IGF2 (insulin like growth factor 2) - Rat Genome Database

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Gene: IGF2 (insulin like growth factor 2) Homo sapiens
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Symbol: IGF2
Name: insulin like growth factor 2
RGD ID: 737149
HGNC Page HGNC:5466
Description: Enables signaling receptor binding activity. Involved in positive regulation of activated T cell proliferation; positive regulation of mitotic nuclear division; and positive regulation of signal transduction. Predicted to be located in extracellular region and platelet alpha granule lumen. Predicted to be active in extracellular space. Implicated in Silver-Russell syndrome; choriocarcinoma; hepatocellular carcinoma; and rheumatoid arthritis. Biomarker of several diseases, including Lewy body dementia; acquired immunodeficiency syndrome; autoimmune disease (multiple); gastrointestinal system disease (multiple); and synucleinopathy (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C11orf43; FLJ22066; FLJ44734; GRDF; IGF-II; INSIGF; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor II; insulin-like growth factor type 2; PP9974; preptin; putative insulin-like growth factor II associated protein; somatomedin A; somatomedin-A; SRS3; T3M-11-derived growth factor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38112,129,117 - 2,149,566 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl112,129,112 - 2,158,391 (-)EnsemblGRCh38hg38GRCh38
GRCh37112,150,347 - 2,170,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,106,923 - 2,127,409 (-)NCBINCBI36Build 36hg18NCBI36
Build 34112,110,531 - 2,116,578NCBI
Celera112,186,838 - 2,207,338 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef111,940,869 - 1,961,095 (-)NCBIHuRef
CHM1_1112,148,973 - 2,169,786 (-)NCBICHM1_1
T2T-CHM13v2.0112,216,758 - 2,237,216 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acquired immunodeficiency syndrome  (IEP)
adrenocortical carcinoma  (EXP)
alcohol use disorder  (IEP)
Alcoholic Liver Diseases  (ISO)
alcoholic neuropathy  (ISO)
Alzheimer's disease  (EXP,IEP,ISO)
anemia  (EXP)
Animal Mammary Neoplasms  (ISO)
atherosclerosis  (EXP)
autistic disorder  (EXP)
Beckwith-Wiedemann syndrome  (EXP,IAGP)
bone development disease  (EXP)
Brain Hypoxia-Ischemia  (IEP)
brain infarction  (ISO)
Brain Injuries  (ISO)
breast cancer  (IEP)
choriocarcinoma  (IDA)
Chronic Hepatitis C  (IAGP)
cognitive disorder  (EXP)
Colonic Neoplasms  (EXP)
colorectal cancer  (IAGP)
Colorectal Neoplasms  (EXP)
congenital diaphragmatic hernia  (ISO)
congenital disorder of glycosylation Ia  (IEP)
delta beta-thalassemia  (IAGP)
developmental and epileptic encephalopathy  (IAGP)
Diabetic Nephropathies  (IDA,ISO)
Diaphragmatic Hernia  (EXP)
early infantile epileptic encephalopathy  (IAGP)
Embryo Loss  (ISO)
Ependymomas  (IEP)
Experimental Diabetes Mellitus  (IDA,ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
Fetal Growth Retardation  (EXP,ISO)
gastrointestinal system disease  (IEP)
genetic disease  (IAGP)
Growth Disorders  (EXP)
Hepatic Echinococcosis  (IEP)
hepatoblastoma  (EXP)
hepatocellular carcinoma  (EXP,IAGP,ISO)
hypoglycemia  (EXP)
immunodeficiency 39  (IAGP)
inflammatory bowel disease  (IEP,ISO)
Lewy body dementia  (EXP,IEP)
liver cirrhosis  (IEP)
Liver Neoplasms  (EXP)
Lung Injury  (ISO)
Memory Disorders  (EXP,ISO)
meningitis  (IEP)
Metabolic Syndrome  (ISO)
multiple sclerosis  (IEP)
multiple system atrophy  (IEP)
Neoplasm Metastasis  (ISO)
nephroblastoma  (EXP)
Nerve Degeneration  (EXP)
neuronal ceroid lipofuscinosis  (IAGP)
obesity  (EXP)
osteoarthritis  (IEP)
osteoporosis  (ISO)
Parkinson's disease  (EXP,IEP)
placenta disease  (EXP)
polyhydramnios  (EXP)
Postmenopausal Osteoporosis  (IDA)
pre-malignant neoplasm  (EXP)
rhabdomyosarcoma  (EXP)
rheumatoid arthritis  (IAGP,IEP)
Segawa Syndrome, Autosomal Recessive  (IAGP)
Silver-Russell syndrome  (EXP)
Silver-Russell Syndrome 1  (IAGP)
Silver-Russell Syndrome 3  (IAGP)
Spontaneous Abortions  (EXP)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (IEP)
ventricular septal defect  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(S)-nicotine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-ethoxyethanol  (ISO)
2-methoxyethanol  (ISO)
28-Homobrassinolide  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
adenosine  (EXP)
aflatoxin B1  (EXP)
all-trans-4-oxoretinoic acid  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-naphthoflavone  (ISO)
aluminium sulfate (anhydrous)  (EXP)
aluminium trifluoride  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
benzimidazoles  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (EXP)
benzylpenicillin  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (EXP)
budesonide  (ISO)
buta-1,3-diene  (ISO)
butanal  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP)
calciol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
carbonyl sulfide  (ISO)
carmustine  (EXP)
choline  (ISO)
chromium atom  (ISO)
cisplatin  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
corticosterone  (ISO)
cortisol  (EXP)
crocidolite asbestos  (EXP)
CU-O LINKAGE  (EXP)
Cuprizon  (ISO)
curcumin  (EXP)
dantrolene  (EXP)
DDE  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP)
estrone  (EXP)
ethanol  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP)
ethylparaben  (EXP)
fenvalerate  (ISO)
fluoxetine  (ISO)
folic acid  (EXP,ISO)
fonofos  (EXP)
fulvestrant  (EXP,ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glycidol  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
hexadecanoic acid  (EXP)
hydrogen peroxide  (ISO)
indometacin  (EXP)
iron dichloride  (EXP)
L-methionine  (ISO)
lanthanum atom  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (ISO)
lead(0)  (EXP)
lipopolysaccharide  (ISO)
LY294002  (EXP,ISO)
manganese(II) chloride  (EXP)
metformin  (EXP)
methimazole  (ISO)
monosodium L-glutamate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nickel subsulfide  (ISO)
nicotine  (ISO)
nifedipine  (EXP)
nitrofen  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (EXP)
pentanal  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylarsine oxide  (ISO)
phenylmercury acetate  (EXP)
phenytoin  (ISO)
phthalic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP)
propanal  (EXP)
propiconazole  (ISO)
quercetin  (EXP)
raloxifene  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
SB 203580  (EXP)
serpentine asbestos  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sulfadimethoxine  (ISO)
sunitinib  (EXP)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
temozolomide  (EXP)
terbufos  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetramethrin  (ISO)
thioacetamide  (ISO)
tipifarnib  (ISO)
topotecan  (ISO)
trichloroacetic acid  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vinyl carbamate  (ISO)
vorinostat  (EXP)
wortmannin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (IEA,ISO)
cellular response to mechanical stimulus  (ISO)
embryonic placenta development  (IEA,ISS)
embryonic placenta morphogenesis  (IEA,ISS)
exocrine pancreas development  (IEA,ISO)
female pregnancy  (ISO)
genomic imprinting  (TAS)
glucose metabolic process  (IEA)
in utero embryonic development  (IEA,ISS)
insulin receptor signaling pathway  (IEA,ISS,TAS)
insulin-like growth factor receptor signaling pathway  (IEA)
memory  (ISO)
negative regulation of muscle cell differentiation  (IEA,ISS)
negative regulation of natural killer cell mediated cytotoxicity  (ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISS)
ossification  (IEA)
osteoblast differentiation  (IEA)
positive regulation of activated T cell proliferation  (IBA,IDA,IEA)
positive regulation of angiogenesis  (ISO)
positive regulation of blood vessel endothelial cell migration  (ISO)
positive regulation of cell division  (IEA)
positive regulation of cell population proliferation  (IC,IDA)
positive regulation of glycogen biosynthetic process  (IEA,ISS)
positive regulation of insulin receptor signaling pathway  (IBA,IDA,IEA)
positive regulation of MAPK cascade  (IBA,IDA,IEA)
positive regulation of mitotic nuclear division  (IDA)
positive regulation of multicellular organism growth  (IEA,ISO)
positive regulation of organ growth  (IEA)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IDA,IEA,ISS)
positive regulation of skeletal muscle tissue growth  (IEA)
positive regulation of steroid hormone biosynthetic process  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IEA,ISO)
positive regulation of vascular endothelial cell proliferation  (IBA,IEA)
regulation of DNA-templated transcription  (NAS)
regulation of muscle cell differentiation  (IBA,IEA,ISS)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to nicotine  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)
spongiotrophoblast cell proliferation  (IEA)
striated muscle cell differentiation  (IEA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal cardiovascular system morphology  (IAGP)
Abnormal external genitalia  (IAGP)
Abnormal scrotum morphology  (IAGP)
Abnormality of the cardiovascular system  (IAGP)
Abnormality of the dentition  (IAGP)
Abnormality of the ureter  (IAGP)
