Rap1gds1 (Rap1 GTPase-GDP dissociation stimulator 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rap1gds1 (Rap1 GTPase-GDP dissociation stimulator 1) Chinchilla lanigera
Analyze
Symbol: Rap1gds1
Name: Rap1 GTPase-GDP dissociation stimulator 1
RGD ID: 8715687
Description: ENCODES a protein that exhibits GTPase regulator activity (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN angiotensin-activated signaling pathway involved in heart process (ortholog); CAAX-box protein maturation (ortholog); cardiac muscle hypertrophy (ortholog); ASSOCIATED WITH ALFADHEL SYNDROME (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog); endoplasmic reticulum (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RAP1, GTP-GDP dissociation stimulator 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554058,573,932 - 8,709,990 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554058,555,117 - 8,708,604 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rap1gds1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554058,573,932 - 8,709,990 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554058,555,117 - 8,708,604 (+)NCBIChiLan1.0ChiLan1.0
RAP1GDS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38498,261,384 - 98,443,858 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl498,261,384 - 98,443,858 (+)EnsemblGRCh38hg38GRCh38
GRCh37499,182,535 - 99,365,009 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36499,401,550 - 99,584,035 (+)NCBINCBI36Build 36hg18NCBI36
Build 34499,539,797 - 99,720,993NCBI
Celera496,477,193 - 96,659,685 (+)NCBICelera
Cytogenetic Map4q23NCBI
HuRef494,951,921 - 95,102,454 (+)NCBIHuRef
CHM1_1499,159,390 - 99,341,882 (+)NCBICHM1_1
T2T-CHM13v2.04101,576,339 - 101,758,825 (+)NCBIT2T-CHM13v2.0
Rap1gds1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393138,631,662 - 138,781,163 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3138,631,663 - 138,780,962 (-)EnsemblGRCm39 Ensembl
GRCm383138,925,897 - 139,075,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,925,902 - 139,075,201 (-)EnsemblGRCm38mm10GRCm38
MGSCv373138,588,870 - 138,738,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,863,297 - 139,012,457 (-)NCBIMGSCv36mm8
Celera3145,353,564 - 145,478,788 (-)NCBICelera
Cytogenetic Map3H1NCBI
cM Map364.52NCBI
Rap1gds1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82230,173,713 - 230,318,555 (-)NCBIGRCr8
mRatBN7.22227,500,366 - 227,645,213 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2227,500,367 - 227,645,169 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2235,242,317 - 235,354,991 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02233,142,077 - 233,254,755 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02228,006,680 - 228,119,360 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02244,258,550 - 244,370,983 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2244,258,550 - 244,370,983 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,787,595 - 262,899,803 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42236,522,381 - 236,638,692 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12236,510,838 - 236,657,572 (-)NCBI
Celera2219,646,515 - 219,757,722 (-)NCBICelera
Cytogenetic Map2q44NCBI
RAP1GDS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2396,336,451 - 96,509,923 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1496,614,421 - 96,787,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0490,671,891 - 90,846,501 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14101,336,286 - 101,510,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4101,336,286 - 101,510,517 (+)Ensemblpanpan1.1panPan2
RAP1GDS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13220,536,812 - 20,690,433 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3220,534,699 - 20,688,950 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3221,241,083 - 21,401,128 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03220,718,694 - 20,878,364 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13220,687,721 - 20,847,099 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03220,513,396 - 20,672,839 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03219,224,102 - 19,383,998 (-)NCBIUU_Cfam_GSD_1.0
Rap1gds1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530121,016,077 - 21,163,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936717233,696 - 380,963 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936717233,696 - 380,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAP1GDS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8121,866,805 - 122,082,948 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18121,866,803 - 122,007,492 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28131,053,654 - 131,110,270 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAP1GDS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1746,410,057 - 46,581,866 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl746,410,084 - 46,583,028 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603724,841,556 - 25,014,216 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rap1gds1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475726,393,106 - 26,520,785 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475726,393,116 - 26,520,344 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000006537   ⟹   ENSCLAP00000006430
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554058,573,932 - 8,709,990 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000006538   ⟹   ENSCLAP00000006431
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554058,573,932 - 8,709,990 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000006539   ⟹   ENSCLAP00000006432
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554058,581,869 - 8,706,982 (+)Ensembl
RefSeq Acc Id: XM_013517446   ⟹   XP_013372900
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554058,555,117 - 8,708,604 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013517447   ⟹   XP_013372901
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554058,555,117 - 8,708,604 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013372900 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372901 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006430
  ENSCLAP00000006430.1
  ENSCLAP00000006431.1
  ENSCLAP00000006432.1
Reference Protein Sequences
RefSeq Acc Id: XP_013372900   ⟸   XM_013517446
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UWP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013372901   ⟸   XM_013517447
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UWP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000006432   ⟸   ENSCLAT00000006539
RefSeq Acc Id: ENSCLAP00000006431   ⟸   ENSCLAT00000006538
RefSeq Acc Id: ENSCLAP00000006430   ⟸   ENSCLAT00000006537


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004545 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006537 ENTREZGENE
  ENSCLAT00000006537.1 UniProtKB/TrEMBL
  ENSCLAT00000006538.1 UniProtKB/TrEMBL
  ENSCLAT00000006539.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  RAP1GDS1 UniProtKB/TrEMBL
NCBI Gene Rap1gds1 ENTREZGENE
PANTHER PTHR10957 UniProtKB/TrEMBL
  RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
PROSITE ARM_REPEAT UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C2UWP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YL08_CHILA UniProtKB/TrEMBL
  A0A8C2YL09_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Rap1gds1  Rap1 GTPase-GDP dissociation stimulator 1    RAP1, GTP-GDP dissociation stimulator 1  Symbol and/or name change 5135510 APPROVED