Gcnt7 (glucosaminyl (N-acetyl) transferase family member 7) - Rat Genome Database

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Gene: Gcnt7 (glucosaminyl (N-acetyl) transferase family member 7) Rattus norvegicus
Analyze
Symbol: Gcnt7
Name: glucosaminyl (N-acetyl) transferase family member 7
RGD ID: 7496421
Description: Predicted to enable acetylglucosaminyltransferase activity. Predicted to be located in Golgi membrane. Orthologous to human GCNT7 (glucosaminyl (N-acetyl) transferase family member 7); INTERACTS WITH trichloroethene; vinclozolin; (+)-catechin (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta 1,6-N-acetylglucosaminyltransferase; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7-like; gcnt; LOC102550196
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83181,637,406 - 181,647,839 (-)NCBIGRCr8
mRatBN7.23161,218,985 - 161,223,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,211,853 - 161,227,230 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03170,454,758 - 170,464,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3170,455,492 - 170,458,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03176,530,184 - 176,534,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3160,419,002 - 160,428,279 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Gcnt7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83181,637,406 - 181,647,839 (-)NCBIGRCr8
mRatBN7.23161,218,985 - 161,223,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,211,853 - 161,227,230 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03170,454,758 - 170,464,047 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3170,455,492 - 170,458,676 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03176,530,184 - 176,534,274 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3160,419,002 - 160,428,279 (-)NCBICelera
Cytogenetic Map3q42NCBI
GCNT7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382056,491,492 - 56,525,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2056,491,492 - 56,525,925 (-)EnsemblGRCh38hg38GRCh38
GRCh372055,066,548 - 55,100,981 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,499,955 - 54,534,613 (-)NCBINCBI36Build 36hg18NCBI36
Celera2051,806,975 - 51,841,413 (-)NCBICelera
Cytogenetic Map20q13.31NCBI
HuRef2051,851,237 - 51,885,668 (-)NCBIHuRef
CHM1_12054,967,671 - 55,002,093 (-)NCBICHM1_1
T2T-CHM13v2.02058,268,986 - 58,303,419 (-)NCBIT2T-CHM13v2.0
Gcnt7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392172,292,233 - 172,302,481 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2172,292,233 - 172,300,516 (-)EnsemblGRCm39 Ensembl
GRCm382172,450,242 - 172,458,596 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,450,313 - 172,458,596 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,275,813 - 172,284,096 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362172,141,518 - 172,149,801 (-)NCBIMGSCv36mm8
Celera2178,412,133 - 178,420,480 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.87NCBI
Gcnt7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554452,744,200 - 2,749,317 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554452,737,228 - 2,750,104 (+)NCBIChiLan1.0ChiLan1.0
LOC100977271
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22162,241,378 - 62,255,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12062,233,435 - 62,240,722 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02052,831,929 - 52,838,906 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12054,119,847 - 54,125,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2054,119,847 - 54,125,908 (-)Ensemblpanpan1.1panPan2
LOC102156144
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12441,682,401 - 41,710,602 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2441,684,750 - 41,696,031 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2440,929,945 - 40,958,137 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02442,445,196 - 42,473,366 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2442,446,142 - 42,458,884 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12441,632,674 - 41,660,855 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02441,771,806 - 41,800,120 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02442,429,996 - 42,458,404 (-)NCBIUU_Cfam_GSD_1.0
LOC101955949
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640183,692,321 - 183,698,924 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936875387,034 - 393,637 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936875387,034 - 394,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GCNT7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1757,061,805 - 57,068,505 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11757,061,805 - 57,074,637 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21764,172,717 - 64,187,264 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103243819
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.127,621,135 - 7,627,120 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl27,620,626 - 7,626,696 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605055,661,014 - 55,700,929 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Gcnt7
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:22
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000035071, ENSRNOT00000072742
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3161192952169034231Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 9 25 9 19 9 7 7 11 10 11 11 7
Below cutoff 12 8 8 8 1 3 1 12 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000035071   ⟹   ENSRNOP00000029664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3170,455,492 - 170,458,676 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108801   ⟹   ENSRNOP00000084778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3161,211,853 - 161,227,230 (-)Ensembl
RefSeq Acc Id: NM_001419536   ⟹   NP_001406465
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83181,637,406 - 181,641,460 (-)NCBI
mRatBN7.23161,218,985 - 161,223,039 (-)NCBI
RefSeq Acc Id: XM_063282977   ⟹   XP_063139047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83181,637,406 - 181,647,839 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001406465 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139047 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAK20457 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084778
  ENSRNOP00000084778.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000029664   ⟸   ENSRNOT00000035071
RefSeq Acc Id: ENSRNOP00000084778   ⟸   ENSRNOT00000108801
RefSeq Acc Id: NP_001406465   ⟸   NM_001419536
- UniProtKB: F2Z6J7 (UniProtKB/TrEMBL),   D3ZBX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139047   ⟸   XM_063282977
- Peptide Label: isoform X1
- UniProtKB: D3ZBX5 (UniProtKB/TrEMBL),   F2Z6J7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBX5-F1-model_v2 AlphaFold D3ZBX5 1-429 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7496421 AgrOrtholog
BioCyc Gene G2FUF-46537 BioCyc
BioCyc Pathway PWY-7433 [mucin core 1 and core 2 O-glycosylation] BioCyc
BioCyc Pathway Image PWY-7433 BioCyc
Ensembl Genes ENSRNOG00000021551 Ensembl
  ENSRNOG00000063099 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000108801 ENTREZGENE
  ENSRNOT00000108801.1 UniProtKB/TrEMBL
InterPro Glyco_trans_14 UniProtKB/TrEMBL
KEGG Report rno:102550196 UniProtKB/TrEMBL
NCBI Gene LOC102550196 ENTREZGENE
PANTHER BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE 7 UniProtKB/TrEMBL
  GLYCOSYLTRANSFERASE 14 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Branch UniProtKB/TrEMBL
PhenoGen Gcnt7 PhenoGen
RatGTEx ENSRNOG00000021551 RatGTEx
  ENSRNOG00000063099 RatGTEx
UniProt A6KKX5_RAT UniProtKB/TrEMBL
  D3ZBX5 ENTREZGENE, UniProtKB/TrEMBL
  F2Z6J7 ENTREZGENE
UniProt Secondary F2Z6J7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Gcnt7  glucosaminyl (N-acetyl) transferase family member 7  Gcnt7  glucosaminyl (N-acetyl) transferase family member 7  Data merged from RGD:149736178 737654 PROVISIONAL
2021-08-09 Gcnt7  glucosaminyl (N-acetyl) transferase family member 7      Symbol and Name status set to provisional 45752 PROVISIONAL
2015-07-01 Gcnt7  glucosaminyl (N-acetyl) transferase family member 7  LOC102550196  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102550196  beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7-like      Symbol and Name status set to provisional 70820 PROVISIONAL