HNRNPL (heterogeneous nuclear ribonucleoprotein L)

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Keyword

Gene: HNRNPL (heterogeneous nuclear ribonucleoprotein L) Homo sapiens

Symbol:

HNRNPL

Name:

heterogeneous nuclear ribonucleoprotein L

Description:

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

FLJ35509; heterogeneous nuclear ribonucleoprotein L; hnRNP L; hnRNP-L; HNRPL; P/OKcl.14

Orthologs:

Mus musculus : Hnrnpl (heterogeneous nuclear ribonucleoprotein L) MGI
Rattus norvegicus : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	19	39,476,023 - 39,492,069	-	NCBI
Human Genome Assembly HuRef	19	35,773,794 - 35,789,557	-	NCBI
Human Genome Assembly GRCh37	19	39,327,028 - 39,342,979	-	NCBI
Human Genome Assembly Build 36	19	44,018,868 - 44,034,819	-	NCBI
Human Cytogenetic Map	19	q13.2		NCBI
Human Genome Assembly	19	44,018,868 - 44,032,457		NCBI