Rex2l4 (reduced expression 2 like 4) - Rat Genome Database

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Gene: Rex2l4 (reduced expression 2 like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rex2l4 (Ensembl: LOC102551014)
Name: reduced expression 2 like 4 (Ensembl:zinc finger protein 624-like)
RGD ID: 7623967
Description: Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102551014; reduced expression 2 like 3; Rex2l3; zinc finger protein 624-like; zinc finger protein 664-like; zinc finger protein with KRAB and SCAN domains 1-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85162,695,137 - 162,730,581 (-)NCBIGRCr8
mRatBN7.25157,422,388 - 157,447,357 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5157,422,422 - 157,447,336 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05163,506,732 - 163,530,630 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05167,180,376 - 167,204,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5155,711,971 - 155,768,062 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Rex2l4
321 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5151006154161165494Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_008764328   ⟹   XP_008762550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,728,489 (-)NCBI
mRatBN7.25157,422,388 - 157,445,293 (-)NCBI
Rnor_6.05163,506,732 - 163,530,630 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039111337   ⟹   XP_038967265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,581 (-)NCBI
mRatBN7.25157,422,388 - 157,447,332 (-)NCBI
RefSeq Acc Id: XM_039111338   ⟹   XP_038967266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,520 (-)NCBI
mRatBN7.25157,422,388 - 157,447,333 (-)NCBI
RefSeq Acc Id: XM_039111339   ⟹   XP_038967267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,537 (-)NCBI
mRatBN7.25157,422,388 - 157,447,357 (-)NCBI
RefSeq Acc Id: XM_063288645   ⟹   XP_063144715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,550 (-)NCBI
RefSeq Acc Id: XM_063288646   ⟹   XP_063144716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,519 (-)NCBI
RefSeq Acc Id: XM_063288647   ⟹   XP_063144717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85162,695,137 - 162,730,520 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008762550   ⟸   XM_008764328
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_038967267   ⟸   XM_039111339
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967266   ⟸   XM_039111338
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967265   ⟸   XM_039111337
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ABM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144715   ⟸   XM_063288645
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ABM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144717   ⟸   XM_063288647
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063144716   ⟸   XM_063288646
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ABM4 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   KRAB

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-39245 BioCyc
Ensembl Genes ENSRNOG00000059160 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000101465.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC102551014 ENTREZGENE
PANTHER ZINC FINGER PROTEIN 845-LIKE UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZIC AND GLI UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Rex2l4 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059160 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I6ABM4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rex2l4  reduced expression 2 like 4  Rex2l3  reduced expression 2 like 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rex2l3  reduced expression 2 like 3  LOC102551014  zinc finger protein 624-like  Symbol and Name Changed 1299863 APPROVED
2013-12-18 LOC102551014  zinc finger protein 624-like      Symbol and Name status set to provisional 70820 PROVISIONAL