CRTAC1 (cartilage acidic protein 1)

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Keyword

Gene: CRTAC1 (cartilage acidic protein 1) Homo sapiens

Symbol:

CRTAC1

Name:

cartilage acidic protein 1

Description:

This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

68 kDa chondrocyte-expressed protein; acidic secreted protein in cartilage; ASPIC; ASPIC; ASPIC1; cartilage acidic protein 1; CEP-68; chondrocyte expressed protein 68 kDa CEP-68; FLJ10320; OTTHUMP00000020233; OTTHUMP00000020234; OTTHUMP00000020235; w307 protein

Orthologs:

Mus musculus : Crtac1 (cartilage acidic protein 1) MGI
Rattus norvegicus : Crtac1 (cartilage acidic protein 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	10	99,986,467 - 100,152,360	-	NCBI
Human Genome Assembly HuRef	10	93,250,028 - 93,415,859	-	NCBI
Human Genome Assembly GRCh37	10	99,624,757 - 99,790,585	-	NCBI
Human Genome Assembly Build 36	10	99,614,748 - 99,780,575	-	NCBI
Human Cytogenetic Map	10	q22		NCBI
Human Genome Assembly	10	99,614,747 - 99,780,575		NCBI