Plekhg7 (pleckstrin homology and RhoGEF domain containing G7) - Rat Genome Database

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Gene: Plekhg7 (pleckstrin homology and RhoGEF domain containing G7) Rattus norvegicus
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Symbol: Plekhg7
Name: pleckstrin homology and RhoGEF domain containing G7
RGD ID: 7576392
Description: Orthologous to human PLEKHG7 (pleckstrin homology and RhoGEF domain containing G7); INTERACTS WITH benzo[a]pyrene (ortholog); FR900359 (ortholog); N-Nitrosopyrrolidine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102549681; LOC102549785; pleckstrin homology domain-containing family G member 7; pleckstrin homology domain-containing family G member 7-like; uncharacterized LOC102549785
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8732,614,744 - 32,692,659 (-)NCBIGRCr8
mRatBN7.2730,727,952 - 30,805,866 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0737,192,898 - 37,218,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0737,239,572 - 37,261,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera727,788,426 - 27,814,528 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
Plekhg7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8732,614,744 - 32,692,659 (-)NCBIGRCr8
mRatBN7.2730,727,952 - 30,805,866 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0737,192,898 - 37,218,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0737,239,572 - 37,261,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera727,788,426 - 27,814,528 (-)NCBICelera
Cytogenetic Map7q13NCBI
PLEKHG7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381292,702,989 - 92,772,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1292,702,843 - 92,772,455 (+)EnsemblGRCh38hg38GRCh38
GRCh371293,096,765 - 93,166,231 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361291,654,442 - 91,689,999 (+)NCBINCBI36Build 36hg18NCBI36
Celera1292,801,387 - 92,836,959 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1290,197,665 - 90,233,278 (+)NCBIHuRef
CHM1_11293,094,968 - 93,130,572 (+)NCBICHM1_1
T2T-CHM13v2.01292,680,461 - 92,750,036 (+)NCBIT2T-CHM13v2.0
Gm49817
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,888,057 - 95,962,580 (-)NCBIGRCm39GRCm39mm39
Cytogenetic Map10C2NCBI
Plekhg7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540529,703,523 - 29,760,551 (+)NCBIChiLan1.0ChiLan1.0
PLEKHG7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210100,730,330 - 100,799,021 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112100,726,723 - 100,795,414 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01290,230,561 - 90,299,248 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11293,575,931 - 93,611,209 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1293,542,646 - 93,548,351 (+)Ensemblpanpan1.1panPan2
PLEKHG7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,113,668 - 33,142,444 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1533,516,847 - 33,595,075 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01533,740,180 - 33,812,104 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11533,020,823 - 33,091,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,077,422 - 33,180,431 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01533,365,863 - 33,444,298 (+)NCBIUU_Cfam_GSD_1.0
Plekhg7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494526,905,577 - 26,967,715 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365079,302,078 - 9,329,821 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHG7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1590,258,525 - 90,313,117 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2594,510,878 - 94,553,139 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHG7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11188,093,018 - 88,164,710 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1188,126,456 - 88,161,808 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037157,001,014 - 157,075,428 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhg7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475013,970,858 - 14,024,570 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekhg7
606 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_039080593   ⟹   XP_038936521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8732,614,744 - 32,692,659 (-)NCBI
mRatBN7.2730,727,952 - 30,805,866 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038936521 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_038936521   ⟸   XM_039080593


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7576392 AgrOrtholog
BioCyc Gene G2FUF-34311 BioCyc
NCBI Gene LOC102549681 ENTREZGENE
PhenoGen Plekhg7 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Plekhg7  pleckstrin homology and RhoGEF domain containing G7  LOC102549785  uncharacterized LOC102549785  Data merged from RGD:7594195 737654 PROVISIONAL
2016-01-11 Plekhg7  pleckstrin homology and RhoGEF domain containing G7  LOC102549681  pleckstrin homology domain-containing family G member 7-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102549785  uncharacterized LOC102549785      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-12-18 LOC102549681  pleckstrin homology domain-containing family G member 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL