Hadh (hydroxyacyl-Coenzyme A dehydrogenase) - Rat Genome Database

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Gene: Hadh (hydroxyacyl-Coenzyme A dehydrogenase) Mus musculus
Analyze
Symbol: Hadh
Name: hydroxyacyl-Coenzyme A dehydrogenase
RGD ID: 737567
MGI Page MGI
Description: Enables 3-hydroxyacyl-CoA dehydrogenase activity. Involved in positive regulation of cold-induced thermogenesis and regulation of insulin secretion. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA409008; AU019341; AW742602; Hadhsc; HCDH; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; hydroxylacyl-Coenzyme A dehydrogenase; hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain; medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Sch; Schad; short chain 3-hydroxyacyl-CoA dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393131,027,068 - 131,065,750 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3131,027,068 - 131,065,750 (-)EnsemblGRCm39 Ensembl
GRCm383131,233,419 - 131,272,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3131,233,419 - 131,272,101 (-)EnsemblGRCm38mm10GRCm38
MGSCv373130,936,342 - 130,974,955 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363131,222,610 - 131,261,182 (-)NCBIMGSCv36mm8
Celera3137,754,696 - 137,793,253 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map360.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
(R)-adrenaline  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (ISO)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (EXP)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
carbon nanotube  (EXP)
carmustine  (ISO)
cefaloridine  (ISO)
CGP 52608  (ISO)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP)
dibutyl phthalate  (EXP,ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenamidone  (EXP)
fenofibrate  (ISO)
fenvalerate  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
indinavir  (EXP)
indometacin  (ISO)
inulin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lamivudine  (EXP)
menadione  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
microcystin-LR  (EXP)
milrinone  (ISO)
Muraglitazar  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
nitric oxide  (EXP)
nitrofen  (ISO)
oleic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
PhIP  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (EXP,ISO)
progesterone  (ISO)
propan-2-ol  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
saquinavir  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
sulfadimethoxine  (ISO)
tauroursodeoxycholic acid  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tributylstannane  (EXP)
Tributyltin oxide  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Different forms of obesity as a function of diet composition. Dourmashkin JT, etal., Int J Obes (Lond). 2005 Nov;29(11):1368-78.
2. Serial evaluation of fatty acid metabolism in rats with myocardial infarction by pinhole SPECT. Hirai T, etal., J Nucl Cardiol. 2001 Jul-Aug;8(4):472-81.
3. Effects of streptozotocin diabetes, insulin treatment, and training on the diaphragm. Ianuzzo CD, etal., J Appl Physiol. 1982 Jun;52(6):1471-5.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
6. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
7. Specificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin release. Martens GA, etal., J Biol Chem. 2007 Jul 20;282(29):21134-44. Epub 2007 May 9.
8. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation. Molven A, etal., Diabetes. 2004 Jan;53(1):221-7.
11. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. Mouse MP Annotation Import Pipeline RGD automated import pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7642117   PMID:8070621   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12865426   PMID:14610273   PMID:14681479  
PMID:15226823   PMID:15236401   PMID:15240869   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16916647   PMID:17185391   PMID:18614015   PMID:18799693   PMID:20670938  
PMID:21267068   PMID:21873635   PMID:21990309   PMID:22496890   PMID:25662615   PMID:26767982   PMID:26953163   PMID:28378742   PMID:29669786   PMID:29688375   PMID:30333137   PMID:30550785  
PMID:31146259   PMID:32325033   PMID:34321999   PMID:35081489   PMID:36293380   PMID:36398584   PMID:37392854  


