Klln (killin, p53-regulated DNA replication inhibitor) - Rat Genome Database

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Gene: Klln (killin, p53-regulated DNA replication inhibitor) Rattus norvegicus
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Symbol: Klln
Name: killin, p53-regulated DNA replication inhibitor
RGD ID: 7720631
Description: Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in Cowden syndrome 4. Orthologous to human KLLN (killin, p53 regulated DNA replication inhibitor); INTERACTS WITH 17beta-estradiol (ortholog); aflatoxin B1 (ortholog); Aflatoxin B2 alpha (ortholog).
Type: protein-coding
Previously known as: hypothetical protein LOC681340; killin; killin-like; LOC102551694; LOC681340
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01251,417,849 - 251,420,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01258,647,937 - 258,650,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,769,513 - 236,770,244 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1227,742,357 - 227,745,527 (-)NCBICelera
Cytogenetic Map1q52NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)

References
Additional References at PubMed
PMID:23418309  


Genomics

Comparative Map Data
Klln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01251,417,849 - 251,420,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01258,647,937 - 258,650,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41236,769,513 - 236,770,244 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1227,742,357 - 227,745,527 (-)NCBICelera
Cytogenetic Map1q52NCBI
KLLN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381087,859,158 - 87,863,533 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1087,859,158 - 87,863,533 (-)EnsemblGRCh38hg38GRCh38
GRCh371089,618,915 - 89,623,290 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera1083,365,399 - 83,369,675 (-)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1083,253,736 - 83,258,012 (-)NCBIHuRef
CHM1_11089,901,216 - 89,905,492 (-)NCBICHM1_1
T2T-CHM13v2.01088,743,061 - 88,747,436 (-)NCBIT2T-CHM13v2.0
Gm36566
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391932,731,847 - 32,734,812 (-)NCBIGRCm39GRCm39mm39
GRCm381932,754,447 - 32,757,412 (-)NCBIGRCm38GRCm38mm10GRCm38
Celera1933,537,983 - 33,540,672 (-)NCBICelera
Cytogenetic Map19C1NCBI
KLLN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2899,874,645 - 99,880,229 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11099,879,961 - 99,885,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01084,581,971 - 84,587,420 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11088,088,758 - 88,093,022 (-)NCBIpanpan1.1PanPan1.1panPan2
KLLN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11499,923,996 - 99,928,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214108,906,728 - 108,910,350 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLLN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1981,304,883 - 81,307,162 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604841,969,440 - 41,972,581 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klln
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479113,964,043 - 13,966,743 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_017590484   ⟹   XP_017445973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01251,417,849 - 251,420,794 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017604897   ⟹   XP_017460386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1227,742,357 - 227,745,527 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7720631 AgrOrtholog
NCBI Gene LOC102551694 ENTREZGENE
PhenoGen Klln PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-26 Klln  killin, p53-regulated DNA replication inhibitor  LOC102551694  killin-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 LOC102551694  killin-like  LOC681340  hypothetical protein LOC681340  Data merged from RGD:1596750 737654 PROVISIONAL
2013-12-18 LOC102551694  killin-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681340  hypothetical protein LOC681340      Symbol and Name status set to provisional 70820 PROVISIONAL