Miat (myocardial infarction associated transcript) - Rat Genome Database

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Gene: Miat (myocardial infarction associated transcript) Rattus norvegicus
Analyze
Symbol: Miat
Name: myocardial infarction associated transcript
RGD ID: 7567380
Description: Predicted to act upstream of or within neurogenesis and stem cell population maintenance. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human MIAT (myocardial infarction associated transcript); INTERACTS WITH atrazine; isoprenaline; lutein.
Type: ncrna
RefSeq Status: REVIEWED
Previously known as: LOC102552664; myocardial infarction associated transcript (non-protein coding); uncharacterized LOC102552664
RGD Orthologs
Human
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,075,026 - 50,090,259 (+)NCBIGRCr8
mRatBN7.21244,414,620 - 44,429,852 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1245,583,840 - 45,599,051 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,193,881 - 46,209,114 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,254,414 - 45,269,645 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01250,447,251 - 50,461,859 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01252,200,260 - 52,215,704 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1245,997,418 - 46,012,587 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear body  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Long noncoding RNA myocardial infarction associated transcript promotes the development of thoracic aortic by targeting microRNA-145 via the PI3K/Akt signaling pathway. Chen S, etal., J Cell Biochem. 2019 Sep;120(9):14405-14413. doi: 10.1002/jcb.28695. Epub 2019 Apr 15.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16877424   PMID:20026622   PMID:20459797   PMID:25145264   PMID:25587098   PMID:26551455   PMID:28703801   PMID:29486902   PMID:30563429   PMID:30660685   PMID:30895947   PMID:31344482  
PMID:31628679   PMID:31661125   PMID:31858562   PMID:32210708   PMID:32964992   PMID:33741460   PMID:33745924   PMID:34514556   PMID:34687132   PMID:34713933   PMID:35636204   PMID:35641779  


Genomics

Comparative Map Data
Miat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,075,026 - 50,090,259 (+)NCBIGRCr8
mRatBN7.21244,414,620 - 44,429,852 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx1245,583,840 - 45,599,051 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,193,881 - 46,209,114 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,254,414 - 45,269,645 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01250,447,251 - 50,461,859 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01252,200,260 - 52,215,704 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1245,997,418 - 46,012,587 (+)NCBICelera
Cytogenetic Map12q16NCBI
MIAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382226,646,429 - 26,676,478 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2226,646,411 - 26,676,475 (+)EnsemblGRCh38hg38GRCh38
GRCh372227,053,446 - 27,072,441 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362225,383,484 - 25,402,438 (+)NCBINCBI36Build 36hg18NCBI36
Celera2210,857,234 - 10,876,230 (+)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef2210,000,978 - 10,020,593 (+)NCBIHuRef
CHM1_12227,013,019 - 27,032,077 (+)NCBICHM1_1
T2T-CHM13v2.02227,109,028 - 27,139,053 (+)NCBIT2T-CHM13v2.0
Miat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395112,361,094 - 112,376,814 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5112,361,094 - 112,377,261 (-)EnsemblGRCm39 Ensembl
GRCm385112,213,228 - 112,228,948 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5112,213,228 - 112,229,395 (-)EnsemblGRCm38mm10GRCm38
MGSCv375112,642,248 - 112,657,968 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365112,461,727 - 112,469,299 (-)NCBIMGSCv36mm8
Celera5109,333,060 - 109,348,469 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map554.59NCBI

Variants

.
Variants in Miat
77 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_111959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NR_111959
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81250,075,026 - 50,090,259 (+)NCBI
mRatBN7.21244,414,620 - 44,429,852 (+)NCBI
Rnor_6.01250,447,251 - 50,461,859 (+)NCBI
Celera1245,997,418 - 46,012,587 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7567380 AgrOrtholog
BioCyc Gene G2FUF-18861 BioCyc
NCBI Gene LOC102552664 ENTREZGENE
PhenoGen Miat PhenoGen
RNAcentral URS000075AA07 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-25 Miat  myocardial infarction associated transcript  Miat  myocardial infarction associated transcript (non-protein coding)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-04-10 Miat  Name: myocardial infarction associated transcript (non-protein coding)  LOC102552664  uncharacterized LOC102552664  Name and Symbol changed 629549 APPROVED
2014-04-10 Miat  myocardial infarction associated transcript (non-protein coding)  LOC102552664  uncharacterized LOC102552664  Name and Symbol changed 629549 APPROVED
2013-12-18 LOC102552664  uncharacterized LOC102552664      Symbol and Name status set to provisional 70820 PROVISIONAL