Rph3a (rabphilin 3A) - Rat Genome Database

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Gene: Rph3a (rabphilin 3A) Chinchilla lanigera
Analyze
Symbol: Rph3a
Name: rabphilin 3A
RGD ID: 8716639
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); inositol 1,4,5 trisphosphate binding (ortholog); INVOLVED IN dendritic spine organization (ortholog); spontaneous neurotransmitter secretion (ortholog); synaptic vesicle priming (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); FOUND IN cholinergic synapse (ortholog); dendritic spine (ortholog); extrinsic component of membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rabphilin 3A homolog; rabphilin-3A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,225,845 - 9,312,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,190,137 - 9,312,596 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Rph3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554829,225,845 - 9,312,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554829,190,137 - 9,312,596 (+)NCBIChiLan1.0ChiLan1.0
RPH3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812112,575,236 - 112,898,881 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12112,570,380 - 112,898,881 (+)EnsemblGRCh38hg38GRCh38
GRCh3712113,013,040 - 113,336,686 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612111,714,125 - 111,819,631 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412111,692,461 - 111,797,964NCBI
Celera12112,856,609 - 112,963,778 (+)NCBICelera
Cytogenetic Map12q24.13NCBI
HuRef12110,241,984 - 110,349,225 (+)NCBIHuRef
CHM1_112113,197,984 - 113,305,112 (+)NCBICHM1_1
T2T-CHM13v2.012112,552,138 - 112,875,587 (+)NCBIT2T-CHM13v2.0
Rph3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395121,078,562 - 121,184,249 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5121,078,562 - 121,148,155 (-)EnsemblGRCm39 Ensembl
GRCm385120,940,499 - 121,010,116 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5120,940,499 - 121,010,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv375121,390,508 - 121,459,527 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365121,201,116 - 121,270,135 (-)NCBIMGSCv36mm8
Celera5118,026,782 - 118,095,964 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map561.17NCBI
Rph3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81241,203,004 - 41,279,536 (+)NCBIGRCr8
mRatBN7.21235,542,389 - 35,618,901 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1235,542,728 - 35,617,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1236,721,473 - 36,796,064 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01237,332,667 - 37,407,266 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01236,385,126 - 36,459,717 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01241,073,296 - 41,149,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1241,073,824 - 41,148,490 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,938,832 - 43,014,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,678,613 - 36,753,316 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11236,542,000 - 36,616,704 (+)NCBI
Celera1237,205,019 - 37,281,023 (+)NCBICelera
Cytogenetic Map12q16NCBI
RPH3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210120,667,296 - 120,988,275 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112120,663,693 - 120,984,671 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012110,393,495 - 110,504,099 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112113,766,871 - 113,888,805 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12113,815,437 - 113,886,701 (+)Ensemblpanpan1.1panPan2
RPH3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12610,147,910 - 10,379,742 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2610,280,850 - 10,378,061 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2610,232,289 - 10,497,349 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02610,490,689 - 10,619,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2610,405,323 - 10,619,145 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12610,327,807 - 10,592,901 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02610,527,647 - 10,656,100 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02610,439,243 - 10,704,531 (+)NCBIUU_Cfam_GSD_1.0
Rph3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118148,328,663 - 148,413,066 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366682,857,732 - 2,911,517 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366682,827,574 - 2,911,955 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPH3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1438,867,099 - 38,969,169 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11438,867,095 - 39,162,052 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21441,316,538 - 41,482,994 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPH3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111107,818,594 - 108,155,546 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11108,077,043 - 108,155,539 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037136,930,533 - 137,267,850 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rph3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474719,441,226 - 19,495,798 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474719,439,365 - 19,657,865 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014467   ⟹   ENSCLAP00000014309
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554829,225,845 - 9,312,695 (+)Ensembl
RefSeq Acc Id: XM_005403200   ⟹   XP_005403257
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,243,692 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403201   ⟹   XP_005403258
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,243,692 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403202   ⟹   XP_005403259
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,243,970 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403203   ⟹   XP_005403260
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,243,970 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403204   ⟹   XP_005403261
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,251,855 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403205   ⟹   XP_005403262
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,253,546 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403206   ⟹   XP_005403263
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,225,523 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403207   ⟹   XP_005403264
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,204,786 - 9,312,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013503738   ⟹   XP_013359192
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554829,190,137 - 9,312,596 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005403264   ⟸   XM_005403207
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VG22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403263   ⟸   XM_005403206
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VG22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403257   ⟸   XM_005403200
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005403258   ⟸   XM_005403201
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005403260   ⟸   XM_005403203
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005403259   ⟸   XM_005403202
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005403261   ⟸   XM_005403204
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005403262   ⟸   XM_005403205
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013359192   ⟸   XM_013503738
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VG22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000014309   ⟸   ENSCLAT00000014467
Protein Domains
C2   FYVE-type   RabBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009863 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014467 ENTREZGENE
  ENSCLAT00000014467.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  FYVE_2 UniProtKB/TrEMBL
  Rab_BD UniProtKB/TrEMBL
  Rabphilin/DOC2/Noc2 UniProtKB/TrEMBL
  Rabphilin_Doc2_C2A UniProtKB/TrEMBL
  RPH3A UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Rph3a ENTREZGENE
PANTHER PTHR45729 UniProtKB/TrEMBL
  PTHR45729:SF3 UniProtKB/TrEMBL
Pfam FYVE_2 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
  RABBD UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A8C2VG22 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Rph3a  rabphilin 3A    rabphilin 3A homolog (mouse)  Symbol and/or name change 5135510 APPROVED