Accelerated skeletal maturation  (IAGP)
Adrenocortical carcinoma  (IAGP)
Adrenocortical cytomegaly  (IAGP)
Ambiguous genitalia  (IAGP)
Antecubital pterygium  (IAGP)
Asthma  (IAGP)
Asymmetric growth  (IAGP)
Asymmetry of the thorax  (IAGP)
Attention deficit hyperactivity disorder  (IAGP)
Autosomal dominant inheritance  (IAGP)
Bifid scrotum  (IAGP)
Blue sclerae  (IAGP)
Cafe-au-lait spot  (IAGP)
Cardiomegaly  (IAGP)
Cardiomyopathy  (IAGP)
Cleft palate  (IAGP)
Clinodactyly of the 5th finger  (IAGP)
Coarse facial features  (IAGP)
Colon cancer  (IAGP)
Congenital onset  (IAGP)
Congenital posterior urethral valve  (IAGP)
Craniofacial disproportion  (IAGP)
Craniopharyngioma  (IAGP)
Cryptorchidism  (IAGP)
Dandy-Walker malformation  (IAGP)
Decreased body weight  (IAGP)
Decreased fetal movement  (IAGP)
Decreased response to growth hormone stimulation test  (IAGP)
Delayed closure of the anterior fontanelle  (IAGP)
Delayed cranial suture closure  (IAGP)
Delayed skeletal maturation  (IAGP)
Delayed speech and language development  (IAGP)
Dental crowding  (IAGP)
Diastasis recti  (IAGP)
Downturned corners of mouth  (IAGP)
Dysmenorrhea  (IAGP)
Ectrodactyly  (IAGP)
Elbow contracture  (IAGP)
Enlarged kidney  (IAGP)
Facial asymmetry  (IAGP)
Failure to thrive  (IAGP)
Fasting hypoglycemia  (IAGP)
Feeding difficulties  (IAGP)
Feeding difficulties in infancy  (IAGP)
Frontal bossing  (IAGP)
Global developmental delay  (IAGP)
Gonadoblastoma  (IAGP)
Hemihypertrophy  (IAGP)
Hepatoblastoma  (IAGP)
Hepatocellular carcinoma  (IAGP)
Hepatomegaly  (IAGP)
High palate  (IAGP)
Hyperhidrosis  (IAGP)
Hypoglycemia  (IAGP)
Hypoplastic fingernail  (IAGP)
Hypospadias  (IAGP)
Hypothyroidism  (IAGP)
Hypotonia  (IAGP)
Impaired pain sensation  (IAGP)
Increased body mass index  (IAGP)
Infantile muscular hypotonia  (IAGP)
Inguinal hernia  (IAGP)
Intellectual disability  (IAGP)
Intellectual disability, mild  (IAGP)
Intrauterine growth retardation  (IAGP)
Large fontanelles  (IAGP)
Low-set ears  (IAGP)
Lower limb asymmetry  (IAGP)
Macroglossia  (IAGP)
Melanocytic nevus  (IAGP)
Micrognathia  (IAGP)
Microphallus  (IAGP)
Midface retrusion  (IAGP)
Motor delay  (IAGP)
Myelomeningocele  (IAGP)
Neonatal hypoglycemia  (IAGP)
Nephroblastoma  (IAGP)
Nephrocalcinosis  (IAGP)
Nephrolithiasis  (IAGP)
Nevus flammeus  (IAGP)
Oligohydramnios  (IAGP)
Omphalocele  (IAGP)
Overgrowth  (IAGP)
Overgrowth of external genitalia  (IAGP)
Pancreatic hyperplasia  (IAGP)
Patent ductus arteriosus  (IAGP)
Penoscrotal hypospadias  (IAGP)
Placental mesenchymal dysplasia  (IAGP)
Polydactyly  (IAGP)
Posterior helix pit  (IAGP)
Postnatal growth retardation  (IAGP)
Prominent forehead  (IAGP)
Prominent metopic ridge  (IAGP)
Prominent occiput  (IAGP)
Proptosis  (IAGP)
Protruding ear  (IAGP)
Relative macrocephaly  (IAGP)
Renal cortical cysts  (IAGP)
Retrognathia  (IAGP)
Scoliosis  (IAGP)
Seizure  (IAGP)
Severe intrauterine growth retardation  (IAGP)
Short 5th finger  (IAGP)
Short chin  (IAGP)
Short distal phalanx of the 5th finger  (IAGP)
Short middle phalanx of the 5th finger  (IAGP)
Short stature  (IAGP)
Small for gestational age  (IAGP)
Small hand  (IAGP)
Small placenta  (IAGP)
Specific learning disability  (IAGP)
Sporadic  (IAGP)
Syndactyly  (IAGP)
Testicular seminoma  (IAGP)
Triangular face  (IAGP)
Typified by somatic mosaicism  (IAGP)
Umbilical hernia  (IAGP)
Unilateral cryptorchidism  (IAGP)
Upper limb asymmetry  (IAGP)
Urethral valve  (IAGP)
Vesicoureteral reflux  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Oleic acid ameliorates amyloidosis in cellular and mouse models of Alzheimer's disease. Amtul Z, etal., Brain Pathol. 2011 May;21(3):321-9. doi: 10.1111/j.1750-3639.2010.00449.x. Epub 2010 Nov 11.
2. Uptake of circulating insulin-like growth factor-I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rat brain. Armstrong CS, etal., J Neurosci Res. 2000 Mar 1;59(5):649-60.
3. [Changes of serum and cerebrospinal fluid insulin-like growth factor-II levels in neonates with hypoxic-ischemic encephalopathy]. Bai B, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2006 Jun;8(3):187-90.
4. Gastrointestinal inflammation and the circulating IGF system in humans. Baricevic I, etal., Horm Metab Res. 2006 Jan;38(1):22-7.
5. Insulin-like growth factor II is induced during wound repair following hypoxic-ischemic injury in the developing rat brain. Beilharz EJ, etal., Brain Res Mol Brain Res. 1995 Mar;29(1):81-91.
6. In utero radiation-induced changes in growth factor levels in the developing rat brain. Benekou A, etal., Int J Radiat Biol. 2001 Jan;77(1):83-93.
7. Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto-Kakizaki rat model of type 2 diabetes. Calderari S, etal., Diabetologia. 2007 Jul;50(7):1463-71. Epub 2007 May 3.
8. Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis. Conover CA, etal., Growth Horm IGF Res. 2002 Jun;12(3):178-83.
9. The insulin-like growth factor axis in children with inflammatory bowel disease. Corkins MR, etal., J Pediatr Gastroenterol Nutr. 2003 Feb;36(2):228-34.
10. Various components of the insulin-like growth factor system in tumor tissue, cerebrospinal fluid and peripheral blood of pediatric medulloblastoma and ependymoma patients. de Bont JM, etal., Int J Cancer. 2008 Aug 1;123(3):594-600.
11. Insulin resistance in experimental alcohol-induced liver disease. de la Monte SM, etal., J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e477-86. Epub 2008 May 26.
12. Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes. Devedjian JC, etal., J Clin Invest. 2000 Mar;105(6):731-40.
13. IGF-II regulates metastatic properties of choriocarcinoma cells through the activation of the insulin receptor. Diaz LE, etal., Mol Hum Reprod. 2007 Aug;13(8):567-76. Epub 2007 Jun 6.
14. Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions. Duan C and Xu Q, Gen Comp Endocrinol. 2005 May 15;142(1-2):44-52. Epub 2005 Feb 5.
15. The insulin-like growth factor system and markers of inflammation in adult patients with inflammatory bowel disease. Eivindson M, etal., Horm Res. 2005;64(1):9-15. Epub 2005 Jul 25.
16. Elevated free IGF2 levels in localized, early-stage breast cancer in women. Espelund U, etal., Eur J Endocrinol. 2008 Nov;159(5):595-601. Epub 2008 Aug 21.
17. Comparative effects of probiotics, prebiotics, and synbiotics on growth factors in the large bowel in a rat model of formula-induced bowel inflammation. Fordjour L, etal., J Pediatr Gastroenterol Nutr. 2010 Oct;51(4):507-13.
18. Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males. Gaunt TR, etal., Hum Mol Genet. 2001 Jul 1;10(14):1491-501.
19. NMDA receptor mediated changes in IGF-II gene expression in the rat brain after injury and the possible role of nitric oxide. Giannakopoulou M, etal., Neuropathol Appl Neurobiol. 2000 Dec;26(6):513-21.
20. A simple in silico strategy identifies candidate biomarkers for the diagnosis of liver fibrosis in morbidly obese subjects. Giraudi PJ, etal., Liver Int. 2018 Jan;38(1):155-163. doi: 10.1111/liv.13505. Epub 2017 Jul 21.
21. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
22. Insulin-like growth factors and binding proteins in multiple sclerosis plaques. Gveric D, etal., Neuropathol Appl Neurobiol. 1999 Jun;25(3):215-25.
23. Tissue-specific regulation of insulin-like growth factors and insulin-like growth factor binding proteins in male diabetic rats in vivo and in vitro. Han HJ, etal., Clin Exp Pharmacol Physiol. 2006 Dec;33(12):1172-9.
24. The insulin-like growth factor system in human immunodeficiency virus infection: relations to immunological parameters, disease progression, and antiretroviral therapy. Helle SI, etal., J Clin Endocrinol Metab. 2001 Jan;86(1):227-33.
25. Changes in cerebrospinal fluid and blood plasma levels of IGF-II and its binding proteins in Alzheimer's disease: an observational study. Hertze J, etal., BMC Neurol. 2014 Apr 1;14:64. doi: 10.1186/1471-2377-14-64.
26. Insulin-Like growth factor-II (IGF-II) prevents proinflammatory cytokine-induced apoptosis and significantly improves islet survival after transplantation. Hughes A, etal., Transplantation. 2013 Mar 15;95(5):671-8. doi: 10.1097/TP.0b013e31827fa453.
27. Gene Expression Profiling Distinguishes Between Spontaneous and Radiation-induced Rat Mammary Carcinomas. Imaoka T, etal., J Radiat Res (Tokyo). 2008 Apr 16;.
28. Abnormal Igf2 gene in Prague hereditary hypertriglyceridemic rats: its relation to blood pressure and plasma lipids. Kadlecova M, etal., Mol Cell Biochem. 2008 Jul;314(1-2):37-43. Epub 2008 Apr 17.
29. Thymic expression of insulin-related genes in an animal model of autoimmune type 1 diabetes. Kecha-Kamoun O, etal., Diabetes Metab Res Rev. 2001 Mar-Apr;17(2):146-52.
30. IGF2 polymorphisms are associated with hepatitis B virus clearance and hepatocellular carcinoma. Kim YJ, etal., Biochem Biophys Res Commun. 2006 Jul 21;346(1):38-44. doi: 10.1016/j.bbrc.2006.05.080. Epub 2006 May 24.
31. Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia. Kutasy B, etal., Pediatr Surg Int. 2014 Feb;30(2):137-42. doi: 10.1007/s00383-013-3449-7.
32. Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease. Lester-Coll N, etal., J Alzheimers Dis. 2006 Mar;9(1):13-33.
