IGF2 (insulin-like growth factor 2 (somatomedin A))

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Keyword

Gene: IGF2 (insulin-like growth factor 2 (somatomedin A)) Homo sapiens

Symbol:

IGF2

Name:

insulin-like growth factor 2 (somatomedin A)

Description:

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

C11orf43; FLJ22066; FLJ44734; IGF-II; IGF-II; INSIGF; insulin-like growth factor 2; insulin-like growth factor II; insulin-like growth factor type 2; OTTHUMP00000011012; OTTHUMP00000011013; OTTHUMP00000011015; OTTHUMP00000011018; OTTHUMP00000011157; OTTHUMP00000011158; OTTHUMP00000220677; pp9974; PP9974; putative insulin-like growth factor II associated protein; somatomedin A; somatomedin-A

Orthologs:

Mus musculus : Igf2 (insulin-like growth factor 2) MGI
Rattus norvegicus : Igf2 (insulin-like growth factor 2)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	11	2,084,345 - 2,104,626	-	NCBI
Human Genome Assembly HuRef	11	1,940,869 - 1,961,095	-	NCBI
Human Genome Assembly GRCh37	11	2,150,347 - 2,170,833	-	NCBI
Human Genome Assembly Build 36	11	2,106,923 - 2,127,409	-	NCBI
Human Cytogenetic Map	11	p15.5		NCBI
Human Genome Assembly	11	2,110,531 - 2,116,578		NCBI