Man1c1 (mannosidase alpha class 1C member 1) - Rat Genome Database

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Gene: Man1c1 (mannosidase alpha class 1C member 1) Chinchilla lanigera
Analyze
Symbol: Man1c1
Name: mannosidase alpha class 1C member 1
RGD ID: 8732891
Description: ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); retinitis pigmentosa 59 (ortholog); rigid spine muscular dystrophy 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mannosidase, alpha, class 1C, member 1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,146,633 - 5,279,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,147,247 - 5,281,229 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Man1c1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,146,633 - 5,279,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,147,247 - 5,281,229 (+)NCBIChiLan1.0ChiLan1.0
MAN1C1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38125,616,791 - 25,784,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl125,616,791 - 25,784,450 (+)EnsemblGRCh38hg38GRCh38
GRCh37125,943,282 - 26,110,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,816,546 - 25,983,845 (+)NCBINCBI36Build 36hg18NCBI36
Build 34125,628,104 - 25,795,084NCBI
Celera124,340,032 - 24,507,337 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,197,844 - 24,350,677 (+)NCBIHuRef
HuRef124,360,764 - 24,367,428 (+)NCBIHuRef
CHM1_1126,057,325 - 26,224,752 (+)NCBICHM1_1
T2T-CHM13v2.0125,454,132 - 25,621,930 (+)NCBIT2T-CHM13v2.0
Man1c1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,289,001 - 134,432,987 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4134,289,001 - 134,431,601 (-)EnsemblGRCm39 Ensembl
GRCm384134,561,690 - 134,704,290 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,561,690 - 134,704,290 (-)EnsemblGRCm38mm10GRCm38
MGSCv374134,117,605 - 134,260,205 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,833,766 - 133,976,366 (-)NCBIMGSCv36mm8
Celera4132,744,361 - 132,888,173 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map466.88NCBI
Man1c1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85152,057,839 - 152,197,737 (-)NCBIGRCr8
mRatBN7.25146,774,282 - 146,913,257 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,775,842 - 146,913,421 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,476,205 - 149,614,242 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05151,246,417 - 151,385,391 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05151,232,448 - 151,370,486 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,775,031 - 152,920,130 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,774,855 - 152,920,343 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,559,978 - 156,703,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,318,031 - 153,459,786 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15153,329,958 - 153,470,077 (-)NCBI
Celera5145,189,372 - 145,326,733 (-)NCBICelera
Cytogenetic Map5q36NCBI
MAN1C1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21201,089,581 - 201,255,379 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11200,185,745 - 200,354,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,877,014 - 25,044,891 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1125,943,770 - 26,112,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl125,943,949 - 26,110,456 (+)Ensemblpanpan1.1panPan2
MAN1C1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,164,483 - 74,304,059 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,165,127 - 74,304,044 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,729,721 - 70,878,335 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,716,697 - 74,865,309 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,721,600 - 74,865,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,539,915 - 71,688,722 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,546,929 - 72,695,479 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,551,081 - 73,699,727 (-)NCBIUU_Cfam_GSD_1.0
Man1c1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,471,291 - 44,542,384 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647410,297,853 - 10,367,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAN1C1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,089,072 - 83,228,008 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,089,942 - 83,228,648 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,660,476 - 76,797,566 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAN1C1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,989,694 - 107,158,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,987,360 - 107,158,437 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,247,179 - 9,425,964 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Man1c1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247649,745,011 - 9,879,204 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247649,745,726 - 9,876,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000019597   ⟹   ENSCLAP00000019405
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554525,146,633 - 5,279,136 (+)Ensembl
RefSeq Acc Id: XM_005394825   ⟹   XP_005394882
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554525,147,247 - 5,281,229 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394882 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019405
  ENSCLAP00000019405.1
RefSeq Acc Id: XP_005394882   ⟸   XM_005394825
- UniProtKB: A0A8C2VWG1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000019405   ⟸   ENSCLAT00000019597


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013310 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019597 ENTREZGENE
  ENSCLAT00000019597.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/TrEMBL
InterPro 6hp_glycosidase-like_sf UniProtKB/TrEMBL
  Glyco_hydro_47 UniProtKB/TrEMBL
  Glycosyl_Hydrolase_47 UniProtKB/TrEMBL
  Seven-hairpin_glycosidases UniProtKB/TrEMBL
NCBI Gene Man1c1 ENTREZGENE
PANTHER MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IC UniProtKB/TrEMBL
  MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED UniProtKB/TrEMBL
Pfam Glyco_hydro_47 UniProtKB/TrEMBL
PRINTS GLYHDRLASE47 UniProtKB/TrEMBL
Superfamily-SCOP SSF48225 UniProtKB/TrEMBL
UniProt A0A8C2VWG1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Man1c1  mannosidase alpha class 1C member 1    mannosidase, alpha, class 1C, member 1  Symbol and/or name change 5135510 APPROVED