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42. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
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47. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
48. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
49. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
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Additional References at PubMed
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Genomics

Comparative Map Data
IGF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38112,129,117 - 2,149,566 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl112,129,112 - 2,158,391 (-)EnsemblGRCh38hg38GRCh38
GRCh37112,150,347 - 2,170,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36112,106,923 - 2,127,409 (-)NCBINCBI36Build 36hg18NCBI36
Build 34112,110,531 - 2,116,578NCBI
Celera112,186,838 - 2,207,338 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef111,940,869 - 1,961,095 (-)NCBIHuRef
CHM1_1112,148,973 - 2,169,786 (-)NCBICHM1_1
T2T-CHM13v2.0112,216,758 - 2,237,216 (-)NCBIT2T-CHM13v2.0
Igf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397142,204,505 - 142,220,566 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7142,204,503 - 142,220,553 (-)EnsemblGRCm39 Ensembl
GRCm387142,650,768 - 142,666,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7142,650,766 - 142,666,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv377149,836,673 - 149,846,940 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367142,460,158 - 142,468,879 (-)NCBIMGSCv36mm8
Celera7142,407,105 - 142,417,364 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.99NCBI
Igf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81207,243,873 - 207,261,263 (-)NCBIGRCr8
mRatBN7.21197,814,409 - 197,831,802 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1197,814,410 - 197,823,018 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1206,187,237 - 206,197,377 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,273,145 - 213,283,290 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01205,947,308 - 205,957,453 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01215,828,102 - 215,839,081 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1215,828,102 - 215,846,911 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01222,722,921 - 222,733,868 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41202,906,624 - 202,915,231 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11203,094,689 - 203,103,297 (-)NCBI
Celera1195,432,460 - 195,442,561 (-)NCBICelera
Cytogenetic Map1q41NCBI
Igf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542213,880,471 - 13,888,566 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542213,880,525 - 13,907,963 (-)NCBIChiLan1.0ChiLan1.0
IGF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v294,555,470 - 4,584,748 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1113,767,218 - 3,777,154 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0112,170,190 - 2,199,442 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1112,202,764 - 2,228,890 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl112,202,743 - 2,228,890 (-)Ensemblpanpan1.1panPan2
IGF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11846,294,036 - 46,311,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1846,294,019 - 46,311,982 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1844,906,773 - 44,921,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01846,973,499 - 46,991,455 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1846,973,482 - 47,002,253 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11846,425,198 - 46,440,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01846,005,530 - 46,020,544 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01846,751,952 - 46,766,988 (-)NCBIUU_Cfam_GSD_1.0
Igf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049471,719,158 - 1,727,419 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936816972,282 - 979,167 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936816972,902 - 981,232 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.121,469,183 - 1,496,417 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap2pNCBI
IGF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111,937,414 - 1,951,238 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11,936,830 - 1,945,388 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603899,135,565 - 99,144,253 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476714,969,866 - 14,979,026 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476714,969,977 - 14,997,577 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IGF2
128 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001042376.3(INS-IGF2):c.187+2146A>T single nucleotide variant INSULIN-LIKE GROWTH FACTOR II POLYMORPHISM [RCV000015869] Chr11:11p15.5 benign
NM_001007139.6(IGF2):c.-248-73= single nucleotide variant INSULIN-LIKE GROWTH FACTOR II POLYMORPHISM [RCV000015870] Chr11:2147880 [GRCh38]
Chr11:2169110 [GRCh37]
Chr11:11p15.5
benign
NM_001007139.6(IGF2):c.*1958= single nucleotide variant INSULIN-LIKE GROWTH FACTOR II POLYMORPHISM [RCV000015871] Chr11:11p15.5 benign
GRCh38/hg38 11p15.5-15.4(chr11:196966-3377077)x3 copy number gain See cases [RCV000050947] Chr11:196966..3377077 [GRCh38]
Chr11:196966..3398307 [GRCh37]
Chr11:186966..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-4435344)x3 copy number gain See cases [RCV000050927] Chr11:196966..4435344 [GRCh38]
Chr11:196966..4456574 [GRCh37]
Chr11:186966..4413150 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:218365-3377077)x3 copy number gain See cases [RCV000053614] Chr11:218365..3377077 [GRCh38]
Chr11:218365..3398307 [GRCh37]
Chr11:208365..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3624139)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|See cases [RCV000053592] Chr11:196966..3624139 [GRCh38]
Chr11:196966..3645369 [GRCh37]
Chr11:186966..3601945 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
NM_001042376.2(INS-IGF2):c.*488G>A single nucleotide variant Malignant melanoma [RCV000069292] Chr11:2146304 [GRCh38]
Chr11:2167534 [GRCh37]
Chr11:2124110 [NCBI36]
Chr11:11p15.5
not provided
NM_000612.6(IGF2):c.520_521insC (p.Glu174fs) insertion Colorectal cancer [RCV001293830] Chr11:2133009..2133010 [GRCh38]
Chr11:2154239..2154240 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1975511-2888695)x3 copy number gain See cases [RCV000136112] Chr11:1975511..2888695 [GRCh38]
Chr11:1996741..2909925 [GRCh37]
Chr11:1953317..2866501 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:1537379-3360769)x3 copy number gain See cases [RCV000136847] Chr11:1537379..3360769 [GRCh38]
Chr11:1558609..3381999 [GRCh37]
Chr11:1515185..3338575 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:1975511-2138446)x3 copy number gain See cases [RCV000137018] Chr11:1975511..2138446 [GRCh38]
Chr11:1996741..2159676 [GRCh37]
Chr11:1953317..2116252 [NCBI36]
Chr11:11p15.5
benign
GRCh38/hg38 11p15.5-15.4(chr11:1975511-3624139)x1 copy number loss See cases [RCV000137066] Chr11:1975511..3624139 [GRCh38]
Chr11:1996741..3645369 [GRCh37]
Chr11:1953317..3601945 [NCBI36]
Chr11:11p15.5-15.4
uncertain significance
GRCh38/hg38 11p15.5(chr11:2149352-2467542)x3 copy number gain See cases [RCV000137405] Chr11:2149352..2467542 [GRCh38]
Chr11:2170582..2488772 [GRCh37]
Chr11:2127158..2445348 [NCBI36]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5(chr11:2052381-2138446)x3 copy number gain See cases [RCV000137157] Chr11:2052381..2138446 [GRCh38]
Chr11:2073611..2159676 [GRCh37]
Chr11:2030187..2116252 [NCBI36]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:2127344-2159430)x3 copy number gain See cases [RCV000141243] Chr11:2127344..2159430 [GRCh38]
Chr11:2148574..2180660 [GRCh37]
Chr11:2105150..2137236 [NCBI36]
Chr11:11p15.5
uncertain significance
NM_001127598.3(IGF2):c.82G>A (p.Gly28Arg) single nucleotide variant not specified [RCV000203020] Chr11:2140215 [GRCh38]
Chr11:2161445 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.4(chr11:1132899-3213923)x1 copy number loss See cases [RCV000142464] Chr11:1132899..3213923 [GRCh38]
Chr11:1126807..3235153 [GRCh37]
Chr11:1116807..3191729 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196855-5321874)x3 copy number gain See cases [RCV000142890] Chr11:196855..5321874 [GRCh38]
Chr11:196855..5343104 [GRCh37]
Chr11:186855..5299680 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:2106943-2565669)x3 copy number gain See cases [RCV000143587] Chr11:2106943..2565669 [GRCh38]
Chr11:2128173..2586899 [GRCh37]
Chr11:2084749..2543475 [NCBI36]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.23C>A (p.Ser8Ter) single nucleotide variant Silver-Russell syndrome 3 [RCV000186560] Chr11:2135501 [GRCh38]
Chr11:2156731 [GRCh37]
Chr11:11p15.5
pathogenic|likely pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:193187-5291338)x3 copy number gain See cases [RCV000446036] Chr11:193187..5291338 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.518dup (p.Glu174fs) duplication not provided [RCV000520721] Chr11:2133011..2133012 [GRCh38]
Chr11:2154241..2154242 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5(chr11:1621232-2228572) copy number gain Beckwith-Wiedemann syndrome [RCV002280763] Chr11:1621232..2228572 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.472del (p.Pro157_Leu158insTer) deletion not provided [RCV000598672] Chr11:2133058 [GRCh38]
Chr11:2154288 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.211T>C (p.Cys71Arg) single nucleotide variant not provided [RCV000731499] Chr11:2133612 [GRCh38]
Chr11:2154842 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.99C>A (p.Cys33Ter) single nucleotide variant not provided [RCV000412860] Chr11:2135425 [GRCh38]
Chr11:2156655 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.97T>C (p.Cys33Arg) single nucleotide variant not provided [RCV000414320] Chr11:2135427 [GRCh38]
Chr11:2156657 [GRCh37]
Chr11:11p15.5
likely pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-6644927)x3 copy number gain See cases [RCV000449417] Chr11:230615..6644927 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.78C>G (p.Tyr26Ter) single nucleotide variant Silver-Russell syndrome 1 [RCV000491853]|not provided [RCV000479354] Chr11:2135446 [GRCh38]
Chr11:2156676 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3 copy number gain See cases [RCV000511561] Chr11:230615..37698540 [GRCh37]
Chr11:11p15.5-12
pathogenic
NM_000612.6(IGF2):c.157+1_157+2insGC insertion Silver-Russell syndrome 1 [RCV000490875] Chr11:2135365..2135366 [GRCh38]
Chr11:2156595..2156596 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136) copy number gain Silver-Russell syndrome 1 [RCV000767567] Chr11:193146..12643136 [GRCh37]
Chr11:11p15.5-15.3
pathogenic
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3 copy number gain See cases [RCV000512225] Chr11:230615..25584362 [GRCh37]
Chr11:11p15.5-14.3
pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3 copy number gain See cases [RCV000512477] Chr11:230615..31995219 [GRCh37]
Chr11:11p15.5-13
pathogenic
GRCh37/hg19 11p15.5(chr11:1690968-2277648)x3 copy number gain See cases [RCV000512345] Chr11:1690968..2277648 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3 copy number gain not provided [RCV000683369] Chr11:230615..9704511 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3 copy number gain not provided [RCV000683372] Chr11:230615..17099213 [GRCh37]
Chr11:11p15.5-15.1
pathogenic
NM_001042376.3(INS-IGF2):c.581G>A (p.Arg194Gln) single nucleotide variant Inborn genetic diseases [RCV003183429] Chr11:2147634 [GRCh38]
