ADNP (activity-dependent neuroprotector homeobox)

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Keyword

Gene: ADNP (activity-dependent neuroprotector homeobox) Homo sapiens

Symbol:

ADNP

Name:

activity-dependent neuroprotector homeobox

Description:

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

activity-dependent neuroprotective protein; activity-dependent neuroprotector homeobox protein; ADNP homeobox 1; ADNP1; KIAA0784; OTTHUMP00000031275; OTTHUMP00000031276; OTTHUMP00000165329; OTTHUMP00000229415

Orthologs:

Mus musculus : Adnp (activity-dependent neuroprotective protein) MGI
Rattus norvegicus : Adnp (activity-dependent neuroprotector homeobox)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	20	49,478,355 - 49,516,927	-	NCBI
Human Genome Assembly HuRef	20	46,255,283 - 46,295,816	-	NCBI
Human Genome Assembly GRCh37	20	49,506,883 - 49,547,527	-	NCBI
Human Celera Assembly	20	46,211,143 - 46,251,787	-	NCBI
Human Genome Assembly Build 36	20	48,940,290 - 48,980,934	-	NCBI
Human Cytogenetic Map	20	q13.13		NCBI
Human Genome Assembly	20	48,940,289 - 48,980,934		NCBI