Smokwl5 (sperm motility kinase W like 5) - Rat Genome Database

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Gene: Smokwl5 (sperm motility kinase W like 5) Rattus norvegicus
Analyze
Symbol: Smokwl5 (Ensembl: LOC102551633)
Name: sperm motility kinase W like 5 (Ensembl:sperm motility kinase W-like)
RGD ID: 7576862
Description: Predicted to enable protein serine/threonine kinase activity.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102551633; putative sperm motility kinase W; sperm motility kinase W-like
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8715,843,248 - 15,879,257 (-)NCBIGRCr8
mRatBN7.2715,108,038 - 15,144,009 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl715,132,234 - 15,144,051 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0720,034,759 - 20,070,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl720,068,974 - 20,070,772 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0720,240,138 - 20,241,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera714,025,786 - 14,061,861 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Variants

.
Variants in Smokwl5
83 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000071008
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system appendage
High
Medium 2
Low 5
Below cutoff 4 1 3 1 1 1 2 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006225975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001838756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000071008   ⟹   ENSRNOP00000065299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl715,132,234 - 15,144,051 (-)Ensembl
Rnor_6.0 Ensembl720,068,974 - 20,070,772 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100612   ⟹   ENSRNOP00000083426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl715,132,234 - 15,144,051 (-)Ensembl
RefSeq Acc Id: XM_039080488   ⟹   XP_038936416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,866,647 - 15,879,257 (-)NCBI
mRatBN7.2715,126,749 - 15,144,009 (-)NCBI
RefSeq Acc Id: XM_063264499   ⟹   XP_063120569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,866,647 - 15,879,257 (-)NCBI
RefSeq Acc Id: XM_063264500   ⟹   XP_063120570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,861,104 - 15,879,257 (-)NCBI
RefSeq Acc Id: XM_063264502   ⟹   XP_063120572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,843,248 - 15,879,257 (-)NCBI
RefSeq Acc Id: XM_063264503   ⟹   XP_063120573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8715,866,647 - 15,879,257 (-)NCBI
RefSeq Acc Id: ENSRNOP00000065299   ⟸   ENSRNOT00000071008
RefSeq Acc Id: XP_038936416   ⟸   XM_039080488
- UniProtKB: M0R777 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000083426   ⟸   ENSRNOT00000100612
RefSeq Acc Id: XP_063120572   ⟸   XM_063264502
RefSeq Acc Id: XP_063120570   ⟸   XM_063264500
RefSeq Acc Id: XP_063120569   ⟸   XM_063264499
RefSeq Acc Id: XP_063120573   ⟸   XM_063264503
Protein Domains
Protein kinase   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R777-F1-model_v2 AlphaFold M0R777 1-474 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7576862 AgrOrtholog
BioCyc Gene G2FUF-34699 BioCyc
Ensembl Genes ENSRNOG00000050249 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071008.3 UniProtKB/TrEMBL
  ENSRNOT00000100612.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
NCBI Gene LOC102551633 ENTREZGENE
PANTHER KP78A-RELATED UniProtKB/TrEMBL
  MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Smokwl5 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050249 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt M0R777 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Smokwl5  sperm motility kinase W like 5  LOC102551633  sperm motility kinase W-like  Symbol and Name Changed 1299863 APPROVED
2013-12-18 LOC102551633  sperm motility kinase W-like      Symbol and Name status set to provisional 70820 PROVISIONAL