Chr11:2168864 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5(chr11:2101692-2150444)x1 copy number loss not provided [RCV000737384] Chr11:2101692..2150444 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.96G>C (p.Leu32=) single nucleotide variant not provided [RCV000982469] Chr11:2135428 [GRCh38]
Chr11:2156658 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.129C>T (p.Phe43=) single nucleotide variant not provided [RCV000922798] Chr11:2135395 [GRCh38]
Chr11:2156625 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.444G>A (p.Ala148=) single nucleotide variant not provided [RCV000902594] Chr11:2133086 [GRCh38]
Chr11:2154316 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.234C>G (p.Ala78=) single nucleotide variant not provided [RCV000883318] Chr11:2133589 [GRCh38]
Chr11:2154819 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.381C>T (p.Arg127=) single nucleotide variant IGF2-related condition [RCV003950615]|not provided [RCV000903609] Chr11:2133149 [GRCh38]
Chr11:2154379 [GRCh37]
Chr11:11p15.5
benign|likely benign
NM_000612.6(IGF2):c.480T>C (p.Ala160=) single nucleotide variant IGF2-related condition [RCV003943010]|not provided [RCV000948858] Chr11:2133050 [GRCh38]
Chr11:2154280 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.261C>T (p.Pro87=) single nucleotide variant not provided [RCV000902960] Chr11:2133562 [GRCh38]
Chr11:2154792 [GRCh37]
Chr11:11p15.5
likely benign
NM_001127598.3(IGF2):c.97C>T (p.Gln33Ter) single nucleotide variant Inborn genetic diseases [RCV002539309]|not provided [RCV000882263] Chr11:2140200 [GRCh38]
Chr11:2161430 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.240G>A (p.Leu80=) single nucleotide variant not provided [RCV000965162] Chr11:2133583 [GRCh38]
Chr11:2154813 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.380G>T (p.Arg127Leu) single nucleotide variant not provided [RCV000801891] Chr11:2133150 [GRCh38]
Chr11:2154380 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3 copy number gain not provided [RCV001006372] Chr11:235934..33826995 [GRCh37]
Chr11:11p15.5-13
pathogenic
NC_000011.9:g.(?_532616)_(2906985_?)dup duplication Neuronal ceroid lipofuscinosis [RCV001032557] Chr11:532616..2906985 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
NM_000612.6(IGF2):c.412C>G (p.Arg138Gly) single nucleotide variant not provided [RCV003106383] Chr11:2133118 [GRCh38]
Chr11:2154348 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.490C>T (p.Gln164Ter) single nucleotide variant not provided [RCV001559627] Chr11:2133040 [GRCh38]
Chr11:2154270 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_001127598.3(IGF2):c.90C>T (p.Thr30=) single nucleotide variant not provided [RCV000886807] Chr11:2140207 [GRCh38]
Chr11:2161437 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.467G>A (p.Arg156His) single nucleotide variant not provided [RCV000886219] Chr11:2133063 [GRCh38]
Chr11:2154293 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.279C>T (p.Asp93=) single nucleotide variant not provided [RCV000932208] Chr11:2133544 [GRCh38]
Chr11:2154774 [GRCh37]
Chr11:11p15.5
likely benign
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.163C>T (p.Pro55Ser) single nucleotide variant not provided [RCV003234308] Chr11:2133660 [GRCh38]
Chr11:2154890 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.100G>A (p.Gly34Ser) single nucleotide variant not provided [RCV001546589]|not specified [RCV002300547] Chr11:2135424 [GRCh38]
Chr11:2156654 [GRCh37]
Chr11:11p15.5
pathogenic|uncertain significance
NM_000612.6(IGF2):c.157+3A>C single nucleotide variant Silver-Russell syndrome 3 [RCV001174515] Chr11:2135364 [GRCh38]
Chr11:2156594 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.101G>A (p.Gly34Asp) single nucleotide variant Silver-Russell syndrome 3 [RCV001174514]|not provided [RCV001558444] Chr11:2135423 [GRCh38]
Chr11:2156653 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.195del (p.Ile66fs) deletion Silver-Russell syndrome 3 [RCV001174516] Chr11:2133628 [GRCh38]
Chr11:2154858 [GRCh37]
Chr11:11p15.5
pathogenic|likely pathogenic
NM_000612.6(IGF2):c.110_117delinsAGGTAA (p.Leu37fs) indel Silver-Russell syndrome 3 [RCV001174513] Chr11:2135407..2135414 [GRCh38]
Chr11:2156637..2156644 [GRCh37]
Chr11:11p15.5
pathogenic
NM_001042376.3(INS-IGF2):c.337A>C (p.Thr113Pro) single nucleotide variant not provided [RCV001196443] Chr11:2149196 [GRCh38]
Chr11:2170426 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.27del (p.Met9fs) deletion Silver-Russell syndrome 3 [RCV001253454] Chr11:2135497 [GRCh38]
Chr11:2156727 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-4851537)x3 copy number gain See cases [RCV001263059] Chr11:230615..4851537 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.100G>T (p.Gly34Cys) single nucleotide variant Beckwith-Wiedemann syndrome [RCV002491857]|Silver-Russell syndrome 3 [RCV001253240] Chr11:2135424 [GRCh38]
Chr11:2156654 [GRCh37]
Chr11:11p15.5
likely pathogenic
GRCh37/hg19 11p15.5(chr11:1436158-2321134)x3 copy number gain not provided [RCV001259591] Chr11:1436158..2321134 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3 copy number gain Silver-Russell syndrome 1 [RCV001263222] Chr11:210300..8664358 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Autosomal recessive DOPA responsive dystonia [RCV001301561]|Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001127598.3(IGF2):c.162G>C (p.Gln54His) single nucleotide variant not provided [RCV001358206] Chr11:2140135 [GRCh38]
Chr11:2161365 [GRCh37]
Chr11:11p15.5
uncertain significance
NC_000011.9:g.(?_298501)_(4113028_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001316682] Chr11:298501..4113028 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
NM_000612.6(IGF2):c.2T>C (p.Met1Thr) single nucleotide variant not provided [RCV001366321] Chr11:2135522 [GRCh38]
Chr11:2156752 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:10701-5080415)x2 copy number gain See cases [RCV001310286] Chr11:10701..5080415 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.227del (p.Asp76fs) deletion not provided [RCV001682665] Chr11:2133596 [GRCh38]
Chr11:2154826 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_000612.6(IGF2):c.59C>A (p.Ser20Ter) single nucleotide variant Silver-Russell syndrome 3 [RCV002226891] Chr11:2135465 [GRCh38]
Chr11:2156695 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_001127598.3(IGF2):c.34G>C (p.Ala12Pro) single nucleotide variant not provided [RCV001764851] Chr11:2140263 [GRCh38]
Chr11:2161493 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.199G>A (p.Val67Ile) single nucleotide variant Silver-Russell syndrome 3 [RCV001797006] Chr11:2133624 [GRCh38]
Chr11:2154854 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.212G>A (p.Cys71Tyr) single nucleotide variant not provided [RCV001913774] Chr11:2133611 [GRCh38]
Chr11:2154841 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:230615-5525355)x3 copy number gain not provided [RCV001825269] Chr11:230615..5525355 [GRCh37]
Chr11:11p15.5-15.4
not provided
GRCh37/hg19 11p15.5(chr11:1719815-2321109)x3 copy number gain not provided [RCV001827983] Chr11:1719815..2321109 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_000612.6(IGF2):c.257C>A (p.Thr86Asn) single nucleotide variant not provided [RCV001912975] Chr11:2133566 [GRCh38]
Chr11:2154796 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.59C>T (p.Ser20Leu) single nucleotide variant not provided [RCV001951905] Chr11:2135465 [GRCh38]
Chr11:2156695 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.466C>T (p.Arg156Cys) single nucleotide variant Inborn genetic diseases [RCV002545884]|not provided [RCV001904487] Chr11:2133064 [GRCh38]
Chr11:2154294 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.245C>T (p.Thr82Met) single nucleotide variant not provided [RCV001999531] Chr11:2133578 [GRCh38]
Chr11:2154808 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.307-3C>T single nucleotide variant not provided [RCV001900294] Chr11:2133226 [GRCh38]
Chr11:2154456 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.190C>T (p.Arg64Cys) single nucleotide variant not provided [RCV001998666] Chr11:2133633 [GRCh38]
Chr11:2154863 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.504C>T (p.His168=) single nucleotide variant not provided [RCV002129892] Chr11:2133026 [GRCh38]
Chr11:2154256 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.30G>A (p.Leu10=) single nucleotide variant not provided [RCV002149812] Chr11:2135494 [GRCh38]
Chr11:2156724 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.438C>A (p.Leu146=) single nucleotide variant not provided [RCV002126713] Chr11:2133092 [GRCh38]
Chr11:2154322 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.270C>T (p.Ser90=) single nucleotide variant not provided [RCV002117652] Chr11:2133553 [GRCh38]
Chr11:2154783 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.441G>A (p.Glu147=) single nucleotide variant not provided [RCV002122753] Chr11:2133089 [GRCh38]
Chr11:2154319 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.303T>C (p.Leu101=) single nucleotide variant not provided [RCV002155588] Chr11:2133520 [GRCh38]
Chr11:2154750 [GRCh37]
Chr11:11p15.5
likely benign
NC_000011.9:g.(?_1278740)_(2906719_?)dup duplication Autosomal recessive DOPA responsive dystonia [RCV003113999] Chr11:1278740..2906719 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
NC_000011.9:g.(?_721044)_(3988932_?)dup duplication not provided [RCV003113442] Chr11:721044..3988932 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
NM_000612.6(IGF2):c.-6-2A>T single nucleotide variant Silver-Russell syndrome 3 [RCV002290217] Chr11:2135531 [GRCh38]
Chr11:2156761 [GRCh37]
Chr11:11p15.5
pathogenic
NC_000011.10:g.(499700_4999400)_(5279346_5279697)del deletion Thalassemia, gamma-delta-beta [RCV000015529] Chr11:4999400..5279346 [GRCh38]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-14.2(chr11:230615-26881146)x3 copy number gain See cases [RCV002286351] Chr11:230615..26881146 [GRCh37]
Chr11:11p15.5-14.2
pathogenic
NM_000612.6(IGF2):c.106G>T (p.Glu36Ter) single nucleotide variant See cases [RCV003156171]|not provided [RCV003689044] Chr11:2135418 [GRCh38]
Chr11:2156648 [GRCh37]
Chr11:11p15.5
pathogenic|likely pathogenic
NM_000612.6(IGF2):c.106del (p.Glu36fs) deletion Silver-Russell syndrome 3 [RCV003148454] Chr11:2135418 [GRCh38]
Chr11:2156648 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_001042376.3(INS-IGF2):c.584C>G (p.Pro195Arg) single nucleotide variant Inborn genetic diseases [RCV002902078] Chr11:2147631 [GRCh38]
Chr11:2168861 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5(chr11:461373-2157956)x4 copy number gain not provided [RCV002473945] Chr11:461373..2157956 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230616-8250724)x3 copy number gain not provided [RCV002472435] Chr11:230616..8250724 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_001042376.3(INS-IGF2):c.325A>G (p.Arg109Gly) single nucleotide variant Inborn genetic diseases [RCV002859926] Chr11:2149208 [GRCh38]
Chr11:2170438 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.518C>T (p.Pro173Leu) single nucleotide variant Inborn genetic diseases [RCV002902872] Chr11:2133012 [GRCh38]
Chr11:2154242 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.416G>T (p.Gly139Val) single nucleotide variant not provided [RCV002617075] Chr11:2133114 [GRCh38]
Chr11:2154344 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.386G>T (p.Gly129Val) single nucleotide variant not provided [RCV002726247] Chr11:2133144 [GRCh38]
Chr11:2154374 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001042376.3(INS-IGF2):c.460C>G (p.Gln154Glu) single nucleotide variant Inborn genetic diseases [RCV002733781] Chr11:2147755 [GRCh38]
