRef1093,841,617 - 94,106,699 (-)NCBIHuRef
CHM1_110100,498,701 - 101,277,572 (-)NCBICHM1_1
T2T-CHM13v2.01099,337,053 - 100,197,827 (-)NCBIT2T-CHM13v2.0
Hpse2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391942,774,980 - 43,376,913 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1942,774,978 - 43,376,794 (-)EnsemblGRCm39 Ensembl
GRCm381942,786,541 - 43,388,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1942,786,539 - 43,388,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv371942,863,085 - 43,462,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361942,841,906 - 43,441,622 (-)NCBIMGSCv36mm8
MGSCv361942,676,998 - 43,277,483 (-)NCBIMGSCv36mm8
Celera1943,584,218 - 44,179,795 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1936.57NCBI
Hpse2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81251,532,149 - 252,231,316 (-)NCBIGRCr8
mRatBN7.21241,582,904 - 242,284,348 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1241,583,187 - 242,246,118 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1249,730,681 - 250,396,023 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01256,427,848 - 257,093,195 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01249,080,851 - 249,746,182 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01262,020,903 - 263,138,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01270,576,436 - 270,580,047 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01269,475,568 - 270,128,189 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41247,458,939 - 248,100,231 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11247,958,907 - 247,971,603 (+)NCBI
Celera1237,417,175 - 238,067,548 (-)NCBICelera
Cytogenetic Map1q54NCBI
HPSE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28110,363,078 - 111,143,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110110,368,396 - 111,148,445 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01095,071,571 - 95,851,896 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11098,566,705 - 99,344,205 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1098,592,019 - 99,344,132 (-)Ensemblpanpan1.1panPan2
HPSE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12811,584,440 - 12,215,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2811,585,807 - 12,215,614 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2811,766,981 - 12,399,809 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02811,909,883 - 12,161,577 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2811,912,217 - 12,683,674 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12811,593,608 - 12,230,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02811,630,471 - 12,261,439 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02811,770,213 - 12,402,804 (-)NCBIUU_Cfam_GSD_1.0
Hpse2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721334,735,574 - 35,362,965 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936636774,778 - 1,399,702 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936636774,705 - 1,402,009 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HPSE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14109,764,170 - 110,469,141 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114109,764,511 - 110,469,064 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214119,262,145 - 119,752,959 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103216367
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1991,616,277 - 92,346,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604852,670,244 - 52,785,944 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hpse2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473710,058,787 - 10,976,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473710,055,408 - 10,976,525 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005407665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01065648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01065667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDK01049880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000002797   ⟹   ENSCLAP00000002741
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555074,445,772 - 5,205,957 (-)Ensembl
RefSeq Acc Id: XM_005407665   ⟹   XP_005407722
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555074,442,677 - 5,205,976 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002741
  ENSCLAP00000002741.1
Reference Protein Sequences
RefSeq Acc Id: XP_005407722   ⟸   XM_005407665
- UniProtKB: A0A8C2URP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002741   ⟸   ENSCLAT00000002797


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001979 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002797 ENTREZGENE
  ENSCLAT00000002797.1 UniProtKB/TrEMBL
Gene3D-CATH Glycosidases UniProtKB/TrEMBL
InterPro Glyco_hydro_79 UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
NCBI Gene Hpse2 ENTREZGENE
PANTHER HEPARANASE UniProtKB/TrEMBL
  INACTIVE HEPARANASE-2 UniProtKB/TrEMBL
Pfam Glyco_hydro_79n UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
UniProt A0A8C2URP0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Hpse2  heparanase 2 (inactive)    heparanase 2  Symbol and/or name change 5135510 APPROVED