Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | EXP | | 6480464 | o and p'-DDT results in increased expression of ELOB mRNA | CTD | PMID:24096037 | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | o and p'-DDT results in increased expression of ELOB mRNA | CTD | PMID:24096037 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOB mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ELOB mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of ELOB mRNA | CTD | PMID:24096037 | 17alpha-ethynylestradiol | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of ELOB mRNA | CTD | PMID:24096037 | 17beta-estradiol | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ELOB mRNA | CTD | PMID:16514628 | 17beta-estradiol | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of TCEB2 mRNA | CTD | PMID:32145629 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ELOB mRNA | CTD | PMID:19465110 and PMID:21354282 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Elob (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ELOB mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ELOB mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ELOB mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4,6-tribromophenol | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Elob (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ELOB mRNA | CTD | PMID:36041667 | 4,4'-sulfonyldiphenol | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | bisphenol S results in increased expression of ELOB protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of TCEB2 mRNA | CTD | PMID:30047161 | afimoxifene | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | afimoxifene results in decreased expression of ELOB mRNA | CTD | PMID:16514628 | ammonium chloride | affects expression | ISO | Elob (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of ELOB mRNA | CTD | PMID:16483693 | arsenite(3-) | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to ELOB mRNA] and arsenite promotes the reaction [G3BP1 protein binds to ELOB protein] | CTD | PMID:32406909 | benzo[a]pyrene | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ELOB mRNA | CTD | PMID:26238291 | benzo[a]pyrene | decreases methylation | ISO | ELOB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ELOB promoter | CTD | PMID:27901495 | bisphenol A | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ELOB mRNA and bisphenol A results in increased expression of TCEB2 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ELOB protein | CTD | PMID:34186270 and PMID:37567409 | bisphenol A | multiple interactions | ISO | Elob (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ELOB mRNA | CTD | PMID:36041667 | bisphenol A | affects expression | ISO | Elob (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ELOB mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ELOB protein | CTD | PMID:31675489 | bisphenol A | decreases methylation | ISO | ELOB (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ELOB gene | CTD | PMID:31601247 | bisphenol F | multiple interactions | ISO | Elob (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ELOB mRNA | CTD | PMID:36041667 | butanal | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ELOB mRNA | CTD | PMID:26079696 | cadmium atom | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Cadmium results in decreased expression of ELOB mRNA | CTD | PMID:24284285 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ELOB gene] | CTD | PMID:28238834 | chloropicrin | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | chloropicrin results in increased expression of ELOB mRNA | CTD | PMID:26352163 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of ELOB mRNA | CTD | PMID:37019170 | cobalt dichloride | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of ELOB mRNA | CTD | PMID:19376846 | decabromodiphenyl ether | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of ELOB protein | CTD | PMID:31675489 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ELOB mRNA | CTD | PMID:17361019 | dinophysistoxin 1 | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | dinophysistoxin 1 results in increased expression of ELOB mRNA | CTD | PMID:28939011 | doxorubicin | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of ELOB mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ELOB protein | CTD | PMID:23301498 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of ELOB mRNA | CTD | PMID:30319688 | flavonoids | decreases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Flavonoids results in decreased expression of ELOB mRNA | CTD | PMID:18035473 | flutamide | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of ELOB mRNA | CTD | PMID:24136188 and PMID:24793618 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ELOB mRNA | CTD | PMID:22206623 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of ELOB mRNA | CTD | PMID:25629700 | fulvestrant | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | fulvestrant results in decreased expression of ELOB mRNA | CTD | PMID:16514628 | gentamycin | decreases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of ELOB mRNA | CTD | PMID:33387578 | glafenine | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of ELOB mRNA | CTD | PMID:24136188 | hydralazine | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of ELOB mRNA | CTD | PMID:17183730 | ivermectin | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ELOB protein | CTD | PMID:32959892 | methimazole | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of TCEB2 mRNA | CTD | PMID:30047161 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of ELOB mRNA | CTD | PMID:17942915 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ELOB mRNA] | CTD | PMID:17942915 | okadaic acid | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of ELOB mRNA | CTD | PMID:28939011 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of ELOB mRNA | CTD | PMID:34911549 | p-toluidine | decreases expression | ISO | Elob (Rattus norvegicus) | 6480464 | 4-toluidine results in decreased expression of ELOB mRNA | CTD | PMID:27638505 | quercetin | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ELOB mRNA | CTD | PMID:15309432 | raloxifene | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in decreased expression of ELOB mRNA | CTD | PMID:16514628 | rotenone | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | Rotenone results in decreased expression of ELOB mRNA | CTD | PMID:29955902 | rotenone | decreases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of ELOB protein | CTD | PMID:35544339 | silicon dioxide | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of ELOB mRNA | CTD | PMID:25351596 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ELOB protein | CTD | PMID:29044176 | sodium arsenite | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [ELOB protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of ELOB protein | CTD | PMID:28918527 | sulfadimethoxine | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of TCEB2 mRNA | CTD | PMID:30047161 | tert-butyl hydroperoxide | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of ELOB mRNA | CTD | PMID:15336504 | tetrachloroethene | decreases expression | EXP | | 6480464 | Tetrachloroethylene results in decreased expression of ELOB mRNA | CTD | PMID:28973375 | tetrachloromethane | decreases expression | ISO | Elob (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of ELOB mRNA | CTD | PMID:33387578 | triadimefon | increases expression | ISO | Elob (Rattus norvegicus) | 6480464 | triadimefon results in increased expression of TCEB2 mRNA | CTD | PMID:30047161 | tungsten | increases expression | EXP | | 6480464 | Tungsten results in increased expression of ELOB mRNA | CTD | PMID:30912803 | valproic acid | multiple interactions | ISO | ELOB (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of ELOB mRNA | CTD | PMID:17183730 | valproic acid | increases methylation | ISO | ELOB (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ELOB gene | CTD | PMID:29154799 | versicolorin A | increases expression | ISO | ELOB (Homo sapiens) | 6480464 | versicolorin A results in increased expression of ELOB mRNA | CTD | PMID:32106047 | zoledronic acid | decreases expression | ISO | ELOB (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of ELOB mRNA | CTD | PMID:24714768 | |