Chr11:2168985 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.503A>C (p.His168Pro) single nucleotide variant Inborn genetic diseases [RCV002974670] Chr11:2133027 [GRCh38]
Chr11:2154257 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.138G>T (p.Gly46=) single nucleotide variant not provided [RCV002975453] Chr11:2135386 [GRCh38]
Chr11:2156616 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.505G>C (p.Gly169Arg) single nucleotide variant Inborn genetic diseases [RCV002990301] Chr11:2133025 [GRCh38]
Chr11:2154255 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.21G>T (p.Lys7Asn) single nucleotide variant Inborn genetic diseases [RCV002991980]|not provided [RCV003561147] Chr11:2135503 [GRCh38]
Chr11:2156733 [GRCh37]
Chr11:11p15.5
likely benign|uncertain significance
NM_000612.6(IGF2):c.439G>A (p.Glu147Lys) single nucleotide variant not provided [RCV002614973] Chr11:2133091 [GRCh38]
Chr11:2154321 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.158-20_158-17del deletion not provided [RCV003033828] Chr11:2133682..2133685 [GRCh38]
Chr11:2154912..2154915 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.78C>T (p.Tyr26=) single nucleotide variant not provided [RCV003020758] Chr11:2135446 [GRCh38]
Chr11:2156676 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.100G>C (p.Gly34Arg) single nucleotide variant Inborn genetic diseases [RCV002692236] Chr11:2135424 [GRCh38]
Chr11:2156654 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.-2C>G single nucleotide variant Inborn genetic diseases [RCV002844249] Chr11:2135525 [GRCh38]
Chr11:2156755 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.158-19T>A single nucleotide variant not provided [RCV002706066] Chr11:2133684 [GRCh38]
Chr11:2154914 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.495C>G (p.Asp165Glu) single nucleotide variant Inborn genetic diseases [RCV003008914]|not provided [RCV002999304] Chr11:2133035 [GRCh38]
Chr11:2154265 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.439G>C (p.Glu147Gln) single nucleotide variant not provided [RCV002591496] Chr11:2133091 [GRCh38]
Chr11:2154321 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.306G>A (p.Pro102=) single nucleotide variant not provided [RCV002736751] Chr11:2133517 [GRCh38]
Chr11:2154747 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.505G>T (p.Gly169Trp) single nucleotide variant Inborn genetic diseases [RCV002765117]|not provided [RCV003778646] Chr11:2133025 [GRCh38]
Chr11:2154255 [GRCh37]
Chr11:11p15.5
likely benign|uncertain significance
NM_000612.6(IGF2):c.89_98del (p.Glu30fs) deletion not provided [RCV003058118] Chr11:2135426..2135435 [GRCh38]
Chr11:2156656..2156665 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.285G>A (p.Ser95=) single nucleotide variant not provided [RCV002572333] Chr11:2133538 [GRCh38]
Chr11:2154768 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.99C>T (p.Cys33=) single nucleotide variant IGF2-related condition [RCV003916512]|not provided [RCV002700316] Chr11:2135425 [GRCh38]
Chr11:2156655 [GRCh37]
Chr11:11p15.5
likely benign
NM_001042376.3(INS-IGF2):c.410G>A (p.Gly137Asp) single nucleotide variant Inborn genetic diseases [RCV002919305] Chr11:2147805 [GRCh38]
Chr11:2169035 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001042376.3(INS-IGF2):c.352G>C (p.Val118Leu) single nucleotide variant Inborn genetic diseases [RCV002792362] Chr11:2149181 [GRCh38]
Chr11:2170411 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.20A>C (p.Lys7Thr) single nucleotide variant not provided [RCV002632007] Chr11:2135504 [GRCh38]
Chr11:2156734 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.144C>T (p.Arg48=) single nucleotide variant not provided [RCV002770478] Chr11:2135380 [GRCh38]
Chr11:2156610 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.370C>G (p.Gln124Glu) single nucleotide variant not provided [RCV003046015] Chr11:2133160 [GRCh38]
Chr11:2154390 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001042376.3(INS-IGF2):c.212C>G (p.Ser71Cys) single nucleotide variant Inborn genetic diseases [RCV002807912] Chr11:2149321 [GRCh38]
Chr11:2170551 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.165C>T (p.Pro55=) single nucleotide variant not provided [RCV002581329] Chr11:2133658 [GRCh38]
Chr11:2154888 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.499G>T (p.Ala167Ser) single nucleotide variant Inborn genetic diseases [RCV002678469]|not provided [RCV003777635] Chr11:2133031 [GRCh38]
Chr11:2154261 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.421G>A (p.Val141Met) single nucleotide variant IGF2-related condition [RCV003409983]|not provided [RCV002943193] Chr11:2133109 [GRCh38]
Chr11:2154339 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.157+18G>C single nucleotide variant not provided [RCV002587650] Chr11:2135349 [GRCh38]
Chr11:2156579 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.157+15G>C single nucleotide variant not provided [RCV002585805] Chr11:2135352 [GRCh38]
Chr11:2156582 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.357G>A (p.Trp119Ter) single nucleotide variant Silver-Russell syndrome 3 [RCV003228775] Chr11:2133173 [GRCh38]
Chr11:2154403 [GRCh37]
Chr11:11p15.5
likely pathogenic
NM_000612.6(IGF2):c.243_244del (p.Glu81fs) microsatellite Silver-Russell syndrome 3 [RCV003223520] Chr11:2133579..2133580 [GRCh38]
Chr11:2154809..2154810 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.10C>G (p.Pro4Ala) single nucleotide variant Inborn genetic diseases [RCV003208516] Chr11:2135514 [GRCh38]
Chr11:2156744 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001042376.3(INS-IGF2):c.427G>A (p.Glu143Lys) single nucleotide variant Inborn genetic diseases [RCV003345216] Chr11:2147788 [GRCh38]
Chr11:2169018 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.157+5G>A single nucleotide variant IGF2-related condition [RCV003394389] Chr11:2135362 [GRCh38]
Chr11:2156592 [GRCh37]
Chr11:11p15.5
pathogenic
NM_000612.6(IGF2):c.412C>T (p.Arg138Trp) single nucleotide variant Inborn genetic diseases [RCV003370126] Chr11:2133118 [GRCh38]
Chr11:2154348 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.-6-2A>G single nucleotide variant Silver-Russell syndrome 3 [RCV003479529] Chr11:2135531 [GRCh38]
Chr11:2156761 [GRCh37]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:192764-3362853)x3 copy number gain not provided [RCV003484828] Chr11:192764..3362853 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.232G>A (p.Ala78Thr) single nucleotide variant not specified [RCV003479820] Chr11:2133591 [GRCh38]
Chr11:2154821 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001042376.3(INS-IGF2):c.378T>G (p.Ala126=) single nucleotide variant not provided [RCV003424765] Chr11:2149155 [GRCh38]
Chr11:2170385 [GRCh37]
Chr11:11p15.5
likely benign
GRCh37/hg19 11p15.5-15.4(chr11:230615-8821443)x3 copy number gain Russell-Silver syndrome [RCV003444025] Chr11:230615..8821443 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000612.6(IGF2):c.5G>A (p.Gly2Glu) single nucleotide variant not provided [RCV003849215] Chr11:2135519 [GRCh38]
Chr11:2156749 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.79C>T (p.Arg27Cys) single nucleotide variant not provided [RCV003696281] Chr11:2135445 [GRCh38]
Chr11:2156675 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.94C>T (p.Leu32=) single nucleotide variant not provided [RCV003829164] Chr11:2135430 [GRCh38]
Chr11:2156660 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.54C>T (p.Phe18=) single nucleotide variant not provided [RCV003779174] Chr11:2135470 [GRCh38]
Chr11:2156700 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.157+8G>C single nucleotide variant not provided [RCV003713113] Chr11:2135359 [GRCh38]
Chr11:2156589 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.517C>T (p.Pro173Ser) single nucleotide variant not provided [RCV003882429] Chr11:2133013 [GRCh38]
Chr11:2154243 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.217C>T (p.Arg73Cys) single nucleotide variant not provided [RCV003573305] Chr11:2133606 [GRCh38]
Chr11:2154836 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.305C>T (p.Pro102Leu) single nucleotide variant not provided [RCV003717061] Chr11:2133518 [GRCh38]
Chr11:2154748 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.318C>T (p.Pro106=) single nucleotide variant not provided [RCV003702596] Chr11:2133212 [GRCh38]
Chr11:2154442 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.307-11T>G single nucleotide variant not provided [RCV003700947] Chr11:2133234 [GRCh38]
Chr11:2154464 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.145G>A (p.Gly49Ser) single nucleotide variant not provided [RCV003671201] Chr11:2135379 [GRCh38]
Chr11:2156609 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.158-20C>A single nucleotide variant not provided [RCV003814468] Chr11:2133685 [GRCh38]
Chr11:2154915 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.438C>T (p.Leu146=) single nucleotide variant not provided [RCV003724892] Chr11:2133092 [GRCh38]
Chr11:2154322 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.460C>T (p.Arg154Cys) single nucleotide variant not provided [RCV003816268] Chr11:2133070 [GRCh38]
Chr11:2154300 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.198C>T (p.Ile66=) single nucleotide variant not provided [RCV003822229] Chr11:2133625 [GRCh38]
Chr11:2154855 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.418C>T (p.His140Tyr) single nucleotide variant not provided [RCV003682273] Chr11:2133112 [GRCh38]
Chr11:2154342 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.403C>T (p.Arg135Cys) single nucleotide variant not provided [RCV003709789] Chr11:2133127 [GRCh38]
Chr11:2154357 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.321A>C (p.Arg107Ser) single nucleotide variant not provided [RCV003867389] Chr11:2133209 [GRCh38]
Chr11:2154439 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.166G>A (p.Ala56Thr) single nucleotide variant not provided [RCV003722734] Chr11:2133657 [GRCh38]
Chr11:2154887 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.372G>A (p.Gln124=) single nucleotide variant not provided [RCV003711544] Chr11:2133158 [GRCh38]
Chr11:2154388 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.420C>T (p.His140=) single nucleotide variant not provided [RCV003821778] Chr11:2133110 [GRCh38]
Chr11:2154340 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.293C>T (p.Pro98Leu) single nucleotide variant not provided [RCV003730990] Chr11:2133530 [GRCh38]
Chr11:2154760 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_001127598.3(IGF2):c.39C>G (p.Pro13=) single nucleotide variant IGF2-related condition [RCV003974049] Chr11:2140258 [GRCh38]
Chr11:2161488 [GRCh37]
Chr11:11p15.5
benign
NM_000612.6(IGF2):c.14T>A (p.Met5Lys) single nucleotide variant IGF2-related condition [RCV003919492] Chr11:2135510 [GRCh38]
Chr11:2156740 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.513C>A (p.Ala171=) single nucleotide variant not specified [RCV003988233] Chr11:2133017 [GRCh38]
Chr11:2154247 [GRCh37]
Chr11:11p15.5
likely benign
NM_000612.6(IGF2):c.521A>C (p.Glu174Ala) single nucleotide variant IGF2-related condition [RCV003982701] Chr11:2133009 [GRCh38]
Chr11:2154239 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000612.6(IGF2):c.181C>T (p.Arg61Cys) single nucleotide variant IGF2-related condition [RCV003976354] Chr11:2133642 [GRCh38]
Chr11:2154872 [GRCh37]
Chr11:11p15.5
uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR125B1hsa-miR-125b-5pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//Western Functional MTI21200031
MIRLET7A2hsa-let-7a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI17974952