Genomics

Comparative Map Data
Hadh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393131,027,068 - 131,065,750 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3131,027,068 - 131,065,750 (-)EnsemblGRCm39 Ensembl
GRCm383131,233,419 - 131,272,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3131,233,419 - 131,272,101 (-)EnsemblGRCm38mm10GRCm38
MGSCv373130,936,342 - 130,974,955 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363131,222,610 - 131,261,182 (-)NCBIMGSCv36mm8
Celera3137,754,696 - 137,793,253 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map360.86NCBI
HADH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384107,989,889 - 108,035,171 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4107,989,714 - 108,035,241 (+)EnsemblGRCh38hg38GRCh38
GRCh374108,911,045 - 108,956,327 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364109,130,389 - 109,175,780 (+)NCBINCBI36Build 36hg18NCBI36
Celera4106,205,689 - 106,251,144 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4104,642,283 - 104,687,973 (+)NCBIHuRef
CHM1_14108,887,327 - 108,932,780 (+)NCBICHM1_1
T2T-CHM13v2.04111,292,223 - 111,337,508 (+)NCBIT2T-CHM13v2.0
Hadh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,462,049 - 222,504,446 (-)NCBIGRCr8
mRatBN7.22219,787,935 - 219,830,335 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2219,787,927 - 219,830,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,444,166 - 227,486,582 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,343,838 - 225,386,248 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,201,461 - 220,243,878 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,353,445 - 236,395,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,353,445 - 236,395,067 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02254,902,140 - 254,944,001 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,698,545 - 228,751,691 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,685,284 - 228,738,431 (-)NCBI
Celera2212,044,254 - 212,086,368 (-)NCBICelera
Cytogenetic Map2q43NCBI
Hadh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554961,835,034 - 1,861,407 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554961,835,034 - 1,861,410 (-)NCBIChiLan1.0ChiLan1.0
HADH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23106,088,578 - 106,133,957 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14106,383,480 - 106,428,851 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04100,495,205 - 100,540,589 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14111,067,537 - 111,112,945 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4111,067,336 - 111,113,868 (+)Ensemblpanpan1.1panPan2
HADH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13228,460,445 - 28,506,141 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3228,460,193 - 28,531,280 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3213,516,288 - 13,562,132 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03228,689,480 - 28,735,351 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3228,689,484 - 28,780,497 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13228,682,743 - 28,728,360 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03228,427,283 - 28,473,178 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03211,383,587 - 11,429,427 (-)NCBIUU_Cfam_GSD_1.0
Hadh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530112,605,927 - 12,654,203 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936818575,023 - 623,568 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936818575,272 - 623,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HADH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8113,950,034 - 114,005,511 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18113,952,561 - 114,005,510 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28122,212,898 - 122,265,850 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HADH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1755,919,499 - 55,965,074 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl755,919,623 - 55,964,857 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603734,546,087 - 34,591,597 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hadh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248301,426,775 - 1,451,440 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248301,429,989 - 1,451,447 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hadh
1456 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:432
Count of miRNA genes:313
Interacting mature miRNAs:359
Transcripts:ENSMUST00000029610, ENSMUST00000152427
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
12910793Pwbwq7_mpost-weaning body weight QTL 7 (mouse)3110084357135715812Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
12910796Pwbwq6_mpost-weaning body weight QTL 6 (mouse)3110084357135715812Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
12910815Ogrq1_moverall growth rate QTL 1 (mouse)3110084357135715812Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
26884415Bzwq11_mbi-zygomatic width QTL 11, 16 week (mouse)3124993649137205761Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1301805Mors2_mmodifier of obesity related sterility 2 (mouse)Not determined3103482659137482783Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse

Markers in Region
AW742602  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383131,233,535 - 131,233,779UniSTSGRCm38
MGSCv373130,936,453 - 130,936,697UniSTSGRCm37
Celera3137,754,807 - 137,755,051UniSTS
Cytogenetic Map3G3UniSTS
Whitehead/MRC_RH31483.83UniSTS
RH136485  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383131,233,561 - 131,233,777UniSTSGRCm38
MGSCv373130,936,479 - 130,936,695UniSTSGRCm37
Celera3137,754,833 - 137,755,049UniSTS
Cytogenetic Map3G3UniSTS
Hadh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv373130,936,514 - 130,936,671UniSTSGRCm37
Celera3137,754,868 - 137,755,025UniSTS
Cytogenetic Map3G3UniSTS
cM MapUN UniSTS
cM Map3 UniSTS
cM MapUN UniSTS
cM Map3 UniSTS
Hadh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383131,233,596 - 131,233,753UniSTSGRCm38
MGSCv373130,936,514 - 130,936,671UniSTSGRCm37
Celera3137,754,868 - 137,755,025UniSTS
Cytogenetic Map3G3UniSTS
cM MapUN UniSTS
cM Map3 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH010773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI845880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D29639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000029610   ⟹   ENSMUSP00000029610
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3131,027,068 - 131,065,750 (-)Ensembl
GRCm38.p6 Ensembl3131,233,419 - 131,272,101 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152427
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3131,038,750 - 131,065,673 (-)Ensembl
GRCm38.p6 Ensembl3131,245,101 - 131,272,024 (-)Ensembl
RefSeq Acc Id: NM_008212   ⟹   NP_032238
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393131,027,068 - 131,065,750 (-)NCBI
GRCm383131,233,419 - 131,272,101 (-)NCBI
MGSCv373130,936,342 - 130,974,955 (-)RGD
Celera3137,754,691 - 137,793,317 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032238   ⟸   NM_008212
- Peptide Label: precursor
- UniProtKB: Q8K149 (UniProtKB/Swiss-Prot),   Q3UFI0 (UniProtKB/Swiss-Prot),   Q3THK8 (UniProtKB/Swiss-Prot),   Q3TF75 (UniProtKB/Swiss-Prot),   Q925U9 (UniProtKB/Swiss-Prot),   Q61425 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029610   ⟸   ENSMUST00000029610

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61425-F1-model_v2 AlphaFold Q61425 1-314 view protein structure

Promoters
RGD ID:6833933
Promoter ID:MM_KWN:36112
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000071450,   UC008RJM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363130,974,689 - 130,975,189 (-)MPROMDB
RGD ID:6882384
Promoter ID:EPDNEW_M4643
Type:initiation region
Name:Hadh_1
Description:Mus musculus hydroxyacyl-Coenzyme A dehydrogenase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383131,272,027 - 131,272,087EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96009 AgrOrtholog
Ensembl Genes ENSMUSG00000027984 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000029610 ENTREZGENE
  ENSMUST00000029610.9 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
InterPro 3-OHacyl-CoA_DH UniProtKB/Swiss-Prot
  3-OHacyl-CoA_DH_CS UniProtKB/Swiss-Prot
  3-OHacyl-CoA_DH_NAD-bd UniProtKB/Swiss-Prot
  3HC_DH_C UniProtKB/Swiss-Prot
  6-PGluconate_DH-like_C_sf UniProtKB/Swiss-Prot
  6PGD_dom2 UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:15107 UniProtKB/Swiss-Prot
MGD MGI:96009 ENTREZGENE
NCBI Gene 15107 ENTREZGENE
PANTHER HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR43561 UniProtKB/Swiss-Prot
Pfam 3HCDH UniProtKB/Swiss-Prot
  3HCDH_N UniProtKB/Swiss-Prot
PhenoGen Hadh PhenoGen
PIRSF HCDH UniProtKB/Swiss-Prot
PROSITE 3HCDH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48179 UniProtKB/Swiss-Prot
  SSF51735 UniProtKB/Swiss-Prot
UniProt HCDH_MOUSE UniProtKB/Swiss-Prot
  Q3TF75 ENTREZGENE
  Q3THK8 ENTREZGENE
  Q3UFI0 ENTREZGENE
  Q61425 ENTREZGENE
  Q8K149 ENTREZGENE
  Q925U9 ENTREZGENE
UniProt Secondary Q3TF75 UniProtKB/Swiss-Prot
  Q3THK8 UniProtKB/Swiss-Prot
  Q3UFI0 UniProtKB/Swiss-Prot
  Q8K149 UniProtKB/Swiss-Prot
  Q925U9 UniProtKB/Swiss-Prot