MIR125B2hsa-miR-125b-5pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//Western Functional MTI21200031
MIR615hsa-miR-615-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22819824
MIR615hsa-miR-615-5pOncomiRDBexternal_infoNANA22819824
MIRLET7A1hsa-let-7a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI17974952
MIR150hsa-miR-150-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI21200031

Predicted Target Of
Summary Value
Count of predictions:9376
Count of miRNA genes:938
Interacting mature miRNAs:1172
Transcripts:ENST00000300632, ENST00000381389, ENST00000381392, ENST00000381395, ENST00000381406, ENST00000416167, ENST00000418738, ENST00000434045
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
A002D21  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,384 - 2,150,510UniSTSGRCh37
Build 36112,106,960 - 2,107,086RGDNCBI36
Celera112,186,875 - 2,187,001RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,940,906 - 1,941,032UniSTS
GeneMap99-GB4 RH Map1122.72UniSTS
NCBI RH Map1110.0UniSTS
G44328  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,571 - 2,153,745UniSTSGRCh37
Build 36112,110,147 - 2,110,321RGDNCBI36
Celera112,190,077 - 2,190,251RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,104 - 1,944,278UniSTS
D11S4734  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,170,382 - 2,170,562UniSTSGRCh37
Build 36112,126,958 - 2,127,138RGDNCBI36
Celera112,206,887 - 2,207,067RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,960,644 - 1,960,824UniSTS
GDB:187027  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,461 - 2,153,696UniSTSGRCh37
Build 36112,110,037 - 2,110,272RGDNCBI36
Celera112,189,967 - 2,190,202RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,994 - 1,944,229UniSTS
GDB:438178  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,402 - 2,153,696UniSTSGRCh37
Build 36112,109,978 - 2,110,272RGDNCBI36
Celera112,189,908 - 2,190,202RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,935 - 1,944,229UniSTS
GDB:572840  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,405 - 2,153,696UniSTSGRCh37
Build 36112,109,981 - 2,110,272RGDNCBI36
Celera112,189,911 - 2,190,202RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,938 - 1,944,229UniSTS
IGF2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,169,615 - 2,170,122UniSTSGRCh37
GRCh37112,152,567 - 2,153,356UniSTSGRCh37
Build 36112,126,191 - 2,126,698RGDNCBI36
Celera112,189,058 - 2,189,862UniSTS
Celera112,206,120 - 2,206,627RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,959,877 - 1,960,384UniSTS
HuRef111,943,089 - 1,943,889UniSTS
GeneMap99-GB4 RH Map1116.42UniSTS
NCBI RH Map1110.0UniSTS
STS-H87011  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,578 - 2,151,797UniSTSGRCh37
Build 36112,108,154 - 2,108,373RGDNCBI36
Celera112,188,069 - 2,188,288RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,100 - 1,942,319UniSTS
GeneMap99-GB4 RH Map1118.93UniSTS
NCBI RH Map1110.0UniSTS
PMC124986P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,152,579 - 2,153,378UniSTSGRCh37
Build 36112,109,155 - 2,109,954RGDNCBI36
Celera112,189,070 - 2,189,884RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,101 - 1,943,911UniSTS
PMC151856P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,154,415 - 2,154,823UniSTSGRCh37
Build 36112,110,991 - 2,111,399RGDNCBI36
Celera112,190,921 - 2,191,329RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,948 - 1,945,356UniSTS
PMC151856P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,961 - 2,154,293UniSTSGRCh37
Build 36112,110,537 - 2,110,869RGDNCBI36
Celera112,190,467 - 2,190,799RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,494 - 1,944,826UniSTS
PMC21842P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,466 - 2,153,696UniSTSGRCh37
Build 36112,110,042 - 2,110,272RGDNCBI36
Celera112,189,972 - 2,190,202RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,999 - 1,944,229UniSTS
ECD00261  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,157,224 - 2,158,142UniSTSGRCh37
Build 36112,113,800 - 2,114,718RGDNCBI36
Celera112,193,731 - 2,194,649RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,947,745 - 1,948,663UniSTS
ECD00298  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,156,257 - 2,157,173UniSTSGRCh37
Build 36112,112,833 - 2,113,749RGDNCBI36
Celera112,192,763 - 2,193,680RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,946,778 - 1,947,694UniSTS
ECD00602  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,155,340 - 2,156,238UniSTSGRCh37
Build 36112,111,916 - 2,112,814RGDNCBI36
Celera112,191,846 - 2,192,744RGD
Cytogenetic Map11p15.5UniSTS
ECD00988  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,402 - 2,154,284UniSTSGRCh37
Build 36112,109,978 - 2,110,860RGDNCBI36
Celera112,189,908 - 2,190,790RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,935 - 1,944,817UniSTS
ECD02194  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,169,406 - 2,170,244UniSTSGRCh37
Build 36112,125,982 - 2,126,820RGDNCBI36
Celera112,205,911 - 2,206,749RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,959,668 - 1,960,506UniSTS
ECD02732  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,171,990 - 2,172,809UniSTSGRCh37
Build 36112,128,566 - 2,129,385RGDNCBI36
Celera112,208,497 - 2,209,316RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,962,252 - 1,963,071UniSTS
ECD02763  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,166,711 - 2,167,529UniSTSGRCh37
Build 36112,123,287 - 2,124,105RGDNCBI36
Celera112,203,216 - 2,204,034RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,956,973 - 1,957,791UniSTS
ECD02927  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,170,293 - 2,171,105UniSTSGRCh37
Build 36112,126,869 - 2,127,681RGDNCBI36
Celera112,206,798 - 2,207,612RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,960,555 - 1,961,367UniSTS
ECD02954  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,163,166 - 2,163,977UniSTSGRCh37
Build 36112,119,742 - 2,120,553RGDNCBI36
Celera112,199,673 - 2,200,484RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,953,430 - 1,954,241UniSTS
ECD03070  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,164,000 - 2,164,807UniSTSGRCh37
Build 36112,120,576 - 2,121,383RGDNCBI36
Celera112,200,507 - 2,201,314RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,954,264 - 1,955,071UniSTS
ECD03071  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,165,812 - 2,166,619UniSTSGRCh37
Build 36112,122,388 - 2,123,195RGDNCBI36
Celera112,202,317 - 2,203,124RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,956,074 - 1,956,881UniSTS
ECD03096  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,171,126 - 2,171,932UniSTSGRCh37
Build 36112,127,702 - 2,128,508RGDNCBI36
Celera112,207,633 - 2,208,439RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,961,388 - 1,962,194UniSTS
ECD03179  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,164,942 - 2,165,745UniSTSGRCh37
Build 36112,121,518 - 2,122,321RGDNCBI36
Celera112,201,449 - 2,202,250RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,955,206 - 1,956,007UniSTS
ECD03988  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,154,433 - 2,155,211UniSTSGRCh37
Build 36112,111,009 - 2,111,787RGDNCBI36
Celera112,190,939 - 2,191,717RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,966 - 1,945,744UniSTS
ECD04781  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,167,680 - 2,168,434UniSTSGRCh37
Build 36112,124,256 - 2,125,010RGDNCBI36
Celera112,204,185 - 2,204,939RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,957,942 - 1,958,696UniSTS
ECD05174  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,047 - 2,151,790UniSTSGRCh37
Build 36112,107,623 - 2,108,366RGDNCBI36
Celera112,187,538 - 2,188,281RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,941,569 - 1,942,312UniSTS
ECD05737  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,923 - 2,152,651UniSTSGRCh37
Build 36112,108,499 - 2,109,227RGDNCBI36
Celera112,188,414 - 2,189,142RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,445 - 1,943,173UniSTS
ECD06903  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,160,901 - 2,161,597UniSTSGRCh37
Build 36112,117,477 - 2,118,173RGDNCBI36
Celera112,197,408 - 2,198,104RGD
Cytogenetic Map11p15.5UniSTS
ECD07090  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,168,620 - 2,169,311UniSTSGRCh37
Build 36112,125,196 - 2,125,887RGDNCBI36
Celera112,205,125 - 2,205,816RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,958,882 - 1,959,573UniSTS
ECD07233  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,158,524 - 2,159,211UniSTSGRCh37
Build 36112,115,100 - 2,115,787RGDNCBI36
Celera112,195,031 - 2,195,718RGD
Cytogenetic Map11p15.5UniSTS
ECD07757  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,162,353 - 2,163,026UniSTSGRCh37
Build 36112,118,929 - 2,119,602RGDNCBI36
Celera112,198,860 - 2,199,533RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,952,617 - 1,953,290UniSTS
ECD08420  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,215 - 2,150,870UniSTSGRCh37
Build 36112,106,791 - 2,107,446RGDNCBI36
Celera112,186,706 - 2,187,361RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,940,737 - 1,941,392UniSTS
ECD11676  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,161,623 - 2,162,188UniSTSGRCh37
Build 36112,118,199 - 2,118,764RGDNCBI36
Celera112,198,130 - 2,198,695RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,951,887 - 1,952,452UniSTS
ECD21742  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,159,497 - 2,159,738UniSTSGRCh37
Build 36112,116,073 - 2,116,314RGDNCBI36
Celera112,196,004 - 2,196,245RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,949,721 - 1,949,962UniSTS
STS-S77035  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,154,008 - 2,154,221UniSTSGRCh37
Build 36112,110,584 - 2,110,797RGDNCBI36
Celera112,190,514 - 2,190,727RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,541 - 1,944,754UniSTS
GeneMap99-GB4 RH Map735.78UniSTS
NCBI RH Map71.7UniSTS
REN116981  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,439 - 2,150,664UniSTSGRCh37
Build 36112,107,015 - 2,107,240RGDNCBI36
Celera112,186,930 - 2,187,155RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,940,961 - 1,941,186UniSTS
REN116982  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,652 - 2,150,880UniSTSGRCh37
Build 36112,107,228 - 2,107,456RGDNCBI36
Celera112,187,143 - 2,187,371RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,941,174 - 1,941,402UniSTS
REN116983  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,859 - 2,151,118UniSTSGRCh37
Build 36112,107,435 - 2,107,694RGDNCBI36
Celera112,187,350 - 2,187,609RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,941,381 - 1,941,640UniSTS
REN116984  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,106 - 2,151,337UniSTSGRCh37
Build 36112,107,682 - 2,107,913RGDNCBI36
Celera112,187,597 - 2,187,828RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,941,628 - 1,941,859UniSTS
REN116985  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,323 - 2,151,581UniSTSGRCh37
Build 36112,107,899 - 2,108,157RGDNCBI36
Celera112,187,814 - 2,188,072RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,941,845 - 1,942,103UniSTS
REN116986  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,558 - 2,151,811UniSTSGRCh37
Build 36112,108,134 - 2,108,387RGDNCBI36
Celera112,188,049 - 2,188,302RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,080 - 1,942,333UniSTS
REN116987  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,904 - 2,152,131UniSTSGRCh37
Build 36112,108,480 - 2,108,707RGDNCBI36
Celera112,188,395 - 2,188,622RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,426 - 1,942,653UniSTS
REN116988  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,152,151 - 2,152,381UniSTSGRCh37
Build 36112,108,727 - 2,108,957RGDNCBI36
Celera112,188,642 - 2,188,872RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,673 - 1,942,903UniSTS
REN116989  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,152,378 - 2,152,603UniSTSGRCh37
Build 36112,108,954 - 2,109,179RGDNCBI36
Celera112,188,869 - 2,189,094RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,900 - 1,943,125UniSTS
REN116990  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,152,579 - 2,152,806UniSTSGRCh37
GRCh37112,152,579 - 2,152,729UniSTSGRCh37
Build 36112,109,155 - 2,109,305RGDNCBI36
Celera112,189,070 - 2,189,220RGD
Celera112,189,070 - 2,189,497UniSTS
Celera112,189,070 - 2,189,297UniSTS
Cytogenetic Map11p15.5UniSTS
HuRef111,943,101 - 1,943,251UniSTS
HuRef111,943,101 - 1,943,328UniSTS
HuRef111,943,102 - 1,943,529UniSTS
REN116991  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,227 - 2,153,457UniSTSGRCh37
Build 36112,109,803 - 2,110,033RGDNCBI36
Celera112,189,714 - 2,189,963RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,943,741 - 1,943,990UniSTS
REN116992  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,470 - 2,153,707UniSTSGRCh37
Build 36112,110,046 - 2,110,283RGDNCBI36
Celera112,189,976 - 2,190,213RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,003 - 1,944,240UniSTS
REN116993  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,683 - 2,153,954UniSTSGRCh37
Build 36112,110,259 - 2,110,530RGDNCBI36
Celera112,190,189 - 2,190,460RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,216 - 1,944,487UniSTS
REN116994  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,153,933 - 2,154,157UniSTSGRCh37
Build 36112,110,509 - 2,110,733RGDNCBI36
Celera112,190,439 - 2,190,663RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,466 - 1,944,690UniSTS
REN116995  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,154,149 - 2,154,412UniSTSGRCh37
Build 36112,110,725 - 2,110,988RGDNCBI36
Celera112,190,655 - 2,190,918RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,944,682 - 1,944,945UniSTS
REN117016  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,159,629 - 2,159,877UniSTSGRCh37
Build 36112,116,205 - 2,116,453RGDNCBI36
Celera112,196,136 - 2,196,384RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,949,853 - 1,950,101UniSTS
REN117019  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,162,169 - 2,162,409UniSTSGRCh37
Build 36112,118,745 - 2,118,985RGDNCBI36
Celera112,198,676 - 2,198,916RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,952,433 - 1,952,673UniSTS
REN117053  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,170,540 - 2,170,770UniSTSGRCh37
Build 36112,127,116 - 2,127,346RGDNCBI36
Celera112,207,045 - 2,207,275RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,960,802 - 1,961,032UniSTS
SGC35182  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,151,657 - 2,151,806UniSTSGRCh37
Build 36112,108,233 - 2,108,382RGDNCBI36
Celera112,188,148 - 2,188,297RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,942,179 - 1,942,328UniSTS
GeneMap99-GB4 RH Map1117.53UniSTS
Whitehead-RH Map1126.8UniSTS
NCBI RH Map1110.0UniSTS
WI-14149  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37112,150,361 - 2,150,464UniSTSGRCh37
Build 36112,106,937 - 2,107,040RGDNCBI36
Celera112,186,852 - 2,186,955RGD
Cytogenetic Map11p15.5UniSTS
HuRef111,940,883 - 1,940,986UniSTS
GeneMap99-GB4 RH Map118.95UniSTS
Whitehead-RH Map1130.7UniSTS
D8S2278  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map4q32.1UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map3p25.3-p24.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map2q11.2-q12.1UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map10q11UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map12q21.31UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map7q34-q35UniSTS
Cytogenetic MapXp22.1UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map2q37UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map4q34.1UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map6q25UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map6p22UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map2p23.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map12p12.3UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map15q22.1UniSTS
Cytogenetic Map1p34-p33UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map3q25.31UniSTS
Cytogenetic Map14q22UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map3q26.32UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map13q11UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map14q12-q13UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map17q11.2-q12UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map4q31UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map15q15-q21.1UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map4q22.1-q23UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map17q22-q23.2UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map18q22.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic MapXq26.1UniSTS
Cytogenetic Map4q21.21UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.32UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map3q13.13UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map10p11.23UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map13q33.1UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map1q31-q41UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map14q23UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map9p21UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map3p12.1UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map12q14.3-q15UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map3q28UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map2q23.3UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map8p12-p11UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map3p21.32UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map13q32.3UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map3p26.1UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map19q13.13UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map9q33.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map4q32.3UniSTS
Cytogenetic Map3p14.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map21q21.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map8q23.3UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map10q21-q22UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map17q24UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map7p13-p11.1UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map7q31.3UniSTS
Cytogenetic MapXp22.13UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1p13-p12UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map10q21.1UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map14q31UniSTS
GDB:677440  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11p15.5UniSTS
IGF2  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11p15.5UniSTS
GeneMap99-GB4 RH Map1116.52UniSTS
NCBI RH Map1110.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High 17 34 32 32 2 4 6 10 35 8 1 1
Medium 1575 1938 1346 427 190 355 2930 1893 1003 149 1036 840 78 1198 2139 3
Low 771 601 319 151 679 61 1369 275 2612 206 336 652 94 1 6 647 1
Below cutoff 48 442 19 10 490 14 42 18 81 47 38 80 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_008849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NG_050578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001007139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA040827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF318382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF517226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK074614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK126688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY971350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE270173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM667567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP233290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ014465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT007013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN277570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA641853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU326141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU622024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB571441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GM741469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM481219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM481220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S51971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S77035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X03562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y13633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000381389   ⟹   ENSP00000370796
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,132,673 - 2,141,016 (-)Ensembl
RefSeq Acc Id: ENST00000381392   ⟹   ENSP00000370799
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,132,640 - 2,137,287 (-)Ensembl
RefSeq Acc Id: ENST00000381395   ⟹   ENSP00000370802
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,129,112 - 2,137,290 (-)Ensembl
RefSeq Acc Id: ENST00000381406   ⟹   ENSP00000370813
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,129,112 - 2,138,974 (-)Ensembl
RefSeq Acc Id: ENST00000416167   ⟹   ENSP00000414497
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,129,117 - 2,139,389 (-)Ensembl
RefSeq Acc Id: ENST00000418738   ⟹   ENSP00000402047
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,132,716 - 2,137,305 (-)Ensembl
RefSeq Acc Id: ENST00000434045   ⟹   ENSP00000391826
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,132,500 - 2,141,238 (-)Ensembl
RefSeq Acc Id: ENST00000476874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,148,934 - 2,158,336 (-)Ensembl
RefSeq Acc Id: ENST00000481781   ⟹   ENSP00000511998
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,132,500 - 2,158,391 (-)Ensembl
RefSeq Acc Id: ENST00000695541   ⟹   ENSP00000511997
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl112,131,395 - 2,149,579 (-)Ensembl
RefSeq Acc Id: NM_000612   ⟹   NP_000603
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,117 - 2,139,389 (-)NCBI
GRCh37112,150,346 - 2,179,611 (-)NCBI
Build 36112,106,923 - 2,116,780 (-)NCBI Archive
HuRef111,940,869 - 1,961,095 (-)ENTREZGENE
CHM1_1112,148,968 - 2,158,828 (-)NCBI
T2T-CHM13v2.0112,216,758 - 2,227,040 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001007139   ⟹   NP_001007140
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,117 - 2,149,566 (-)NCBI
GRCh37112,150,346 - 2,179,611 (-)NCBI
Build 36112,106,923 - 2,127,409 (-)NCBI Archive
HuRef111,940,869 - 1,961,095 (-)ENTREZGENE
CHM1_1112,148,968 - 2,169,786 (-)NCBI
T2T-CHM13v2.0112,216,758 - 2,237,216 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001127598   ⟹   NP_001121070
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,117 - 2,140,943 (-)NCBI
GRCh37112,150,346 - 2,179,611 (-)NCBI
HuRef111,940,869 - 1,961,095 (-)ENTREZGENE
CHM1_1112,148,968 - 2,161,307 (-)NCBI
T2T-CHM13v2.0112,216,758 - 2,228,596 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291861   ⟹   NP_001278790
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,117 - 2,137,288 (-)NCBI
CHM1_1112,148,968 - 2,157,142 (-)NCBI
T2T-CHM13v2.0112,216,758 - 2,224,941 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291862   ⟹   NP_001278791
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,117 - 2,140,943 (-)NCBI
CHM1_1112,148,968 - 2,161,307 (-)NCBI
T2T-CHM13v2.0112,216,758 - 2,228,596 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000603 (Get FASTA)   NCBI Sequence Viewer  
  NP_001007140 (Get FASTA)   NCBI Sequence Viewer  
  NP_001121070 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278790 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278791 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA52443 (Get FASTA)   NCBI Sequence Viewer  
  AAA52536 (Get FASTA)   NCBI Sequence Viewer  
  AAA52544 (Get FASTA)   NCBI Sequence Viewer  
  AAA52545 (Get FASTA)   NCBI Sequence Viewer  
  AAA60088 (Get FASTA)   NCBI Sequence Viewer  
  AAB34155 (Get FASTA)   NCBI Sequence Viewer  
  AAD14908 (Get FASTA)   NCBI Sequence Viewer  
  AAH00531 (Get FASTA)   NCBI Sequence Viewer  
  AAL55889 (Get FASTA)   NCBI Sequence Viewer  
  AAM51825 (Get FASTA)   NCBI Sequence Viewer  
  AAP35659 (Get FASTA)   NCBI Sequence Viewer  
  AAY40360 (Get FASTA)   NCBI Sequence Viewer  
  ABD93451 (Get FASTA)   NCBI Sequence Viewer  
  ACC95538 (Get FASTA)   NCBI Sequence Viewer  
  ADO21454 (Get FASTA)   NCBI Sequence Viewer  
  ADO21455 (Get FASTA)   NCBI Sequence Viewer  
  BAG36657 (Get FASTA)   NCBI Sequence Viewer  
  BAG54360 (Get FASTA)   NCBI Sequence Viewer  
  CAA25426 (Get FASTA)   NCBI Sequence Viewer  
  CAA27155 (Get FASTA)   NCBI Sequence Viewer  
  CAA27156 (Get FASTA)   NCBI Sequence Viewer  
  CAA27157 (Get FASTA)   NCBI Sequence Viewer  
  CAA27249 (Get FASTA)   NCBI Sequence Viewer  
  CAA29516 (Get FASTA)   NCBI Sequence Viewer  
  CAA29517 (Get FASTA)   NCBI Sequence Viewer  
  CAA29518 (Get FASTA)   NCBI Sequence Viewer  
  CAA30717 (Get FASTA)   NCBI Sequence Viewer  
  CAR95138 (Get FASTA)   NCBI Sequence Viewer  
  CAV31678 (Get FASTA)   NCBI Sequence Viewer  
  EAX02485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000370796
  ENSP00000370796.1
  ENSP00000370799.1
  ENSP00000370802.1
  ENSP00000370813.4
  ENSP00000391826
  ENSP00000391826.2
  ENSP00000402047
  ENSP00000402047.2
  ENSP00000414497
  ENSP00000414497.2
  ENSP00000511997
  ENSP00000511997.1
  ENSP00000511998.1
GenBank Protein P01344 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007140   ⟸   NM_001007139
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q9UC68 (UniProtKB/Swiss-Prot),   Q1WM26 (UniProtKB/Swiss-Prot),   Q14299 (UniProtKB/Swiss-Prot),   P78449 (UniProtKB/Swiss-Prot),   E3UN45 (UniProtKB/Swiss-Prot),   C9JAF2 (UniProtKB/Swiss-Prot),   B7WP08 (UniProtKB/Swiss-Prot),   B3KX48 (UniProtKB/Swiss-Prot),   Q9UC69 (UniProtKB/Swiss-Prot),   P01344 (UniProtKB/Swiss-Prot),   A8K6C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001121070   ⟸   NM_001127598
- Peptide Label: isoform 2
- UniProtKB: P01344 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_000603   ⟸   NM_000612
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q9UC68 (UniProtKB/Swiss-Prot),   Q1WM26 (UniProtKB/Swiss-Prot),   Q14299 (UniProtKB/Swiss-Prot),   P78449 (UniProtKB/Swiss-Prot),   E3UN45 (UniProtKB/Swiss-Prot),   C9JAF2 (UniProtKB/Swiss-Prot),   B7WP08 (UniProtKB/Swiss-Prot),   B3KX48 (UniProtKB/Swiss-Prot),   Q9UC69 (UniProtKB/Swiss-Prot),   P01344 (UniProtKB/Swiss-Prot),   A8K6C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278791   ⟸   NM_001291862
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q9UC68 (UniProtKB/Swiss-Prot),   Q1WM26 (UniProtKB/Swiss-Prot),   Q14299 (UniProtKB/Swiss-Prot),   P78449 (UniProtKB/Swiss-Prot),   E3UN45 (UniProtKB/Swiss-Prot),   C9JAF2 (UniProtKB/Swiss-Prot),   B7WP08 (UniProtKB/Swiss-Prot),   B3KX48 (UniProtKB/Swiss-Prot),   Q9UC69 (UniProtKB/Swiss-Prot),   P01344 (UniProtKB/Swiss-Prot),   A8K6C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278790   ⟸   NM_001291861
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q9UC68 (UniProtKB/Swiss-Prot),   Q1WM26 (UniProtKB/Swiss-Prot),   Q14299 (UniProtKB/Swiss-Prot),   P78449 (UniProtKB/Swiss-Prot),   E3UN45 (UniProtKB/Swiss-Prot),   C9JAF2 (UniProtKB/Swiss-Prot),   B7WP08 (UniProtKB/Swiss-Prot),   B3KX48 (UniProtKB/Swiss-Prot),   Q9UC69 (UniProtKB/Swiss-Prot),   P01344 (UniProtKB/Swiss-Prot),   A8K6C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000414497   ⟸   ENST00000416167
RefSeq Acc Id: ENSP00000402047   ⟸   ENST00000418738
RefSeq Acc Id: ENSP00000391826   ⟸   ENST00000434045
RefSeq Acc Id: ENSP00000370796   ⟸   ENST00000381389
RefSeq Acc Id: ENSP00000370802   ⟸   ENST00000381395
RefSeq Acc Id: ENSP00000370799   ⟸   ENST00000381392
RefSeq Acc Id: ENSP00000370813   ⟸   ENST00000381406
RefSeq Acc Id: ENSP00000511997   ⟸   ENST00000695541
RefSeq Acc Id: ENSP00000511998   ⟸   ENST00000481781
Protein Domains
Insulin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01344-F1-model_v2 AlphaFold P01344 1-180 view protein structure

Promoters
RGD ID:6850060
Promoter ID:EP28009
Type:single initiation site
Name:HS_IGF2_4
Description:Insulin-like growth factor II, IGF2 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 155; Mammalian insulin-like growth factor 2 E3/E4.
Alternative Promoters:alternative promoter #4 of 4; 5' exon 4; site 1.; see alsoEP17071  EP28010  EP17072  
Tissues & Cell Lines:fetus, adult, nonhepatic tissue
Experiment Methods:Nuclease protection; experiments performed with closely related; gene; Primer extension; experiments performed with closely related; gene
Position:
Human AssemblyChrPosition (strand)Source
Build 36112,115,093 - 2,115,153EPD
RGD ID:6850056
Promoter ID:EP17072
Type:single initiation site
Name:HS_IGF2_3
Description:Insulin-like growth factor II, IGF2 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 137; Mammalian insulin-like growth factor 2 E2/E3.
Alternative Promoters:alternative promoter #3 of 4; 5' exon 3; site 1.; see alsoEP17071  EP28010  EP28009  
Tissues & Cell Lines:fetus, adult, nonhepatic tissue
Experiment Methods:Sequencing of a full-length cDNA
Position:
Human AssemblyChrPosition (strand)Source
Build 36112,117,199 - 2,117,259EPD
RGD ID:6850052
Promoter ID:EP28010
Type:initiation region
Name:HS_IGF2_2
Description:Insulin-like growth factor II, IGF2 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:alternative promoter #2 of 4; 5' exon 2; site 1.; see alsoEP17071  EP17072  EP28009  
Tissues & Cell Lines:fetus, liver
Experiment Methods:Primer extension
Position:
Human AssemblyChrPosition (strand)Source
Build 36112,119,052 - 2,119,112EPD
RGD ID:7219305
Promoter ID:EPDNEW_H15398
Type:initiation region
Name:IGF2_10
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,129,576 - 2,129,636EPDNEW
RGD ID:7219307
Promoter ID:EPDNEW_H15399
Type:initiation region
Name:IGF2_3
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,130,576 - 2,130,636EPDNEW
RGD ID:7219309
Promoter ID:EPDNEW_H15400
Type:initiation region
Name:IGF2_8
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,130,770 - 2,130,830EPDNEW
RGD ID:7219311
Promoter ID:EPDNEW_H15401
Type:initiation region
Name:IGF2_5
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,132,381 - 2,132,441EPDNEW
RGD ID:7219313
Promoter ID:EPDNEW_H15402
Type:initiation region
Name:IGF2_7
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,132,871 - 2,132,931EPDNEW
RGD ID:7219317
Promoter ID:EPDNEW_H15403
Type:initiation region
Name:IGF2_6
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,133,647 - 2,133,707EPDNEW
RGD ID:6850048
Promoter ID:EP17071
Type:single initiation site
Name:HS_IGF2_1
Description:Insulin-like growth factor II, IGF2 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:alternative promoter #1 of 4; 5' exon 1; site 1.; see alsoEP28010  EP17072  EP28009  
Tissues & Cell Lines:adult, liver
Experiment Methods:Primer extension
Position:
Human AssemblyChrPosition (strand)Source
Build 36112,136,189 - 2,136,249EPD
RGD ID:7219315
Promoter ID:EPDNEW_H15404
Type:multiple initiation site
Name:IGF2_2
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,137,288 - 2,137,348EPDNEW
RGD ID:7219321
Promoter ID:EPDNEW_H15405
Type:initiation region
Name:IGF2_4
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,138,352 - 2,138,412EPDNEW
RGD ID:7219319
Promoter ID:EPDNEW_H15406
Type:initiation region
Name:IGF2_9
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15405  EPDNEW_H15408  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,138,642 - 2,138,702EPDNEW
RGD ID:7219325
Promoter ID:EPDNEW_H15407
Type:initiation region
Name:IGF2_1
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15408  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,139,389 - 2,139,449EPDNEW
RGD ID:7219323
Promoter ID:EPDNEW_H15408
Type:initiation region
Name:IGF2_11
Description:insulin like growth factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15398  EPDNEW_H15399  EPDNEW_H15400  EPDNEW_H15401  EPDNEW_H15402  EPDNEW_H15404  EPDNEW_H15403  EPDNEW_H15406  EPDNEW_H15405  EPDNEW_H15407  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38112,141,246 - 2,141,306EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5466 AgrOrtholog
COSMIC IGF2 COSMIC
Ensembl Genes ENSG00000167244 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000381389 ENTREZGENE
  ENST00000381389.5 UniProtKB/Swiss-Prot
  ENST00000381392.5 UniProtKB/Swiss-Prot
  ENST00000381395.5 UniProtKB/Swiss-Prot
  ENST00000381406.8 UniProtKB/Swiss-Prot
  ENST00000416167 ENTREZGENE
  ENST00000416167.7 UniProtKB/Swiss-Prot
  ENST00000418738 ENTREZGENE
  ENST00000418738.2 UniProtKB/Swiss-Prot
  ENST00000434045 ENTREZGENE
  ENST00000434045.6 UniProtKB/Swiss-Prot
  ENST00000481781.3 UniProtKB/Swiss-Prot
  ENST00000695541 ENTREZGENE
  ENST00000695541.1 UniProtKB/Swiss-Prot
Gene3D-CATH Insulin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000167244 GTEx
HGNC ID HGNC:5466 ENTREZGENE
Human Proteome Map IGF2 Human Proteome Map
InterPro IGF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGF2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin-like_growth_factor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin_family UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3481 UniProtKB/Swiss-Prot
NCBI Gene 3481 ENTREZGENE
OMIM 147470 OMIM
PANTHER INSULIN-LIKE GROWTH FACTOR II UniProtKB/Swiss-Prot
  INSULIN-LIKE GROWTH FACTOR II UniProtKB/Swiss-Prot
  INSULIN-LIKE GROWTH FACTOR II UniProtKB/TrEMBL
  INSULIN-LIKE GROWTH FACTOR II UniProtKB/TrEMBL
Pfam IGF2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Insulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29699 PharmGKB
PRINTS INSLNLIKEGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INSLNLIKEGF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INSULINFAMLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INSULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
SMART IlGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56994 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K6C9 ENTREZGENE, UniProtKB/TrEMBL
  B2MUX6_HUMAN UniProtKB/TrEMBL
  B3KX48 ENTREZGENE
  B7WP08 ENTREZGENE
  C9JAF2 ENTREZGENE
  E3UN45 ENTREZGENE
  E3UN46_HUMAN UniProtKB/TrEMBL
  IGF2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  P78449 ENTREZGENE
  Q14299 ENTREZGENE
  Q1WM26 ENTREZGENE
  Q9UC68 ENTREZGENE
  Q9UC69 ENTREZGENE
UniProt Secondary B3KX48 UniProtKB/Swiss-Prot
  B7WP08 UniProtKB/Swiss-Prot
  C9JAF2 UniProtKB/Swiss-Prot
  E3UN45 UniProtKB/Swiss-Prot
  P78449 UniProtKB/Swiss-Prot
  Q14299 UniProtKB/Swiss-Prot
  Q1WM26 UniProtKB/Swiss-Prot
  Q9UC68 UniProtKB/Swiss-Prot
  Q9UC69 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 IGF2  insulin like growth factor 2    insulin-like growth factor 2  Symbol and/or name change 5135510 APPROVED
2014-09-24 IGF2  insulin-like growth factor 2    insulin-like growth factor 2 (somatomedin A)  Symbol and/or name change 5135510 APPROVED